Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

ABO Blood Groups and Risk of Cancer: a Systematic Review and Meta-analysis

  • Zhang, Bai-Lin (Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education) ;
  • He, Na (Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education) ;
  • Huang, Yu-Bei (Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education) ;
  • Song, Feng-Ju (Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education) ;
  • Chen, Ke-Xin (Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education)
  • Published : 2014.06.15
Download PDF
⟨ Previous Next ⟩

Abstract

Background: For decades, studies have been performed to evaluate the association between ABO blood groups and risk of cancer. However, whether ABO blood groups are associated with overall cancer risk remains unclear. We therefore conducted a meta-analysis of observational studies to assess this association. Materials and Methods: A search of Pubmed, Embase, ScienceDirect, Wiley, and Web of Knowledge databases (to May 2013) was supplemented by manual searches of bibliographies of key retrieved articles and relevant reviews. We included case-control studies and cohort studies with more than 100 cancer cases. Results: The search yielded 89 eligible studies that reported 100,554 cases at 30 cancer sites. For overall cancer risk, the pooled OR was 1.12 (95%CI: 1.09-1.16) for A vs. non- A groups, and 0.84 (95%CI: 0.80-0.88) for O vs. non-O groups. For individual cancer sites, blood group A was found to confer increased risk of gastric cancer (OR=1.18; 95%CI: 1.13-1.24), pancreatic cancer (OR=1.23; 95%CI: 1.15-1.32), breast cancer (OR=1.12; 95%CI: 1.01-1.24), ovarian cancer (OR=1.16; 95%CI: 1.04-1.27), and nasopharyngeal cancer (OR=1.17; 95%CI: 1.00-1.33). Blood group O was found to be linked to decreased risk of gastric cancer (OR=0.84; 95%CI: 0.80-0.88), pancreatic cancer (OR=0.75; 95%CI: 0.70-0.80), breast cancer (OR=0.90; 95%CI: 0.85-0.95), colorectal cancer (OR=0.89; 95%CI: 0.81-0.96), ovarian cancer (OR=0.76; 95%CI: 0.53-1.00), esophagus cancer (OR=0.94; 95%CI: 0.89-1.00), and nasopharyngeal cancer (OR=0.81; 95%CI: 0.70-0.91). Conclusions: Blood group A is associated with increased risk of cancer, and blood group O is associated with decreased risk of cancer.

Keywords

References

  1. Adelusi B (1977). Haemoglobin genotype, ABO blood groups and carcinoma of the cervix. J Trop Med Hyg, 80, 152-4.
  2. Aird I, Bentall HH, Mehigan JA, Roberts, JA (1954). The blood groups in relation to peptic ulceration and carcinoma of colon, rectum, breast, and bronchus; an association between the ABO groups and peptic ulceration. BMJ, 2, 315-21. https://doi.org/10.1136/bmj.2.4883.315
  3. Aird I, Bentall HH, Roberts JAF (1953). A relationship between cancer of stomach and the ABO blood groups. BMJ, 1, 799-801. https://doi.org/10.1136/bmj.1.4814.799
  4. Aird I, Lee DR, Roberts JA (1960). ABO blood groups and cancer of oesophagus, cancerof pancreas, and pituitary adenoma. Br Med J, 1, 1163-6. https://doi.org/10.1136/bmj.1.5180.1163
  5. Akhtar K (2011). Relationship between various cancers and ANOblood groups. Pathology, 13, 1.
  6. Akumabor PN, Okafor LA (1986). The ABO blood groups in relation to carcinoma of the stomach and duodenal ulcer in a Nigerian community. Public Health, 100, 116-8. https://doi.org/10.1016/S0033-3506(86)80008-7
  7. Ali A, Rasoul M, Abbas A, et al (2010). Relationship Between Esophageal Cancer and Blood Groups. World Appl Sci J, 8, 503-8.
  8. Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, et al (2009). Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet, 41, 986-90. https://doi.org/10.1038/ng.429
  9. Anderson DE, Haas C, et al (1984). Blood type A and familial breast cancer. Cancer, 54, 1845-9. https://doi.org/10.1002/1097-0142(19841101)54:9<1845::AID-CNCR2820540913>3.0.CO;2-5
  10. Annese V, Minervini M, Gabbrielli A, Gambassi G, Manna R (1990). ABO blood groups and cancer of the pancreas. Int J Pancreatol, 6, 81-8.
  11. Barbalic M, Dupuis J, Dehghan A, et al (2010). Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet, 19, 1863-72. https://doi.org/10.1093/hmg/ddq061
  12. Beasley WH (1960). Blood groups of gastric ulcer and carcinoma. BMJ, 1, 1167-72. https://doi.org/10.1136/bmj.1.5180.1167
  13. Beasley WH (1964). The abo blood groups of carcinoma of the oesophagus and of benign prostatic hyperplasia. J Clin Pathol, 17, 42-4. https://doi.org/10.1136/jcp.17.1.42
  14. Beckman L, Edlund AE (1961). ABO blood groups and gastric carcinoma. Data from Swedish hospital records. Acta Genet Stat Med, 11, 363-9.
  15. Begg CB, Mazumdar M (1994). Operating characteristics of a rank correlation test for publication bias. Biometrics, 50, 1088-101. https://doi.org/10.2307/2533446
  16. Ben Q, Wang K, Yuan Y, Li Z (2011). Pancreatic cancer incidence and outcome in relation to ABO blood groups among Han Chinese patients: a case-control study. Int J Cancer, 128, 1179-86. https://doi.org/10.1002/ijc.25426
  17. Billington BP (1956). Gastric cancer; relationships between ABO blood-groups, site, and epidemiology. Lancet, 271, 859-62.
  18. Birnbaum d, Menczel J (1959). ABO blood group distribution in ulcerative and malignant diseases of the gastrointestinal tract; incidence in three communal groups in Israel. Gastroenterology, 37, 210-3.
  19. Bjorkholm E (1984). Blood group distribution in women with ovarian cancer. Int J Epidemiol, 13, 15-7. https://doi.org/10.1093/ije/13.1.15
  20. Buckwalter JA, Knowler LA (1958). Blood donor controls for blood group disease researches. Am J Hum Genet, 10, 164-74.
  21. Costantini M, Fassio T, Canobbio L, et al (1990). Role of blood groups as prognostic factors in primary breast cancer. Oncol Basel, 47, 308-12. https://doi.org/10.1159/000226839
  22. Cotter CA, Staveley JM, Thompson HR (1961). ABO and Rh (D) blood groups and cancer of the stomach in Auckland. NZ Med J, 60, 372-4.
  23. de Giorgi V, Grazzini M, Gori A, et al (2011). ABO blood group and risk of cutaneous malignant melanoma. Eur J Cancer Prev, 20, 121-2. https://doi.org/10.1097/CEJ.0b013e3283429e1d
  24. Dede DS, Aksoy S, Dizdar O, et al (2010). Blood ABO groups and risk of breast cancer. Med Oncol, 27, 1433. https://doi.org/10.1007/s12032-009-9346-1
  25. Doll R, Swynnerton BF, Newell AC (1960). Observations on blood group distribution in peptic ulcer and gastric cancer. Gut, 1, 31-5. https://doi.org/10.1136/gut.1.1.31
  26. Edgren G, Hjalgrim H, Rostgaard K, et al (2010). Risk of gastric cancer and peptic ulcers in relation to ABO blood type: a cohort study. Am J Epidemiol, 172, 1280-5. https://doi.org/10.1093/aje/kwq299
  27. Egger M, Davey SG, Schneider M, Minder C (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ, 315, 629-34. https://doi.org/10.1136/bmj.315.7109.629
  28. Eisenberg H, Greenberg RA, Yesner R (1958). ABO blood groups and gastric cancer. J Chron Dis, 8, 342-8. https://doi.org/10.1016/0021-9681(58)90200-5
  29. El HI, Hashash JG, Baz EM, Abdul-Baki H, Sharara AI (2007). ABO blood group and gastric cancer: rekindling an old fire? South Med J, 100, 726-7. https://doi.org/10.1097/SMJ.0b013e3180485d24
  30. Engin H, Bilir C, Ustun H, Gokmen A (2012). ABO blood group and risk of pancreatic cancer in a Turkish population in Western Blacksea region. Asian Pac J Cancer Prev, 13, 131-3. https://doi.org/10.7314/APJCP.2012.13.1.131
  31. Erikssen J, Thaulow E, Stormorken H, Brendemoen O, Hellem, A (1980). ABO blood groups and coronary heart disease (CHD). A study in subjects with severe and latent CHD. Thromb Haemost, 43, 137-40.
  32. Gates MA, Wolpin BM, Cramer DW, Hankinson SE, Tworoger, SS (2011). ABO blood group and incidence of epithelial ovarian cancer. Int J Cancer, 128, 482-6. https://doi.org/10.1002/ijc.25339
  33. Gates MA, Xu M, Chen WY, et al (2012). ABO blood group and breast cancer incidence and survival. Int J Cancer, 130, 2129-37. https://doi.org/10.1002/ijc.26220
  34. Glober GA, Cantrell EG, Doll R, Peto R (1971). Interaction between ABO and rhesus blood groups, the site of origin of gastric cancers, and the age and sex of the patient. Gut, 12, 570-3. https://doi.org/10.1136/gut.12.7.570
  35. Gong Y, Yang YS, Zhang XM, et al (2012). ABO blood type, diabetes and risk of gastrointestinal cancer in northern China. World J Gastroenterol, 18, 563-9. https://doi.org/10.3748/wjg.v18.i6.563
  36. Greer JB, Yazer MH, Raval JS, et al (2010). Significant association between ABO blood group and pancreatic cancer. World J Gastroenterol, 16, 5588-91. https://doi.org/10.3748/wjg.v16.i44.5588
  37. Grivennikov SI, Greten FR, Karin M (2010). Immunity, inflammation, and cancer. Cell, 140, 883-99. https://doi.org/10.1016/j.cell.2010.01.025
  38. Hakomori S (1999). Antigen structure and genetic basis of histo-blood groups A, B and O: their changes associated with human cancer. Biochim Biophys Acta, 1473, 247-66. https://doi.org/10.1016/S0304-4165(99)00183-X
  39. Hartmann O, Stavem P (1964). ABO blood-groups and cancer. Lancet, 283, 1305-6. https://doi.org/10.1016/S0140-6736(64)91696-4
  40. Hawkins BR, Simons MJ, Goh EH, Chia KB, Shanmugaratnam K (1974). Immunogenetic aspects of nasopharyngeal carcinoma. II. Analysis of ABO, rhesus and MNSs red cell systems. Int J Cancer, 13, 116-21. https://doi.org/10.1002/ijc.2910130113
  41. Henderson J, Seagroatt V, Goldacre M (1993). Ovarian cancer and ABO blood groups. J Epidemiol Community Health, 47, 287-9. https://doi.org/10.1136/jech.47.4.287
  42. Henry SM, Woodfield DG (1993). A possible relationship between colorectal carcinoma and ABO/Lewis blood groups. Immunohematology, 9, 101-4.
  43. Higgins JP, Thompson SG (2002). Quantifying heterogeneity in a meta-analysis. Stat Med, 21, 1539-58. https://doi.org/10.1002/sim.1186
  44. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003). Measuring inconsistency in meta-analyses. Br Med J, 327, 557-60. https://doi.org/10.1136/bmj.327.7414.557
  45. Holley KE, Taswell HF, Moertel CG (1966). ABO and Rho(D) blood types in patients with multiple primary cancers. JAMA, 198, 1297-8. https://doi.org/10.1001/jama.1966.03110250111029
  46. Hoskins LC, Loux HA, Britten A, Zamcheck N (1965). Distribution of ABO blood groups in patients with pernicious anemia, gastric carcinoma and gastric carcinoma associated with pernicious anemia. N Engl J Med, 273, 633-7. https://doi.org/10.1056/NEJM196509162731204
  47. Jaleel BF, Nagarajappa R (2012). Relationship between ABO blood groups and oral cancer. Indian J Dent Res, 23, 7-10. https://doi.org/10.4103/0970-9290.99029
  48. Joh HK, Cho E, Choueiri TK (2012). ABO blood group and risk of renal cell cancer. Cancer Epidemiol, 36, 528-32. https://doi.org/10.1016/j.canep.2012.07.001
  49. Kamlesh G (2005). ABO blood groups in gastrointestinal tract (GIT) and breast carcinoma patients. Anthropologist, 7, 189-92.
  50. Kaur I, Singh IP, Bhasin MK (1992). Blood groups in relation to carcinoma of cervix uteri. Hum Hered, 42, 324-6. https://doi.org/10.1159/000154091
  51. Khalili H, Wolpin BM, Huang ES, et al (2011). ABO blood group and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev, 20, 1017-20. https://doi.org/10.1158/1055-9965.EPI-10-1250
  52. Klaamas K, Kurtenkov O, Covacci A, Lipping A, Wadstrom, T (1999). Immune response to a recombinant fragment of the CagA protein of Helicobacter pylori in blood donors and patients with gastric cancer: relation to ABO(H) blood group phenotype, stage of the disease and tumor morphology. Med Microbiol Immunol, 187, 227-32. https://doi.org/10.1007/s004300050097
  53. Krokfors E, Kinnunen O (1954). Blood groups and gynaecological cancer. Br Med J, 1, 1305-6. https://doi.org/10.1136/bmj.1.4874.1305
  54. Kurtenkov O, Klaamas K, Miljukhina L (1995). The lower level of natural anti-Thomsen-Friedenreich antigen (TFA) agglutinins in sera of patients with gastric cancer related to ABO(H) blood-group phenotype. Int J Cancer, 60, 781-5. https://doi.org/10.1002/ijc.2910600609
  55. Le Pendu J, Marionneau S, Cailleau-Thomas A, et al (2001). ABH and Lewis histo-blood group antigens in cancer. Apmis, 109, 9-31. https://doi.org/10.1111/j.1600-0463.2001.tb00011.x
  56. Levitan R, Razis DV, Diamond HD, Craver LF (1959). ABO blood groups in Hodgkin's disease. Acta Haematol, 22, 12-9. https://doi.org/10.1159/000205756
  57. Lewis JG, Woods AC (1961). The ABO and Rhesus blood groups in patients with respiratory disease. Tubercle, 42, 362-5. https://doi.org/10.1016/S0041-3879(61)80124-4
  58. Lisker R, Taboada C, Reyes JL (1964). Distribution of the abo blood groups in peptic ulcer, gastric carcinoma and liver cirrhosis in a mexican population. Vox Sang, 9, 202-3. https://doi.org/10.1111/j.1423-0410.1964.tb03681.x
  59. Llopis B, Ruiz JL, Server G, et al (1990). ABO blood groups and bladder carcinoma. Eur Urol, 17, 289-92.
  60. Macafee AL (1967). Blood groups and gastrointestinal cancer. A comparison of the ABO distribution by site of lesion. Ulster Med J, 36, 51-2.
  61. Macmahon B, Folusiak JC (1958). Leukemia and ABO blood group. Am J Hum Genet, 10, 287-93.
  62. Maurer B, Hickey N, Mulcahy R (1969). ABO and Rh blood groups in patients with coronary heart disease. Ir J Med Sci, 8, 105-8.
  63. Melzer D, Perry JR, Hernandez D, et al (2008). A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet, 4, 1000072. https://doi.org/10.1371/journal.pgen.1000072
  64. Miao SY, Zhou W, Chen L, Wang S, Liu XA (2013). Influence of ABO blood group and Rhesus factor on breast cancer risk: A meta-analysis of 9665 breast cancer patients and 244 768 controls. Asia Pac J Clin Oncol, 10, 1-8.
  65. MITRA S, MONDAL S, BASU A (1962). The study of ABO blood groups in cancer of the female genital organs and cancer of the breast. Cancer, 15, 39-41. https://doi.org/10.1002/1097-0142(196201/02)15:1<39::AID-CNCR2820150106>3.0.CO;2-X
  66. Mousseron-Canet MM (1984). Blood groups, sex, and frequency of colorectal carcinoma. Lancet, 2, 926-7.
  67. Nakao M, Matsuo K, Hosono S, et al (2011). ABO blood group alleles and the risk of pancreatic cancer in a Japanese population. Cancer Sci, 102, 1076-80. https://doi.org/10.1111/j.1349-7006.2011.01907.x
  68. Nakao M, Matsuo K, Ito H, et al (2011). ABO genotype and the risk of gastric cancer, atrophic gastritis, and Helicobacter pylori infection. Cancer Epidemiol Biomarkers Prev, 20, 1665-72. https://doi.org/10.1158/1055-9965.EPI-11-0213
  69. Newell GR, Gordon JE, Monlezun AP, Horwitz JS (1974). ABO blood groups and cancer. J Natl Cancer Inst, 52, 1425-30.
  70. Newman E, Naifeh GS, Auer JE, Buckwalter JA (1961). Secretion of ABH antigens in peptic ulceration and gastric carcinoma. BMJ, 1, 92-4. https://doi.org/10.1136/bmj.1.5219.92
  71. Oguz A, Unal D, Tasdemir A, et al (2013). Lack of any association between blood groups and lung cancer, independent of histology. Asian Pac J Cancer Prev, 14, 453-6. https://doi.org/10.7314/APJCP.2013.14.1.453
  72. Osborne RH, DE George FV (1962). The ABO blood groups in parotid and submaxillary gland tumors. Am J Hum Genet, 14, 199-209.
  73. Osborne RH, Degeorge FV (1963). The abo blood groups in neoplastic disease of the ovary. Am J Hum Genet, 15, 380-8.
  74. Parsonnet J, Fridman GD (1997). Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut, 3, 297-301.
  75. Paterson AD, Lopes-Virella MF, Waggott D, et al (2009). Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin. Arterioscler Thromb Vasc Biol, 29, 1958-67. https://doi.org/10.1161/ATVBAHA.109.192971
  76. Pearce KM, Yates PO (1965). Blood groups and brain tumours. J Neurol Sci, 2, 434-41. https://doi.org/10.1016/0022-510X(65)90119-X
  77. Poole EM, Gates MA, High BA, et al (2012). ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium. Cancer Causes Control, 23, 1805-10. https://doi.org/10.1007/s10552-012-0059-y
  78. Qi L, Cornelis MC, Kraft P, et al (2010). Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes. Hum Mol Genet, 19, 1856-62. https://doi.org/10.1093/hmg/ddq057
  79. Qiu MZ, Zhang DS, Ruan DY, et al (2011). A relationship between ABO blood groups and clinicopathologic characteristics of patients with gastric adenocarcinoma in China. Med Oncol, 28, 268-73. https://doi.org/10.1007/s12032-010-9735-5
  80. Reid ME, Mohandas N (2004). Red blood cell blood group antigens: structure and function. Semin Hematol, 41, 93-117.
  81. Rennie HM, Haber RW (1961). Blood groups and carcinoma of the lung. Med J Australia, 48, 323-5.
  82. Risch HA, Lu L, Wang J, et al (2013). ABO blood group and risk of pancreatic cancer: a study in Shanghai and meta-analysis. Am J Epidemiol, 177, 1326-37. https://doi.org/10.1093/aje/kws458
  83. Rizzato C, Campa D, Pezzilli R, et al (2013). ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium. Oncol Rep, 29, 1637-44.
  84. Rizzato C, Kato I, Plummer M, et al (2013). Risk of advanced gastric precancerous lesions in Helicobacter pylori infected subjects is influenced by ABO blood group and cagA status. Int J Cancer, 133, 315-22. https://doi.org/10.1002/ijc.28019
  85. Ronco AL, Stoll M, De Stefani E, et al (2009). Rh factor, family history and risk of breast cancer: a case-control study in Uruguay. Cancer Detect Prev, 32, 277-85. https://doi.org/10.1016/j.cdp.2008.12.005
  86. Roots I, Drakoulis N, Ploch M, et al (1988). Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk. Klin Wochenschr, 66, 87-97. https://doi.org/10.1007/BF01774220
  87. Rotkin ID (1965). Are abo and rh blood groups associated with cancer of the uterine cervix? Cancer, 18, 391-6. https://doi.org/10.1002/1097-0142(196503)18:3<391::AID-CNCR2820180318>3.0.CO;2-S
  88. Segi M, Fujisaku S, Kurihara M, Moniwa H (1957). Cancer of cervix uteri and ABO blood groups. Tohoku J Exp Med, 66, 50. https://doi.org/10.1620/tjem.66.50
  89. Segi M, Fujisaku S, Kurihara M, Moniwa H (1957). Stomach cancer and ABO blood groups. Tohoku J Exp Med, 66, 42. https://doi.org/10.1620/tjem.66.42
  90. Seow LJ, Kwa SB, Teoh CK (1964). A preliminary survey of abo blood group frequency in nasopharyngeal carcinoma in chinese patients. Singapore Med J, 4, 93-5.
  91. Sheng L, Sun X, Zhang L, Su D (2013). ABO blood group and nasopharyngeal carcinoma risk in a population of Southeast China. Int J Cancer, 133, 893-7. https://doi.org/10.1002/ijc.28087
  92. Song HR, Shin MH, Kim HN, et al (2013). Sex-specific differences in the association between ABO genotype and gastric cancer risk in a Korean population. Gastric Cancer , 16, 254-60. https://doi.org/10.1007/s10120-012-0176-z
  93. Strang RR (1965). ABO blood-groups in Parkinson's disease. Acta Pathol Microbiol Scand, 65, 653.
  94. Su M, Lu SM, Tian DP, et al (2001). Relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China. World J Gastroenterol, 7, 657-61.
  95. Takkouche B, Cadarso-Suarez C, Spiegelman D (1999). Evaluation of old and new tests of heterogeneity in epidemiologic meta-analysis. Am J Epidemiol, 150, 206-15. https://doi.org/10.1093/oxfordjournals.aje.a009981
  96. Tanikawa C, Urabe Y, Matsuo K, et al (2012). A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. Nat Genet, 44, 430-4. https://doi.org/10.1038/ng.1109
  97. Urun Y, Ozdemir NY, Utkan G, et al (2012). ABO and Rh Blood Groups and Risk of Colorectal Adenocarcinoma. Asian Pac J Cancer Prev, 13, 6097-100. https://doi.org/10.7314/APJCP.2012.13.12.6097
  98. Urun Y, Utkan G, Altundag K, et al (2012). ABO and Rh blood groups frequency in women with HER2 positive breast cancer. J BUON, 17, 457-60.
  99. Urun Y, Utkan G, Arslan O, et al (2011). Relationship between ABO and RH blood groups and K-ras phenotype in patients with colorectal adenocarcinoma. Eur J Cancer, 471, 432-3.
  100. Urun Y, Utkan G, Yalcin S, et al (2012). Lack of any relationship between ABO and Rh blood groups and clinicopathological features in patients with gastrointestinal stromal tumors: Turkish Oncology Group. Asian Pac J Cancer Prev, 13, 4129-31. https://doi.org/10.7314/APJCP.2012.13.8.4129
  101. Utkan G, Urun Y, Cangir AK, et al (2013). Clinicopathological features of patients with malignant mesothelioma in a multicenter, case-control study: no role for ABO-Rh blood groups. Asian Pac J Cancer Prev, 14, 249-53. https://doi.org/10.7314/APJCP.2013.14.1.249
  102. van Wayjen RG, Linschoten H (1973). Distribution of ABO and rhesus blood groups in patients with gastric carcinoma, with reference to its site of origin. Gastroenterology, 65, 877-83.
  103. Wang DS, Chen DL, Ren C, et al (2012). ABO blood group, hepatitis B viral infection and risk of pancreatic cancer. Int J Cancer, 131, 461-8. https://doi.org/10.1002/ijc.26376
  104. Wang Z, Liu L, Ji J, et al (2012). ABO blood group system and gastric cancer: a case-control study and meta-analysis. Int J Mol Sci, 13, 13308-21. https://doi.org/10.3390/ijms131013308
  105. Williams AO (1966). Haemoglobin genotypes, ABO blood groups, and Burkitt's tumour. J Med Genet, 3, 177-9. https://doi.org/10.1136/jmg.3.3.177
  106. Wolpin BM, Chan AT, Hartge P, et al (2009). ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst, 101, 424-31. https://doi.org/10.1093/jnci/djp020
  107. Wolpin BM, Kraft P, Gross M, et al (2010). Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res, 70, 1015-23. https://doi.org/10.1158/0008-5472.CAN-09-2993
  108. Woo SM, Joo J, Lee WJ, et al (2013). Risk of pancreatic cancer in relation to ABO blood group and hepatitis C virus infection in Korea: a case-control study. J Korean Med Sci, 28, 247-51.
  109. Xie J, Qureshi AA, Li Y, Han J (2010). ABO blood group and incidence of skin cancer. PLoS One, 5, 11972. https://doi.org/10.1371/journal.pone.0011972
  110. Xu WH, Zheng W, Xiang YB, Shu XO (2011). ABO blood type is associated with endometrial cancer risk in Chinese women. Chin J Cancer, 30, 766-71. https://doi.org/10.5732/cjc.011.10305
  111. Yazer MH (2005). What a difference 2 nucleotides make: a short review of ABO genetics. Transfus Med Rev, 19, 200-9. https://doi.org/10.1016/j.tmrv.2005.02.003
  112. Yuzhalin AE, Kutikhin AG (2012). ABO and Rh blood groups in relation to ovarian, endometrial and cervical cancer risk among the population of South-East Siberia. Asian Pac J Cancer Prev, 13, 5091-6. https://doi.org/10.7314/APJCP.2012.13.10.5091

Cited by

  1. ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma vol.15, pp.17, 2014, https://doi.org/10.7314/APJCP.2014.15.17.7459
  2. Association between ABO Genotype and Risk of Hepatocellular Carcinoma in Koreans vol.16, pp.7, 2015, https://doi.org/10.7314/APJCP.2015.16.7.2771
  3. Prognostic role of the ABO blood types in Chinese patients with curatively resected non-small cell lung cancer: a retrospective analysis of 1601 cases at a single cancer center vol.34, pp.3, 2015, https://doi.org/10.1186/s40880-015-0054-2
  4. Association of Histopathological Markers with Clinico-Pathological Factors in Mexican Women with Breast Cancer vol.16, pp.18, 2016, https://doi.org/10.7314/APJCP.2015.16.18.8397
  5. Nonsteroidal anti-inflammatory drugs, statins, and pancreatic cancer risk: a population-based case–control study vol.27, pp.12, 2016, https://doi.org/10.1007/s10552-016-0824-4
  6. ABO blood groups in relation to breast carcinoma incidence and associated prognostic factors in Moroccan women vol.33, pp.7, 2016, https://doi.org/10.1007/s12032-016-0784-2
  7. Epidemiologic characteristics of oral cancer: single-center analysis of 4097 patients from the Sun Yat-sen University Cancer Center vol.35, pp.1, 2016, https://doi.org/10.1186/s40880-016-0078-2
  8. Genetically associated pancreatic diseases vol.12, pp.1, 2017, https://doi.org/10.1007/s11377-016-0124-2
  9. -GalNAc glycosylations. (Germline-encoded natural anti-A/Tn cross-reactive IgM) vol.6, pp.7, 2017, https://doi.org/10.1002/cam4.1079
  10. The role of ABO blood groups in glial neoplasms pp.1360-046X, 2018, https://doi.org/10.1080/02688697.2018.1522415
  11. Position of human blood group O(H) and phenotype-determining enzymes in growth and infectious disease vol.1425, pp.1, 2018, https://doi.org/10.1111/nyas.13694
  12. ABO blood type and risk of hepatocellular carcinoma: a meta-analysis vol.12, pp.9, 2018, https://doi.org/10.1080/17474124.2018.1500174
  13. Risk of GERD-Related Disorders in Obese Patients on PPI Therapy: a Population Analysis vol.28, pp.9, 2018, https://doi.org/10.1007/s11695-018-3246-4
  14. AB0 blood groups and rhesus factor expression as prognostic parameters in patients with epithelial ovarian cancer – a retrospective multi-centre study vol.18, pp.1, 2018, https://doi.org/10.1186/s12885-018-4289-6