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Fish and Prion Diseases

프리온 질환과 어류의 관련성에 관한 연구 동향

  • Kim, Jae-Il (Department of Food Science and Nutrition, Pukyong National University)
  • 김재일 (부경대학교 식품영양학과)
  • Received : 2014.07.24
  • Accepted : 2014.07.28
  • Published : 2014.08.31

Abstract

Transmissible spongiform encephalopathies (TSEs), also termed prion diseases, are a threat to food safety and to human and animal health. Variant Creutzfeldt-Jakob disease (vCJD) in humans is caused by the consumption of meat contaminated with bovine spongiform encephalopathy (BSE, mad cow disease). The BSE epidemic in the United Kingdom was shown to be related with the extensive use of BSE-contaminated meat-and-bone meal (MBM) and bovine offal. Many countries worldwide use MBM, as well as meat from cows, for aquaculture feed. This raises concerns about the safety of farmed fish, a major protein source for humans. The present work reviews recent studies on fish prion protein and the transmissibility of mammalian prion agents to fish, providing insights into the future direction of fish prion research.

Keywords

References

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