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Cerebellar encephalopathy from diminazene aceturate (beneril) toxicity in a dog

  • Han, Donghyun (Section of Small Animal Internal Medicine, Institute of Veterinary Science, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Yoon, Won-Kyoung (Section of Small Animal Internal Medicine, Institute of Veterinary Science, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Hyun, Changbaig (Section of Small Animal Internal Medicine, Institute of Veterinary Science, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • Received : 2013.11.28
  • Accepted : 2014.06.02
  • Published : 2014.09.30

Abstract

A 2-year old castrated male Alaskan malamute was referred with primary complaints of marked anemia, hemeglobinuria and depression. Laboratory tests revealed canine babesiois with severe anemia. The dog was treated by blood transfusion and beneril (diminazene aceturate, 3.5 mg/kg IM). Two days after Beneril injection, the dog suddenly showed ataxia progressing to paresis. MRI revealed irregularly diffused lesions in the cerebellum. The case was tentatively diagnosed as cerebellar encephalopathy caused by diminazene toxicity. The dog successfully recovered following steroid therapy.

Keywords

References

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