Journal of the Korean Society of Physical Medicine (대한물리의학회지)

The Korean Society of Physical Medicine (대한물리의학회)
권호 표지
DOI QR코드

DOI QR Code

Measuring Thresholds of Serum Lipid Level related to Hypertension and Age Using Receiver Operating Characteristic Curve in Korean Adult

  • Kim, Seong-Gil (Department of Physical Therapy, Youngsan University) ;
  • Park, So-Hyun (Department of Physical Therapy, Youngsan University)
  • Received : 2014.06.30
  • Accepted : 2014.08.20
  • Published : 2014.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

PURPOSE: The purpose of this study was to determine the optimal thresholds of serum lipid level related to hypertension according to age in Korean adults. METHODS: In total, 564 adults who visited the health examine center in general hospital were included. The blood pressure and lipid profiles of low density lipoprotein cholesterol(LDL), high density lipoprotein cholesterol (HDL), triglyceride(TG) were measured. Receiver operating characteristic (ROC) curve were used to establish optimal thresholds between blood pressure and lipid profiles. RESULTS: The optimal TG cutoff value were 110.50(mg/dl) in the 18-39 and 81.50(mg/dl) in the 40-59 age group, and optimal cutoff value of LDL were 126.50(mg/dl) in the 40-59 age group and 111.00(mg/dl) in the 60 and over age group. There was a negative correlation between HDL and hypertension, a higher HDL decreased hypertension. The optimal cutoff value of HDL was 49.50(mg/dl) in the 18-39 age group. CONCLUSION: The thresholds of hypertension were lower in LDL and TG with aging. This result indicated that elderly people needs to concern more about their lipid profiles to maintain healthy cardiovascular function.

Keywords

References

  1. Collaboration PS, Lewington S, Whitlock G et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet. 2007;370(1829):1839.
  2. Couillard C, Despres J-P, Lamarche B et al. Effects of endurance exercise training on plasma HDL cholesterol levels depend on levels of triglycerides evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arteriosclerosis, thrombosis, and vascular biology. 2001;21(7):1226-32. https://doi.org/10.1161/hq0701.092137
  3. Eom JS, Lee TR, Park SJ et al. The risk factors of the prehypertension and hypertension of rural inhabitants in chungnam-do. Korean J Nutr. 2008;41(8):742-753.
  4. Jung JL, Lee JH, Kang SJ. The comparison to the health fitness, blood glucose and serum lipids profiles according to obesity level in hypertension patients. Journal of Korea sport research. 2007;18(4):33-40.
  5. Kim CG. Effect of Health Behavior and Obesity Indices on Blood Pressure in 20s Man. Journal of Korean Contens.2011;11(8):231-8. https://doi.org/10.5392/JKCA.2011.11.8.231
  6. Lin SX, Carnethon M, Szklo M et al. Racial/ethnic differences in the association of triglycerides with other metabolic syndrome components: the Multi-Ethnic Study of Atherosclerosis. Metabolic syndrome and related disorders. 2011;9(1):35-40. https://doi.org/10.1089/met.2010.0050
  7. Mann DL, Zipes DP, Libby P et al. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 47.
  8. Martin M, Browner W, Hulley S et al. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361 662 men. The Lancet. 1986;328(8513): 933-36. https://doi.org/10.1016/S0140-6736(86)90597-0
  9. Miller M, Stone NJ, Ballantyne C et al. Triglycerides and cardiovascular disease a scientific statement from the American Heart Association. Circulation. 2011;123 (20):2292-333. https://doi.org/10.1161/CIR.0b013e3182160726
  10. National Cholesterol Education Program. ATP III Guidelines At-A-Glance Quick Desk Reference. 2014. https:// www.nhlbi.nih.gov/guidelines/cholesterol/atglance.pdf
  11. National Institute of Health. The seventh report of the Joint National Committee on prevention, evaluation and treatment of high blood pressure. 2003.
  12. Sander GEGiles TD. Hypertension and lipids: lipid factors in the hypertension syndrome. Current hypertension reports. 2002;4(6):458-63. https://doi.org/10.1007/s11906-002-0026-1
  13. Statistics Korea. Cause of death. 2012. http://kostat.go.kr
  14. Stern S, Behar S, Gottlieb S. Cardiology patient pages. Aging and diseases of the heart. Circulation 108(14):e99-101.
  15. Zweig, M. H., & Campbell, G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clinical chemistry. 1993;39(4):561-77.