Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Prevalence of Abnormal Anal Cytology in HIV-Infected Women: a Hospital-Based Study

  • Published : 2014.08.15
Download PDF
⟨ Previous Next ⟩

Abstract

Background: To study the prevalence of abnormal anal cytology by Papanicolaou (Pap) technique in HIV-infected women who attended a HIV clinic at Prapokklao Hospital, Chanthaburi, Thailand. Materials and Methods: HIV-infected women who attended a HIV clinic at Prapokklao Hospital from March 2013 to February 2014 were recruited for anal Pap smears. Participants who had abnormal results of equally or over "abnormal squamous/glandular cells of undetermined significance" (ASC-US) were classified as abnormal anal cytology. Results: A total of 590 anal Pap smears were performed at HIV clinic of Prapokklao Hospital during the study period. There were only 13 patients who had abnormal Pap tests, which were: 11 ASC-US and 2 HSIL (high grade squamous intraepithelial lesion). The prevalence of abnormal anal Pap smears in HIV-infected women who attended HIV clinic at Prapokklao Hospital was 2.2 percent. Percentage of high risk HPV in patients who had abnormal Pap test was 88.9 (8/9). Conclusions: The prevalence of abnormal anal Papanicolaou smears in HIV-infected women who attended the HIV clinic at Prapokklao hospital was quite low in comparison to the earlier literature.

Keywords

References

  1. Afshar RM, Mollaie HR, Fazlalipour M, Arabzadeh SA (2013). Prevalence and type distribution of human papillomavirus infection using the INNo-Lipa assay, Kerman, Southeast Iran. Asian Pac J Cancer Prev, 14, 5287-91. https://doi.org/10.7314/APJCP.2013.14.9.5287
  2. American Cancer Society (2014). Cancer Facts & Figure ures 2014. Atlanta, Ga: American Cancer Society.
  3. Baranoski AS, Tandon R, Weinberg J, et al (2012). Risk factors for abnormal anal cytology over time in HIV-infected women. AM J Obstet Gynecol, 207, 107.
  4. Chaves EBM, Folgierini H, Capp E, et al (2012). Prevalence of abnormal anal cytology in women infected with HIV. J Med Virol, 84, 1335-9. https://doi.org/10.1002/jmv.23346
  5. Cheng SH, Chu FY, Wang CC, et al (2014). Screening and risk factors for anal cancer precursors in men infected with HIV in Taiwan. J Med Virol, 86, 193-201. https://doi.org/10.1002/jmv.23825
  6. Dona MG, Benevolo M, Vocaturo A, et al (2012). Anal cytological abnormalities and epidemiological correlates among men who have sex with men at risk for HIV-1 infection. BMC Cancer, 12, 476. https://doi.org/10.1186/1471-2407-12-476
  7. Gaisa M, Sigel K, Hand J, Goldstone S (2014). High rates of anal dysplasia in HIV-infected men who have sex with men, women, and heterosexual men. AIDS, 28, 215-22. https://doi.org/10.1097/QAD.0000000000000062
  8. Ghosh I, Ghosh P, Bharti AC, et al (2012). Prevalence of human papillomavirus and co-existent sexually transmitted infections among female sex workers, men having sex with men and injectable drug abusers from eastern India. Asian Pac J Cancer Prev, 13, 799-802. https://doi.org/10.7314/APJCP.2012.13.3.799
  9. Gingelmaier A, Weissenbacher T, Kost B, et al (2010). Anal cytology as a screening tool for early detection of anal dysplasia in HIV-infected women. Anticancer Res, 30, 1719-23.
  10. Greebon LJ, Avery DL, Prihoda TJ, et al (2014). The frequency of herpes simplex virus changes in anal Pap smear and its association with squamous intraepithelial lesions in high-risk male patients. Diagn Cytopathol, 42, 487-90. https://doi.org/10.1002/dc.23006
  11. Hoots BE, Palefsky JM, Pimenta JM, et al (2009). Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions. Int J Cancer, 124, 2375-83. https://doi.org/10.1002/ijc.24215
  12. Kojic EM, Cu-Uvin S, Conley L, et al (2011). Human papillomavirus infection and cytologic abnormalities of the anus and cervix among HIV-infected women in the study to understand the natural history of HIV/AIDS in the era of effective therapy (the SUN study). Sex Transm Dis, 38, 253-9.
  13. Patarapadungkit N, Koonmee S, Pasatung E, et al (2012). Anal cancer screening by modified liquid-based cytology in an HIV clinic. Asian Pac J Cancer Prev, 13, 4487-90. https://doi.org/10.7314/APJCP.2012.13.9.4487
  14. Schim van der Loeff MF, Mooij SH, Richel O, de Vries HJ, Prins JM (2014). HPV and anal cancer in HIV-infected individuals: A Review. Curr HIV/AIDS Rep, 3.
  15. Siegel R, Naishadham D, Jemal A (2012). Cancer statistics, 2012. CA Cancer J Clin, 62, 10-29. https://doi.org/10.3322/caac.20138
  16. Solomon D, Nayar R (2004). The Bethesda system for reporting cervical cytology: definitions, criteria, and explanatory notes.2nd edition. New York: Springer-Verlag New York, Inc.
  17. Suwannarurk K, Tapanadechopol P, Pattaraarchachai J, et al (2009). Hospital-based prevalence and sensitivity of highrisk human papillomavirus in Thai urban population. Cancer Epidemiol, 33, 56-60. https://doi.org/10.1016/j.canep.2009.04.006
  18. Zhang HY, Tiggelaar SM, Sahasrabuddhe VV, et al (2012). HPV prevalence and cervical intraepithelial neoplasia among HIV-infected women in Yunnan Province, China: a pilot study. Asian Pac J Cancer Prev, 13, 91-6. https://doi.org/10.7314/APJCP.2012.13.1.091

Cited by

  1. Anal Papanicolaou Smear in Women with Abnormal Cytology: a Thai Hospital Experience vol.16, pp.3, 2015, https://doi.org/10.7314/APJCP.2015.16.3.1289
  2. Incidence of Anal Dysplasia in a Population of High-Risk Women vol.21, pp.4, 2017, https://doi.org/10.1097/LGT.0000000000000328