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The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Antioxidant Activity of the Seagrass Zostera japonica

애기거머리말의 항산화 활성

  • Kwak, Myoung Kuk (Division of Marine Environment & Bioscience, Korea Maritime & Ocean University) ;
  • Kim, Da Seul (Ocean Science & Technology School, Korea Maritime & Ocean University) ;
  • Oh, Kwang-Suk (Department of Architecture and Ocean Space, Korea Maritime & Ocean University) ;
  • Seo, Youngwan (Division of Marine Environment & Bioscience, Korea Maritime & Ocean University)
  • 곽명국 (한국해양대학교 해양환경.생명과학부) ;
  • 김다슬 (한국해양대학교 해양과학기술융합학과) ;
  • 오광석 (한국해양대학교 해양공간건축학과) ;
  • 서영완 (한국해양대학교 해양환경.생명과학부)
  • Received : 2014.07.12
  • Accepted : 2014.08.20
  • Published : 2014.08.31
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Abstract

In this study, crude extract of the seagrass Zostera japonica, and its solvent-partitioned fractions were evaluated for their antioxidant activity. The crude extract was successively fractionated into n-hexane, 85% aqueous methanol (85% aq.MeOH), n-butanol (n-BuOH), and water fractions by liquid-liquid partition. These include DPPH radical scavenging, hydroxyl radical scavenging in HT-1080 cells, peroxynitrite scavenging, and protective effect on DNA damage caused by hydroxyl radicals generated. In all assays, except for DPPH radical, 85% aq.MeOH and n-BuOH fraction showed the strong antioxidant activity. These results suggest that Z. japonica may be used as a potential source of natural antioxidants for the development of cosmetic product or functional food in the future.

Keywords

References

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