Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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The Verify of Memory Improvement by Gastrodia Elata Blume Depends on the Amount

천마의 용량에 따른 기억력 향상 효과에 대한 연구

  • Kim, Ha-Na (Department of Neuropsychiatry, College of Oriental Medicine, Dong-Shin University) ;
  • Kim, Ji-Eun (Department of Obstetric Gynecology, College of Oriental Medicine, Dong-Shin University) ;
  • Jeong, Jong-Kil (Department of Herbology, College of Oriental Medicine, Dong-Shin University) ;
  • Kim, Jeong-Sang (Department of Anatomy, College of Oriental Medicine, Dong-Shin University) ;
  • Kim, Kyeong-Ok (Department of Neuropsychiatry, College of Oriental Medicine, Dong-Shin University)
  • 김하나 (동신대학교 한의과대학 한방신경정신과학교실) ;
  • 김지은 (동신대학교 한의과대학 한방부인과학교실) ;
  • 정종길 (동신대학교 한의과대학 본초학교실) ;
  • 김정상 (동신대학교 한의과대학 해부학교실) ;
  • 김경옥 (동신대학교 한의과대학 한방신경정신과학교실)
  • Received : 2014.08.27
  • Accepted : 2014.09.15
  • Published : 2014.09.30
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Abstract

Objectives: This study was designed to investigate the dose-dependent effects of Gastrodia elata Blume for memory improvement. Methods: This study was a 12-weeks, double blind, and comparative clinical study. Those who were eligible worked with a group of healthy seniors, all 60 years of age or older. 22 subjects were randomized either to Gastrodia elata Blume powder form that was steeped in hot water or placebo. We measured the faculty of memory by using MMSE-K, Digit Span, Letter Fluency Test, Word List Memory Test, and Trail Making Test, and again after 12 weeks. Results: 1) Neither Gastrodia elata Blume groups nor control have a difference in MMSE-K, Digit Span, Letter Fluency Test, and Trail Making Test. 2) Gastrodia elata Blume group showed significant advances in immediate recall 1 and 2 of Word List Memory Test, and 3 g group show better results than the 4 g group. 3) 4 g Gastrodia elata Blume group showed significant advances in the recognition of Word List Memory Test. Conclusions: The results suggest that positive effects on memory improvement due to Gastrodia elata Blume depend on the amount.

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