References
- Baltz, R.H. and Seno, E.T. 1988. Genetics of Streptomyces fradiae and tylosin biosynthesis. Annu. Rev. Microbiol. 42, 547-574. https://doi.org/10.1146/annurev.mi.42.100188.002555
- Bate, N., Butler, A.R., Gandecha, A.R., and Cundliffe, E. 1999. Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae. Chem. Biol. 6, 617-624. https://doi.org/10.1016/S1074-5521(99)80113-6
- Bussiere, D.E., Muchmore, S.W., Dealwis, C.G., Schluckebier, G., Nienaber, V.L., Edalji, R.P., Walter, K.A., Ladror, U.S., Holzman, T.F., and Abad-Zapatero, C. 1998. Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria. Biochemistry 37, 7103-7112. https://doi.org/10.1021/bi973113c
- Douthwaite, S., Jalava, J., and Jakobsen, L. 2005. Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm. Mol. Microbiol. 58, 613-622. https://doi.org/10.1111/j.1365-2958.2005.04863.x
- Feder, M., Purta, E., Koscinski, L., Cubrilo, S., Maravic, V.G., and Bujnicki, J.M. 2008. Virtual screening and experimental verification to identify potential inhibitors of the ErmC methyltransferase responsible for bacterial resistance against macrolide antibiotics. ChemMedChem. 3, 316-322. https://doi.org/10.1002/cmdc.200700201
- Gandecha, A.R. and Cundliffe, E. 1996. Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. Gene 180, 173-176. https://doi.org/10.1016/S0378-1119(96)00448-9
- Jin, H.J. 1999. ermSF, a ribosomal RNA adenine N6-methyltransferasegene from Streptomyces fradiae, confers MLS(macrolidelincosamidestreptogramin B) resistance to E. coli when it isexpressed. Mol. Cells 9, 252-257.
- Jin, H.J. 2006. Functional role of peptide segment containing 1-25 amino acids in N-terminal end region of ErmSF. Kor. J. Microbiol. 42, 165- 171.
- Jin, H.J. and Yang, Y.D. 2002. Purification and biochemical characterizationof the ErmSF macrolide-lincosamide-streptogramin Bresistance factor protein expressed as a hexahistidine-tagged proteinin Escherichia coli. Protein Expr. Purif. 25, 149-159. https://doi.org/10.1006/prep.2002.1621
- Kamimiya, S. and Weisblum, B. 1988. Translational attenuation control of ermSF, an inducible resistance determinant encoding rRNA N-methyltransferase from Streptomyces fradiae. J. Bacteriol. 170, 1800-1811. https://doi.org/10.1128/jb.170.4.1800-1811.1988
- Kovalic, D., Giannattasio, R.B., Jin, H.J., and Weisblum, B. 1994. 23S rRNA Domain V, a fragment that can be specifically methylated in vitro by the ErmSF (TlrA) methyltransferase. J. Bacteriol. 176, 6992-6998. https://doi.org/10.1128/jb.176.22.6992-6998.1994
- Laemmli, U.K. 1970. Cleavage of structural proteins during theassembly of the head of bacteriophage T. Nature 227, 680-685. https://doi.org/10.1038/227680a0
- Liu, M., Kirpekar, F., Van Wezel, G.P., and Douthwaite, S. 2000. The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA. Mol. Microbiol. 37, 811-820. https://doi.org/10.1046/j.1365-2958.2000.02046.x
- Park, A.K., Kim, H., and Jin, H.J. 2010. Phylogenetic analysis of rRNA methyltransferases, Erm and KsgA, as related to antibiotic resistance. FEMS Microbiol. Lett. 309, 151-162.
- Roberts, M. C., Sutcliffe, J., Courvalin, P., Jensen, L. B., Rood, J., and Seppala, H.1999. Nomenclature for macrolide and macrolidelincosamide- streptogramin B resistance determinants. Antimicrob. Agents Chemother. 43(12), 2823-2830.
- Rosteck, P.R. Jr., Reynolds, P.A., and Hershberger, C.L. 1991. Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport. Gene 102, 27-32. https://doi.org/10.1016/0378-1119(91)90533-H
- Schluckebier, G., Zhong, P., Stewart, K.D., Kavanaugh, T.J., and Abad-Zapatero, C. 1999. The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. J. Mol. Biol. 289, 277-291. https://doi.org/10.1006/jmbi.1999.2788
- Shortridge, V.D., Doern, G.V., Brueggemann, A.B., Beyer, J.M., and Flamm, R.K. 1999. Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995. Clin. Infect. Dis. 29, 1186-1188. https://doi.org/10.1086/313452
- Vester, B. and Douthewaite, S. 1994. Domain V of 23S rRNA containsall the structural elements necessary for recognition by the ErmE methyltransferase. J. Bacteriol. 176, 6999-7004. https://doi.org/10.1128/jb.176.22.6999-7004.1994
- Weisblum, B. 1995. Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. 39, 577-585. https://doi.org/10.1128/AAC.39.3.577
- Yu, L., Petros, A.M., Schnuchel, A., Zhong, P., Severin, J.M., Walter, K., Holzman, T.F., and Fesik, S.W. 1997. Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamidestreptogramin antibiotic resistance. Nat. Struct. Biol. 4, 483-489. https://doi.org/10.1038/nsb0697-483
- Zalacain, M. and Cundliffe, E. 1989. Methylation of 23S rRNA bytlrA(ermSF), a tylosinresistance determinant from Streptomyces fradiae. J. Bacteriol. 171, 4254-4260. https://doi.org/10.1128/jb.171.8.4254-4260.1989
- Zalacain, M. and Cundliffe, E. 1991. Cloning of tlrD, a fourth resistance gene, from the tylosin producer, Streptomyces fradiae. Gene 97, 137-142. https://doi.org/10.1016/0378-1119(91)90021-3