References
- E. Kohl, J. Steinbauer, M. Landthaler, and R. M. Szeimies, Skin ageing, J. Eur. Acad. Dermatol. Venereol., 25, 873 (2011). https://doi.org/10.1111/j.1468-3083.2010.03963.x
- C. C. Zouboulis and E. Makrantonaki, Hormonal therapy of intrinsic aging, Rejuvenation. Res., 15, 302 (2012). https://doi.org/10.1089/rej.2011.1249
- N. Nisar and N. A. Sohoo, Frequency of menopausal symptoms and their impact on the quality of life of women: a hospital based survey, J. Pak. Med. Assoc., 59, 752 (2009).
- J. Calleja-Agius, M. Brincat, and M. Borg, Skin connective tissue and ageing, Best Pract. Res. Clin. Obstet. Gynaecol., 27, 727 (2013). https://doi.org/10.1016/j.bpobgyn.2013.06.004
- D. F. Archer, Postmenopausal skin and estrogen, Gynecol. Endocrinol., 28, 2 (2012).
- Y. Y. Shu and H. I. Maibach, Estrogen and skin: therapeutic options, Am. J. Clin. Dermatol., 12, 297 (2011). https://doi.org/10.2165/11589180-000000000-00000
- L. B. Dunn, M. Damesyn, A. A. Moore, D. B. Reuben, and G. A. Greendale, Does estrogen prevent skin aging? Results from the first national health and nutrition examination survey (NHANES I), Arch. Dermatol., 133, 339 (1997). https://doi.org/10.1001/archderm.1997.03890390077010
- P. G. Sator, M. O. Sator, J. B. Schmidt, H. Nahavandi, S. Radakovic, J. C. Huber, and H. Honigsmann, A prospective, randomized, double-blind, placebo-controlled study on the influence of a hormone replacement therapy on skin aging in postmenopausal women, Climacteric, 10, 320 (2007). https://doi.org/10.1080/13697130701444073
-
E. D. Son, J. Y. Lee, S. Lee, M. S. Kim, B. G. Lee, I. S. Chang, and J. H. Chung, Topical application of 17-
$\beta$ -estradiol increases extracellular matrix protein synthesis by stimulating TGF-$\beta$ signaling in aged human skin in vivo, J. Invest. Dermatol., 124, 1149 (2005). https://doi.org/10.1111/j.0022-202X.2005.23736.x - J. B. M. Schmidt, M. M. Binder, G. M. Demschik, C. M. Bieglmayer, and A. M. Reiner, Treatment of skin aging with topical estrogens, Int. J. Pharm. Compd., 2, 270 (1998).
- C. Kainz, G. Gitsch, J. Stani, G. Breitenecker, M. Binder, and J. B. Schmidt, When applied to facial skin, does estrogen ointment have systemic effects? Arch. Gynecol. Obstet., 253, 71 (1993). https://doi.org/10.1007/BF02768732
- J. Y. Lin, J. A. Tournas, J. A. Burch, N. A. Monteiro-Riviere, and J. Zielinski, Topical isoflavones provide effective photoprotection to skin, Photodermatol. Photoimmunol. Photomed., 24, 61 (2008). https://doi.org/10.1111/j.1600-0781.2008.00329.x
- B. Iovine, M. L. Iannella, F. Gasparri, V. Giannini, G. Monfrecola, and M. A. Bevilacqua, A comparative analysis of the photo-protective effects of soy isoflavones in their aglycone and glucoside forms, Int. J. Mol. Sci., 13, 16444 (2012). https://doi.org/10.3390/ijms131216444
- M. Masilamani, J. Wei, and H. A. Sampson, Regulation of the immune response by soybean isoflavones, Immunol. Res., 54, 95 (2012). https://doi.org/10.1007/s12026-012-8331-5
-
R. L. Jackson, J. S. Greiwe, and R. J. Schwen, Ageing skin: oestrogen receptor
$\beta$ agonists offer an approach to change the outcome, Exp. Dermatol., 20, 879 (2011). https://doi.org/10.1111/j.1600-0625.2011.01362.x -
K. C. Chang, Y. Wang, I. G. Oh, S. Jenkins, L. P. Freedman, C. C. Thompson, J. H. Chung, and S. Nagpal, Estrogen receptor
$\beta$ is a novel therapeutic target for photoaging, Mol. Pharmacol., 77, 744 (2010). https://doi.org/10.1124/mol.109.062877 -
G. G. Kuiper, J. G. Lemmen, B. Carlsson, J. C. Corton, S. H. Safe, P. T. van der Saag, B. van der Burg, and J. A. Gustafsson, Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor
$\beta$ , Endocrinology, 139, 4252 (1998). https://doi.org/10.1210/endo.139.10.6216 - M. T. Patriarca, A. R. Barbosa de Moraes, H. B. Nader, V. Petri, J. R. Martins, R. C. Gomes, and J. M. Soares Jr, Hyaluronic acid concentration in postmenopausal facial skin after topical estradiol and genistein treatment: a double-blind, randomized clinical trial of efficacy, Menopause, 20, 336 (2013).
- A. B. Moraes, M. A. Haidar, J. M. Soares Junior, M. J. Simoes, E. C. Baracat, and M. T. Patriarca, The effects of topical isoflavones on postmenopausal skin: double-blind and randomized clinical trial of efficacy, Eur. J. Obstet. Gynecol. Reprod. Biol., 146, 188 (2009). https://doi.org/10.1016/j.ejogrb.2009.04.007
- P. Walter, S. Green, G. Greene, A. Krust, J. M. Bornert, J. M. Jeltsch, A. Staub, E. Jensen, G. Scrace, M. Waterfield, and P. Chambon, Cloning of the human estrogen receptor cDNA, Proc. Natl. Acad. Sci. USA, 82, 7889 (1985). https://doi.org/10.1073/pnas.82.23.7889
-
S. Ogawa, S. Inoue, T. Watanabe, H. Hiroi, A. Orimo, T. Hosoi, Y. Ouchi, and M. Muramatsu, The complete primary structure of human estrogen receptor
$\beta$ (hER$\beta$ ) and its heterodimerization with ER$\alpha$ in vivo and in vitro, Biochem. Biophys. Res. Commun., 243, 122 (1998). https://doi.org/10.1006/bbrc.1997.7893 - G. Pelletier and L. Ren, Localization of sex steroid receptors in human skin, Histol. Histopathol., 19, 629 (2004).
- M. Saceda, M. E. Lippman, P. Chambon, R. K. Lindsey, M. Puente, and M. B. Martin, Regulation of the estrogen receptor in MCF-7 cells by estradiol, Mol. Endo., 2, 1157 (1988). https://doi.org/10.1210/mend-2-12-1157
-
S. J. Ellison-Zelski, N. M. Solodin, and E. T. Alarid, Repression of ESR1 through actions of estrogen receptor
$\alpha$ and Sin3A at the proximal promoter, Mol. Cell. Biol., 29, 4949 (2009). https://doi.org/10.1128/MCB.00383-09 - M. P. Brincat, Y. M. Baron, and R. Galea, Estrogens and the skin, Climacteric, 8, 110 (2005). https://doi.org/10.1080/13697130500118100
- L. Rittie, S. Kang, J. J. Voorhees, and G. J. Fisher, Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo, Arch. Dermatol., 144, 1129 (2008).
- E. C. Naylor, R. E. Watson, and M. J. Sherratt, Molecular aspects of skin ageing, Maturitas, 69, 249 (2011). https://doi.org/10.1016/j.maturitas.2011.04.011
- F. Vazquez, S. Palacios, N. Aleman, and F. Guerrero, Changes of the basement membrane and type IV collagen in human skin during aging, Maturitas, 25, 209 (1996). https://doi.org/10.1016/S0378-5122(96)01066-3
- M. Brincat, S. Kabalan, J. W. Studd, C. F. Moniz, J. de Trafford, and J. Montgomery, A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman, Obstet. Gynecol., 70, 840 (1987).
- I. M. Braverman, Elastic fiber and microvascular abnormalities in aging skin, Clin. Geriatr. Med., 5, 69 (1989).
- J. L. Bolognia, I. M. Braverman, M. E. Rousseau, and P. M. Sarrel, Skin changes in menopause, Maturitas, 11, 295 (1989). https://doi.org/10.1016/0378-5122(89)90026-1
- R. Punnonen, P. Vaajalahti, and K. Teisala, Local oestriol treatment improves the structure of elastic fibers in the skin of postmenopausal women, Ann. Chir. Gynaecol. Suppl., 202, 39 (1987).
- S. Stevenson and J. Thornton, Effect of estrogens on skin aging and the potential role of SERMs, Clin. Interv. Aging, 2, 283 (2007). https://doi.org/10.2147/CIA.S798
- A. H. Lichtenstein, Soy protein, isoflavones and cardiovascular disease risk, J. Nutr., 128, 1589 (1998).