Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Value of Perfusion Weighted Magnetic Resonance Imaging in the Diagnosis of Supratentorial Anaplastic Astrocytoma

  • Lee, Kyung Mi (Department of Radiology, Seoul National University Bundang Hospital) ;
  • Kim, Eui Jong (Department of Radiology, Kyung Hee University Hospital, School of Medicine, Kyung Hee University) ;
  • Jahng, Geon-Ho (Department of Radiology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University) ;
  • Park, Bong Jin (Department of Neurosurgery, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University)
  • Received : 2014.04.01
  • Accepted : 2014.09.18
  • Published : 2014.09.28
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Abstract

We report perfusion weighted imaging (PWI) findings of nonenhanced anaplastic astrocytoma in a 30-year-old woman. Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the right medial frontal lobe and right genu of corpus callosum, suggesting a low-grade glioma. However, PWI showed increased relative cerebral blood volume, relative cerebral blood flow, and permeability of nonenhanced brain tumor compared with contralateral normal brain parenchyma, suggesting a high-grade glioma. After surgery, final histopathological analysis revealed World Health Organization grade III anaplastic astrocytoma. This case demonstrates the importance of PWI for preoperative evaluation of nonenhanced brain tumors.

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References

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