Journal of Acupuncture Research

  • 제32권4호
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  • Pages.109-118
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  • 2015
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  • 2586-288X(pISSN)
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  • 2586-2898(eISSN)
대한침구의학회 (Korean Acupuncture & Moxibustion Medicine Society)
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수화기제탕 약침액이 노화 흰쥐의 간세포 및 비장세포의 항산화능에 미치는 영향

The Anti-Oxidative Effect of Suhwagije-decoction on the Liver and Spleen Cells of Aged Rats

  • 전종익 (대전대학교 한의과대학 경락경혈학교실) ;
  • 이현진 (대전대학교 한의과대학 경락경혈학교실) ;
  • 김일구 (대전대학교 한의과대학 경락경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 경락경혈학교실)
  • Jeon, Jong Ik (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University) ;
  • Lee, Hyun Jin (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University) ;
  • Kim, Il Gu (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University) ;
  • Yim, Yun Kyoung (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University)
  • 투고 : 2015.11.26
  • 심사 : 2015.12.14
  • 발행 : 2015.12.18
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초록

Objectives : The purpose of this study was to investigate the anti-oxidative effect of Suhwagije-decoction (SGT) pharmacopuncture solution on the liver and spleen cells of aged rats. Methods : The liver and spleen cells of 10, 52, and 72 week old Sprague Dawley (SD) rats were divided into three groups: distilled water (DW), Vit.C, and SGT groups, which were treated with DW, Vit.C and SGT pharmacopuncture solution respectively. The levels of superoxide dismutase (SOD), glutathione (GSH) and nitric oxide (NO) were then measured. Results : 1. Treatment of SGT pharmacopuncture solution significantly decreased NO concentration in spleen cells of 52 week old rats as compared with that of other groups. 2. Treatment of SGT pharmacopuncture solution significantly increased SOD activity in spleen cells of 72 week old rats as compared with that of other groups. Conclusions : Suhwagije-decoction (SGT) pharmacopuncture solution may have an anti-oxidative effect in the spleen cells of aged rats.

키워드

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