Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
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A Pilot Study to Develop Gamrosu, a Modified Fasting Therapy Beverage: Case Series

절식보조음료 감로수(甘露水) 개발을 위한 선행연구: 증례보고

  • Received : 2015.12.01
  • Accepted : 2015.12.03
  • Published : 2015.12.30
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Abstract

Gamrosu is a modified fasting therapy beverage (431 kcal/d). A retrospective observational study was conducted to investigate the detoxification feasibility of Gamrosu. Three cases were reviewed which participants have finished the fasting with Garmrosu for 10 consecutive days. Detoxification profiles of Gamrosu were reviewed at pre- and post-fasting sessions. Post-Gamrosu session, -6.3% of average weight, -6.5% of average body fat mass and -6.6% of average muscle mass were reduced with the nutrition indices being improved. The inflammation indices showed the significant diminished profiles. Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners, however, marginal elevation of total bilirubin and mild ketoacidosis were observed. The indices of oxidative stress decreased and those of antioxidative activity increased. The fatigue scale scores indicated lower scores except insomnia symptom. Taken together, detoxification profiles of Gamrosu were sufficiently feasible and the observed findings should be considered for further clinical studies.

감로수는 궁중음료인 제호탕과 동의보감의 생맥산에서 유래한 절식보조음료이다. 감로수를 이용한 절식요법의 보완과 향후 예정된 임상시험을 위한 임상지표 선정을 위해 정상인 1예, 비만인 1예, 고도비만인 1예를 대상으로 10일간의 절식요법 전, 후로 증례를 관찰하였다. 절식 후 체중은 평균 -6.3%, 체지방은 평균 -6.5%, 근육은 평균 -6.6% 감소하였고, 영양지표에 해당하는 RBC, hemoglobin, hematocrit, T-protein, albumin의 수치는 증가하였고 염증지표에 해당하는 hs- CRP, CRP, ESR, WBC 수치는 감소하였다. 절식 후에도 간기능, 신기능, 전해질수치는 정상수준을 유지하였고, 산화스트레스는 감소하였으며, 항산화력이 증가하는 결과를 나타내었다. 피로도는 절식 전보다 다소 개선되었고, 절식기 동안 불면 이외에 별다른 불편증상을 호소하지 않았다. 다만 혈중 빌리루빈수치 상승, 케톤 증가로 인한 체액의 약산성화는 절식요법을 시행함에 있어 추후 보완해야 할 사안이라 생각된다. 결론적으로 감로수의 디톡스 프로파일은 적합하며 관찰된 결과는 후속연구에 고려될 것이다.

Keywords

References

  1. Kim YS, Shin YW, Lee ES, Cha YY. A study on obese patients through the viewpoint of detoxification therapy. J Orient Rehab Med. 2001 ; 11(2) : 65-73.
  2. Lee MJ. The study of enema therapy as one of the detoxification therapy. J Orient Neuropsychiatry. 2004 ; 15(2) : 23-36.
  3. Wilhelmi de Toledo F, Buchinger A, Burggrabe H, Holz G, Kuhn C, Lischka E, et al. Fasting therapy: an expert panel update of the 2002 consensus guidelines. Forsch Komplementmed. 2013 ; 20(6) : 434-43. https://doi.org/10.1159/000357602
  4. Shin SU, Kim SS, Shin HD. The clinical study on the effect of reduction in body weight and the change of body composition after fasting therapy. J Korean Orient Assoc Study Obes. 2003 ; 3(1) : 25-35.
  5. Lee SB, Keum DH, Lee MJ. The clinical study on protein analysis during fasting therapy period. J Orient Rehab Med. 1996 ; 6(1) : 317-26.
  6. Lee JM, Hong SY. Effects of modified fasting therapy using fermented herbal medicine on changes of body compositions. J Orient Rehab Med. 2011 ; 21(3) : 33-43.
  7. Kim MJ, Hwang JH, Ko HJ, Na HB, Kim JH. Lemon detox diet reduced body fat, insulin resistance, and serum hs-CRP level without hematological changes in overweight Korean women. Nutr Res. 2015 ; 35(5) : 409-20. https://doi.org/10.1016/j.nutres.2015.04.001
  8. Hwang EH, Kim JY. The clinical study of comparison efficacy between the vegetable ferment extract and the spring water in fasting therapy. J Orient Rehab Med. 2004 ; 14(2) : 119-28.
  9. Ji MS, Park MJ, Lee MY, Kim JG, Ko BS. Effect of Jehotang extract on the growth of intestinal bacteria and immunostimulation. Korean J Food Sci Technol. 2006 ; 38(1) : 104-8.
  10. Jeong SH, Kim SI, Sim KH, Jin SY, Kim MH. Antioxidant and antidiabetic activity of Jehotang according to different cooking methods. Korean J Culin Res. 2012 ; 18(5) : 233-42.
  11. Park KJ, Lee MJ, Kang HM, Kim KS, Lee SH, Cho IH. Saeng-Maek-San, a medicinal herb complex, protects liver cell damage induced by alcohol. Biol Pharm Bull. 2002 ; 25(11) : 1451-5. https://doi.org/10.1248/bpb.25.1451
  12. Kim YS, Rye BH, Kim JS. Effect of Wongisaengmaek-san extract on antioxidative and anti-fatigue activity. J Korean Orient Intern Med. 2009 ; 30(1) : 94-106.
  13. Lee JH, Jeong HS, Lim SM, Cho HB, Ma JY, Ko E, et al. Reliability and validity of the fatigue severity scale among university student in South Korea. Korean J Biol Psychiatry. 2013 ; 20(1) : 6-11.
  14. Kim DH, Shin WS, Jung HW, Jung JK, Lee JW, Park WH, et al. Effect of Coffee enema among detoxification therapy on atherosclerosis: one clinical case report. J Orient Rehab Med. 2013 ; 23(2) : 193-9.
  15. Lee SW, Park WH, Cha YY, Kim JY, Ok IS. Clinical research on 4 cases of coffee enema among detoxification therapy effects on rheumatoid arthritis. J Orient Rehab Med. 2003 ; 13(4) : 201-12.
  16. Jung SK, Kim DE, Yu DS, Yeom SR, Song YS, Kwon YD. The retrospective study on modified fasting therapy in inpatients. J Orient Rehab Med. 2008 ; 18(4) : 171-87.
  17. Chung WS, Park HK, Choi HJ, Kim SS. A case report on the jaundice occurred during the modified fasting therapy period: the Gilbert's syndrome. J Soc Korean Med Obes Res. 2011 ; 11(2) : 69-74.
  18. Kim KW, Chung SH, Chung WS. A clinical case study on the changes of body composition and blood chemistry after modified fasting therapy in a patient with obesity. J Soc Korean Med Obes Res. 2010 ; 10(1) : 49-56.
  19. Kim KW, Chung SH, Chung WS. Clinical case series on the changes of body composition and blood chemistry after modified fasting therapy: a retrospective observational study. Doctoral Midterm Dissertation. Seoul: Kyunghee University. 2013.

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