Korean Journal of Psychosomatic Medicine (정신신체의학)

Korean Psychosomatic Society (한국정신신체의학회)
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Risk Factors for Depression of Patients with Tuberculosis in Tuberculosis Specialty Hospital

결핵전문병원에 입원한 결핵환자의 우울증위험인자

  • Wang, Jung-Hyun (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Park, Chul-Soo (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Kim, Bong-Jo (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Lee, Cheol-Soon (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Cha, Boseok (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Lee, So-Jin (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Lee, Dongyun (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Seo, Ji-Yeong (Department of Psychiatry, Gyeongsang National University Hospital) ;
  • Ahn, InYoung (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Baek, Jong Chul (Department of Obstetrics and Gynecology, Gyeongsang National University Hospital) ;
  • Kang, Hyung Seok (Masan National Tuberculosis Hospital) ;
  • Moon, Sung Ho (Department of Thoracic and Cardiovascular Surgery, Gimhae Jungang Hospital)
  • 왕정현 (경상대학교병원 정신건강의학과) ;
  • 박철수 (경상대학교병원 정신건강의학과) ;
  • 김봉조 (경상대학교병원 정신건강의학과) ;
  • 이철순 (경상대학교병원 정신건강의학과) ;
  • 차보석 (경상대학교병원 정신건강의학과) ;
  • 이소진 (경상대학교병원 정신건강의학과) ;
  • 이동윤 (경상대학교병원 정신건강의학과) ;
  • 서지영 (경상대학교병원 정신건강의학과) ;
  • 안인영 (서울대학교병원 정신건강의학과) ;
  • 백종철 (경상대학교병원 산부인과) ;
  • 강형석 (국립마산결핵병원) ;
  • 문성호 (김해중앙병원)
  • Received : 2015.10.19
  • Accepted : 2015.12.12
  • Published : 2015.12.31
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Abstract

Objectives : This study aimed to investigate the risk factors of depression for patients with tuberculosis(TB). Methods : A total of 57 patients with TB were recruited. All participants completed the Becks Depression Inventory-II for evaluating depressive symptoms. The risk factor for depression was analyzed by binary logistic regression analysis. Nomogram was performed for probability of depression. Results : Low body mass index(BMI, OR 0.801, 95% CI 0.65, 0.98), interruption of treatment for TB(OR 5.908, 95% CI 1.19, 29.41), past history of depression(OR 24.653, 95% CI 1.99, 308.44) were associated with increased risk for depression. The calibration curve for predicting probability of survival showed a good agreement between the nomogram and actual observation(Original C-index=0.789, bias corrected C-index=0.754). Conclusions : The result of the present study indicate that low BMI, interruption of treatment for TB, and past history of depression were risk factors for depression in patients with TB. The psychiatric intervention may be needed to prevent depression if the patients with TB have risk factor during treatment for TB.

연구목적 결핵환자 중 우울증 고위험 환자와 저위험 환자의 비교연구를 통해 결핵환자의 우울증 위험요인을 밝히고자 했다. 방 법 57명의 결핵환자를 대상으로 벡 우울 검사 2판을 이용하여 우울증상을 평가하였다. 우울증 고위험군과 저위험군으로 나누어 이분형로지스틱회귀분석 및 계산도표를 작성하였다. 결 과 신체비만지수가 낮아질수록 우울증 고위험군에 속할 위험은 높았다. 결핵치료 임의중단력이 있을 경우 우울증 고위험군에 속할 위험은 6배 높았다. 우울증 과거병력이 있는 경우 우울증 고위험군에 속할 위험은 25배 높았다. Original C-index는 0.789였고 bias corrected C-index는 0.754로 상당한 일치를 보였다. 결 론 낮은 신체비만지수, 결핵치료 임의중단력, 우울증 과거병력은 결핵환자의 우울증 위험요인임을 밝혔다. 이는 결핵환자에 대한 정신건강의학과적 개입 및 치료를 위한 근거자료가 될 것이다.

Keywords

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