Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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Study on the Validation of the Gated Cone-Beam Computed Tomography on Radiation Therapeutic Linear Accelerator

방사선치료용 선형가속기를 이용한 Gated Cone-Beam CT의 유용성 연구

  • Seo, Jeong-Min (Department of Nuclear Engineering, Hanyang University) ;
  • Kim, Chan-Hyeong (Department of Nuclear Engineering, Hanyang University) ;
  • Park, Byoung-Suk (Department of Radiation Oncology, Samsung Medical Center) ;
  • Park, Cheol-Soo (Department of Radiological Science, Hanlym Polytechnic University) ;
  • Jang, Hyon-Chol (Department of Radiological technology, Suseong College) ;
  • Kim, Joung-Dae (Dep. of Preventive Medicine, College of Medicine, Kangwong National University)
  • 서정민 (한양대학교 원자력공학과) ;
  • 김찬형 (한양대학교 원자력공학과) ;
  • 박병석 (삼성서울병원 방사선종양학과) ;
  • 박철수 (한림성심대학교 방사선과) ;
  • 장현철 (수성대학교 방사선과) ;
  • 김정대 (강원대학교 의과대학 예방의학교실)
  • Received : 2015.05.20
  • Accepted : 2015.10.08
  • Published : 2015.10.31
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Abstract

The respiration is one of important factor in the radiation therapy. The existing commercial method of cone-beam computed tomography on LINAC does not consider respiratory motion of patient hence the images are both distorted and inaccurate. In this study, the cone-beam computed tomography images have been reconstructed from back projection radiography of specific phase on breathing cycle which concerned about respiratory movement in radiation therapy. This study investigated how different between cone-beam CT images with and without gating respiratory movement, and this paper provides that guide and implementation of gated cone-beam CT on radiation therapeutic equipment.

환자의 호흡은 방사선치료에서 중요한 인자로 작용한다. 종양을 치료하는 방사선 치료용 선형가속기에서 시행하는 기존의 cone-beam CT에서는 호흡에 의한 움직임이 반영되지 않아 영상에 왜곡이 발생하여 정확하지 못한 영상 정보를 획득하였다. 본 연구는 호흡에 의한 움직임을 고려하고 특정 순간을 포착한 gating을 적용하여 획득한 back projection 영상을 이용하여 cone-beam CT 영상으로 재구성하였으며 기존의 방법과 비교하였다. 기존의 방법은 영상 왜곡도가 400%에 달하였으나, 본 연구에서 시행한 gating을 적용한 cone-beam CT는 약 2%에 불과하였다. 이에 본 연구는 호흡의 움직임을 반영한 영상유도 방사선치료의 방향과 평가 방법을 제시하였다.

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References

  1. Lars Dietrich, Thomas Tucking, Simeon Nill and Uwe Oelfke, "Compensation for respiratory motion by gated radiotherapy", Phys. Med. Biol., Vol. 50, pp. 2405-2414, 2005. DOI: http://dx.doi.org/10.1088/0031-9155/50/10/015
  2. Siewerdsen JH, Daly MJ, Bakhtiar B, Moseley DJ, Richard S, Keller H and Jaffray DA, "A simple, direct method for x-ray scatter estimation and correction in digital radiography and cone-beam CT", Med. Phys., Vol. 33, No.1, pp. 187-197, 2006. DOI: http://dx.doi.org/10.1118/1.2148916
  3. Jan-Jakob Sonke, Lambert Zijp, Peter Remeijer and Marcel van Herk, "Respiratory correlated cone beam CT", Med. Phys. Vol.32, No.4, pp. 1176-1186, 2005. DOI: http://dx.doi.org/10.1118/1.1869074
  4. Ma C.-M. and Paskalev, K., "In-room CT tecnnique for image guided radiation therapy", Med. Dosim. Vol. 31, pp. 30-39, 2006. DOI: http://dx.doi.org/10.1016/j.meddos.2005.12.010
  5. Wong, J.R., Cheng, C.W. and Grimm, L., "Clinical implementation of the world's first Primatom a combination of CT scanner and linear accelerator for precise tumor targeting and treatment", Med. Phys., Vol. 17, pp. 271-276, 2001.
  6. Rohini George, Theodore D. Chung, Sastry S. Vedam, Viswanathan Ramakrishnan, Radhe Mohan, Elisabeth Weiss and Paul J. Keall, "Audio-visual biofeedback for respiratory-gated radiotherapy", Int.J.Radiation Oncol. Biol. Phys., Vol. 65, pp. 924-933, 2006. DOI: http://dx.doi.org/10.1016/j.ijrobp.2006.02.035
  7. Swindell, W., Simpson, R.G., Oleson, J.R., "Computed tomography with a linear accelerator with radiotherapy applications", Med. Phys. Vol. 10, pp. 416-420, 1983. DOI: http://dx.doi.org/10.1118/1.595391
  8. Paul J. Keall, Gig S. Mageras, et al., American Association of Physicists in Medicine, "The Management of Respiratory Motion in Radiation Oncology, Report of AAPM Task Group 76", pp. 7-15, American Association of Physicists in Medicine, 2006.
  9. J. Daniel Bourland, "Image-Guided Radation Therapy", pp. 71-130, CRC Press, 2012
  10. J. Daniel Bourland, "Image-Guided Radation Therapy", pp. 43-70, CRC Press, 2012.
  11. Robert Timmerman, Lei Xing, "Image-Guided and Adaptive Radation Therapy", pp. 3-40, Wolters Kluwer, 2010.
  12. Steven F. Petit, Wouter J. C. van Elmpt, Philippe Lambin, Andre L.A.J. Dekker, "Dose recalculation in megavoltage cone-beam CT for treatment evaluation : Removal of cupping and truncation artefacts in scans of the thorax and abdomen", Radiotherapy and Oncology, Vol 94, pp.359-366, 2010. DOI: http://dx.doi.org/10.1016/j.radonc.2009.12.001
  13. Oliver Morin, Amy gillis, Josephine Chen, "Megavoltage Cone-Beam CT : System Description and Clinical Applications", Medical Dosimetry, Vol 31, No. 1, pp.51-61, 2006. DOI: http://dx.doi.org/10.1016/j.meddos.2005.12.009
  14. Spies L, Ebert M, Groh BA, Hesse BM, Bortfeld T., "Correction of scatter in megavoltage cone-beam CT", Phys Med Biol, Vol. 46, pp. 821-833, 2001. DOI: http://dx.doi.org/10.1088/0031-9155/46/3/316
  15. Verellen D, Ridder MD, Linthout N, Tournel K, Soete G, Storme G., "Innovations in image-guided radiotherapy", Nat Rev Cancer, Vol. 7, pp. 949-960, 2007. DOI: http://dx.doi.org/10.1038/nrc2288
  16. Jeong-Ho Kim, Seok-Hwan Bae, Ki-Jin Kim, Se-Jong Yu, Jee-Yoon Kim, "Analysis of setup error at rectal cancer radiotherapy technique", Jounal of the Korea Academia-Industrial cooperation Society, Vol 14, No. 12, pp.6346-6352, 2013. DOI: http://dx.doi.org/10.5762/KAIS.2013.14.12.6346
  17. Paul J. Keall, Gig S. Mageras, et al., American Association of Physicists in Medicine, "The Management of Respiratory Motion in Radiation Oncology, Report of AAPM Task Group 76", pp. 24-25, American Association of Physicists in Medicine, 2006.
  18. Robert Timmerman, Lei Xing, "Image-Guided and Adaptive Radation Therapy", pp. 191-201, Wolters Kluwer, 2010.