Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
권호 표지
DOI QR코드

DOI QR Code

Lichenoid Dysplasia Misdiagnosed as Oral Lichen Planus: 3-Year Follow-up Case Report

  • Shim, Young-Joo (Department of Orofacial Pain and Oral Medicine, Wonkwang University Daejeon Dental Hospital, Wonkwang Dental Research Institute, Wonkwang University) ;
  • Yoon, Jung-Hoon (Department of Oral and Maxillofacial Pathology, Wonkwang University Daejeon Dental Hospital, Wonkwang Bone Regeneration Research Institute, Wonkwang University)
  • Received : 2015.11.25
  • Accepted : 2015.12.03
  • Published : 2015.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

Lichenoid dysplasia is a lichenoid features with epithelial dysplasia clinically and histopathologically similar to oral lichen planus. It can be clinically mistaken for oral lichen planus, but has histopathologic features of dysplasia and a true malignant predisposition. The clinician should be able to differentiate between oral lichen planus and lichenoid dysplasia for the proper management. We experienced a 75-year-old man with erosive, erythematous lesion on the left buccal mucosa previously diagnosed as oral lichen planus. He underwent surgical excision and the final histopathological result confirmed it to be lichenoid dysplasia with massive candidal infection. We report this case with a review of the related literature.

Keywords

References

  1. Krutchkoff DJ, Eisenberg E. Lichenoid dysplasia: a distinct histopathologic entity. Oral Surg Oral Med Oral Pathol 1985;60:308-315. https://doi.org/10.1016/0030-4220(85)90315-9
  2. Eisenberg E, Krutchkoff DJ. Lichenoid lesions of oral mucosa. Diagnostic criteria and their importance in the alleged relationship to oral cancer. Oral Surg Oral Med Oral Pathol 1992;73:699-704. https://doi.org/10.1016/0030-4220(92)90013-G
  3. Kramer IR, Lucas RB, Pindborg JJ, Sobin LH. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol 1978;46:518-539. https://doi.org/10.1016/0030-4220(78)90383-3
  4. van der Meij EH, van der Waal I. Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications. J Oral Pathol Med 2003;32:507-512. https://doi.org/10.1034/j.1600-0714.2003.00125.x
  5. Eisenberg E, Murphy GF, Krutchkoff DJ. Involucrin as a diagnostic marker in oral lichenoid lesions. Oral Surg Oral Med Oral Pathol 1987;64:313-319. https://doi.org/10.1016/0030-4220(87)90011-9
  6. Chi AC. Epithelial pathology. In: Neville BW, Damm DD, Allen CM, Bouquot JE, eds. Oral and maxillofacial pathology. 3rd ed. Philadelphia: W.B. Saunders Co.; 2008. pp. 388-397.
  7. [No authors listed]. Henri Hallopeau (1842-1919). JAMA 1969;207:2431-2432. https://doi.org/10.1001/jama.1969.03150260091016
  8. Krogh P, Holmstrup P, Thorn JJ, Vedtofte P, Pindborg JJ. Yeast species and biotypes associated with oral leukoplakia and lichen planus. Oral Surg Oral Med Oral Pathol 1987;63:48-54. https://doi.org/10.1016/0030-4220(87)90339-2
  9. El Naggar AK, Reichart PA. Proliferative verrucous leukoplakia and precancerous conditions In: Barners L, Eveson JW, Reichart PA, Sidransky D, eds. Pathology and genetics head and neck tumours. Lyon: IARC Press; 2005. pp. 180-181.
  10. Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis 2008;14:229-243. https://doi.org/10.1111/j.1601-0825.2008.01441.x
  11. Fitzpatrick SG, Hirsch SA, Gordon SC. The malignant transformation of oral lichen planus and oral lichenoid lesions: a systematic review. J Am Dent Assoc 2014;145:45-56. https://doi.org/10.14219/jada.2013.10
  12. Scully C. Oral and maxillofacial medicine: the basis of diagnosis and treatment. 2nd ed. Philadelphia: Elsevier; 2008. pp. 191-200.
  13. Greenberg MS, Click M, Ship JA. Burket's oral medicine. 11th ed. Hamilton: BC Decker; 2008. pp. 80-81.
  14. Hebbar PB, Pai A, D S. Mycological and histological associations of Candida in oral mucosal lesions. J Oral Sci 2013;55:157-160. https://doi.org/10.2334/josnusd.55.157
  15. Mohd Bakri M, Mohd Hussaini H, Rachel Holmes A, David Cannon R, Mary Rich A. Revisiting the association between candidal infection and carcinoma, particularly oral squamous cell carcinoma. J Oral Microbiol 2010;2. doi: 10.3402/jom.v2i0.5780.
  16. Wight AJ, Ogden GR. Possible mechanisms by which alcohol may influence the development of oral cancer: a review. Oral Oncol 1998;34:441-447. https://doi.org/10.1016/S1368-8375(98)00022-0
  17. Hashibe M, Brennan P, Benhamou S, et al. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. J Natl Cancer Inst 2007;99:777-789. https://doi.org/10.1093/jnci/djk179
  18. Baan R, Straif K, Grosse Y, et al; WHO International Agency for Research on Cancer Monograph Working Group. Carcinogenicity of alcoholic beverages. Lancet Oncol 2007;8:292-293. https://doi.org/10.1016/S1470-2045(07)70099-2
  19. Secretan B, Straif K, Baan R, et al; WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens--part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 2009;10:1033-1034. https://doi.org/10.1016/S1470-2045(09)70326-2
  20. Nieminen MT, Uittamo J, Salaspuro M, Rautemaa R. Acetaldehyde production from ethanol and glucose by non-Candida albicans yeasts in vitro. Oral Oncol 2009;45:e245-e248. https://doi.org/10.1016/j.oraloncology.2009.08.002