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Prevalence of Esophageal Cancer in the Northern Part of Afghanistan

  • Published : 2015.01.22

Abstract

Background: Esophagogastroduodenoscopy (EGD) is the standard technique for diagnosis of patients presenting with upper gastrointestinal symptoms. Some reports have shown high prevalence of esophageal cancer in the northern part of Afghanistan. The aim of this study was to investigate epidemiological profile of esophageal cancer among patients in this region. Materials and Methods: We identified 364 consecutive patients that received EGD examinations to examine upper gastrointestinal tract at the endoscopy unit of Balkh regional Hospital from March 2012 to March 2013. The case subjects included both in-patients and out-patients aged 16 years or more. We evaluated the results retrospectively. Results: The cases consisted of 184 (51%) males and 180 (49%) females. The mean age was $47.3{\pm}17.8$ and the age range 17-88 years. Ninety two cases had esophageal cancer, out of which 58 (63.0%) were male. The mean age at time of diagnosis was $57.8{\pm}13.2years$. Uzbek-Turkmen peoples were more common among patients with esophageal cancer (52.2%). Dysphagia was the most frequent symptom among patients with esophageal cancer at the time of presentation, seen in 77 (84.8%) of cases. Conclusions: Our results showed high incidence of esophageal cancer in the northern part of Afghanistan, especially in the Uzbek-Turkmen ethnic group.

Keywords

References

  1. Alidina A, Gaffar A, Hussain F, et al (2004). Survival data and prognostic factors seen in Pakistani patients with esophageal cancer. Ann Oncol, 15, 118-22. https://doi.org/10.1093/annonc/mdh014
  2. Amani F, Ahari SS, Akhghari L (2013). Epidemiology of esophageal cancer in Ardabil Province during 2003-2011. Asian Pac J Cancer Prev, 14, 4177-80. https://doi.org/10.7314/APJCP.2013.14.7.4177
  3. Bartsch H (2000). Studies on biomarkers in cancer etiology and prevention: a summary and challenge of 20 years of interdisciplinary research. Mutat Res, 462, 255-79. https://doi.org/10.1016/S1383-5742(00)00008-9
  4. Bloomfeld RS, Bridgers DI 3rd, Pineau BC (2005). Sensitivity of upper endoscopy in diagnosing esophageal cancer. Dysphagia, 20, 278-82. https://doi.org/10.1007/s00455-005-0025-x
  5. Castellsague X, Munoz N, De Stefani E, et al (2000). Influence of mate drinking, hot beverages and diet on esophageal cancer risk in South America. Int J Cancer, 88, 658-64. https://doi.org/10.1002/1097-0215(20001115)88:4<658::AID-IJC22>3.0.CO;2-T
  6. Chan YM, Goh KL (2004). Appropriateness and diagnostic yield of EGD: a prospective study in a large Asian hospital. Gastrointest Endosc, 59, 517-24. https://doi.org/10.1016/S0016-5107(04)00002-1
  7. De Jong UW, Breslow N, Hong JG, Sridharan M, Shanmugaratnam K (1974). Etiological factors in oesophageal cancer in Singapore Chinese. Int J Cancer, 13, 291-03. https://doi.org/10.1002/ijc.2910130304
  8. Ganesh B, Talole SD, Dikishit R (2009). Tobacco, alcohol and tea drinking as risk factors for esophageal cancer: A case control study from Mumbai, India. Cancer Epidemiol, 33, 431-4. https://doi.org/10.1016/j.canep.2009.09.002
  9. Ghavamzadah A, Moussavi A, Jahani M, Rastegarpanah M, Iravani M (2001). Esophageal cancer in Iran. Semin Oncol, 28, 153-7. https://doi.org/10.1016/S0093-7754(01)90086-7
  10. Ghazzawi I, Oweis S, Ajlouni Y (2004). Upper gastrointestinal endoscopy in Jordanian field hospital in Afghanistan. JRMC, 11, 62-4.
  11. Hecht SS (2001). Carcinogenesis biomarkers for lung or oral cancer chemoprevention trials. IARC Sci Publ, 154, 245-55.
  12. Igissinov S, Igissinov N, Moore MA, Kalieva Z, Kozhakhmetov S (2012). Epidemiology of esophageal cancer in Kazakhstan. Asian Pac J Cancer Prev, 13, 833-6. https://doi.org/10.7314/APJCP.2012.13.3.833
  13. Igissinov S, Igissinov N, Moore MA, et al (2013). Component analysis of esophageal cancer incidence in Kazakhstan. Asian Pac J Cancer Prev, 14, 1945-9. https://doi.org/10.7314/APJCP.2013.14.3.1945
  14. Islami F, Kamanger F, Aghcheli K, et al (2004). Epidemiological features of upper gastrointestinal tract cancers in Northeastern Iran. Br J Cancer, 90, 1402-6. https://doi.org/10.1038/sj.bjc.6601737
  15. Islami F, Pourshams A, Kamanger F, et al (2009). Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study. BMJ, 338, 929. https://doi.org/10.1136/bmj.b929
  16. Kamangar F, Malekzadeh R, Dawsey SM, Saidi F (2007). Esophageal cancer in northern Iran: a review. Arch Iranian Med, 10, 70-82.
  17. Kamanger F, Chow WH, Abnet CC, Dawsey SM (2009). Environmental causes of esophageal cancer. Gatroenterol Clin North Am, 38, 27-57. https://doi.org/10.1016/j.gtc.2009.01.004
  18. Kaiser HE (1967). Cancer-promoting effects of phenols in tea, 20, 614-6 https://doi.org/10.1002/1097-0142(1967)20:5<614::AID-CNCR2820200506>3.0.CO;2-N
  19. Kairakbaev MK (1978). Malignant neoplasms among ethnic groups in the Kazak SSR. Vopr Onkol, 24, 100-4.
  20. Kiadaliri AA (2014). Gender and social disparities in esophagus cancer incidence in Iran, 2003-2009: a time trend province-level study. Asian Pac J Cancer Prev, 15, 623-7. https://doi.org/10.7314/APJCP.2014.15.2.623
  21. Launoy G, Milan C, Day NE, et al (1997). Oesophageal cancer in France: potential importance of hot alcoholic drink. Int J Cancer, 71, 917-23. https://doi.org/10.1002/(SICI)1097-0215(19970611)71:6<917::AID-IJC1>3.0.CO;2-0
  22. Maaroos HI, Andreson H, Loivukene K, et al (2004). The diagnostic value of endoscopy and helicobacter pylori tests for peptic ulcer patients in late post-treatment setting. BMC Gastroentrology, 4, 27. https://doi.org/10.1186/1471-230X-4-27
  23. Mansour-Ghanaei F, Heidarzadeh A, Naghipour MR, et al (2012). A 10-year study of esophageal cancer in Guilan province, Iran: the Guilan Cancer Registry Study (GCRS). Asian Pac J Cancer Prev, 13, 6277-83. https://doi.org/10.7314/APJCP.2012.13.12.6277
  24. Marjani HA, Biramijamal F, Hossein-Nezhad A, et al (2010). Prevalence of esophageal cancer risk factors among Turkmen and Non-Turkmen ethnic groups in high incidence area in Iran. Arch Iranian Med, 3, 111-5.
  25. Mashhadi MA, Nazem K, Bakhshipour AR, Ttorbati TF, Ansarimoghaddam AR (2011). High prevalence of esophageal cancer in South East of Iran. IJHOSCR, 5, 18-21.
  26. McColl K, Murray LS, Gillen D, et al (2002). Randomised trial of endoscopy with testing for Helecobacter pylori compared with non-invasive H pylori testing alone in the management of dyspepsia. BMJ, 324, 999-1002. https://doi.org/10.1136/bmj.324.7344.999
  27. Melhado RE, Alderson D, Tucker O (2010). The changing face of esophageal cancer. Cancers, 2, 1379-04. https://doi.org/10.3390/cancers2031379
  28. Mir MM, Dar NA (2009). Esophageal cancer in Kashmir (India): an enigma for researchers. Int J Health Sci, 3, 71-85.
  29. Nguyen VX, Le Nguyen VT, Nguyen CC (2010). Appropriate use of endoscopy in the diagnosis and treatment of gastrointestinal diseases: up-to-date indications for primary care providers. Int J Gen Med, 3, 345-57.
  30. Qureshi NA, Hallissey MT, Fielding JW (2007). Outcome of index upper gastrointestinal endoscopy in patients presenting with dysphagia in a tertiary care hospital-A 10 years review. BMC Gastroenterol, 7, 43. https://doi.org/10.1186/1471-230X-7-43
  31. Rasousli M, Ghadimi MR, Mahmoodi M, et al (2011). Survival analysis of patients with esophageal cancer using parametric curve model. Asian Pac J Cancer Prev, 12, 2359-63.
  32. Saenko AI, (1975). The epidemiology of cancer in Central Asia. Vopr Onkol, 21, 40-4.
  33. Sadjadi A, Marjani H, Semnani S, Nasseri-Moghaddam S (2010). Esophageal cancer in Iran: a review. Mid East J Cancer, 1, 5-14.
  34. Sephehr A, Taniere P, Martel-Planche G, et al (2001). Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophageal in Iran. Oncogene, 20, 7368-74. https://doi.org/10.1038/sj.onc.1204912
  35. Sobin LH (1969). Cancer in Afghanistan. Cancer, 3, 678-88.
  36. Wang JM, Xu B, Rao JY, et al (2007). Diet habits, alcohol drinking, tobacco smoking, green tea drinking, and the risk of esophageal squamous cell carcinoma in the Chinese population. Eur J Gastroenterol Hepatol, 19, 171-6. https://doi.org/10.1097/MEG.0b013e32800ff77a
  37. Zaridze DG, Bsieva T.Kabulov M, Day NE, Duffy SW (1992). Oesophageal cancer in the Republic of Karakalpakstan. Int J Epidemiol, 21, 643-8. https://doi.org/10.1093/ije/21.4.643