Parasites, Hosts and Diseases

  • 제53권6호
  • /
  • Pages.785-788
  • /
  • 2015
  • /
  • 2982-5164(pISSN)
  • /
  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
권호 표지
DOI QR코드

DOI QR Code

Surgical and Molecular Evaluation of Pediatric Hydatid Cyst Cases in Eastern Turkey

  • Bakal, Unal (Department of Pediatric Surgery, Faculty of Medicine, University of Firat) ;
  • Simsek, Sami (Department of Parasitology, Faculty of Veterinary Medicine, University of Firat) ;
  • Kazez, Ahmet (Department of Pediatric Surgery, Faculty of Medicine, University of Firat)
  • 투고 : 2015.07.14
  • 심사 : 2015.10.06
  • 발행 : 2015.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Cystic echinococcosis (CE) caused by Echinococcus granulosus is a major public health problem worldwide, including Turkey. The aim of the current study was to identify the strains and to estimate the potential risk factors of E. granulosus in operated pediatric cases in eastern Turkey. Ten pediatric patients (7 boys and 3 girls) living in rural areas, with ages ranging from 3 to 15 years old and various clinical histories, were included in this study. Eight patients had only liver hydatid cyst, while 1 patient had liver and lung hydatid cyst and the other liver, lung, and spleen, together. There were 2 ruptured liver cysts. After surgery, during follow-up, no increase was observed in hemagglutination levels, there were no mortalities, and there was no evidence of recurrence at 2 years post operation in all patients. Molecular analysis was performed on hydatid cyst samples obtained from the 10 pediatric cases. According to mt-12S rRNA PCR results, all cases were found to be G1/G3 cluster of E. granulosus sensu stricto.

키워드

참고문헌

  1. Thompson RCA. Biology and systematics of Echinococcus. In Thompson RCA, Lymbery AJ, eds, Echinococcus and hydatid disease. Wallingford, UK. CAB International. 1995, pp 1-50.
  2. Grosso G, Gruttadauria S, Biondi A, Marventano S, Mistretta A. Worldwide epidemiology of liver hydatidosis including the Mediterranean area. World J Gastroenterol 2012; 18: 1425-1437. https://doi.org/10.3748/wjg.v18.i13.1425
  3. Craig PS, McManus DP, Lightowlers MW, Chabalgoity JA, Garcia HH, Gavidia CM, Gilman RH, Gonzalez AE, Lorca M, Naquira C, Nieto A, Schantz PM. Prevention and control of cystic echinococcosis. Lancet Infect Dis 2007; 7: 385-394. https://doi.org/10.1016/S1473-3099(07)70134-2
  4. Bryan RT, Schantz PM. Echinococcosis (hydatid disease). J Am Vet Med Assoc 1989; 195: 1214-1217.
  5. Bakal U, Kazez A, Akyol M, Kocakoc E, Simsek S. A portable ultrasound based screening study on the prevalence and risk factors of Cystic Echinococcosis in primary school children in east Turkey. Acta Tropica 2012; 123: 91-95. https://doi.org/10.1016/j.actatropica.2012.03.011
  6. Snabel V, Altintas N, D’Amelio S, Nakao M, Romig T, Yolasigmaz A, Gunes K, Turk M, Busi M, Huttner M, Sevcova D, Ito A, Altintas N, Dubinsky P. Cystic echinococcosis in Turkey: Genetic variability and first record of the pig strain (G7) in the country. Parasitol Res 2009; 105: 145-154. https://doi.org/10.1007/s00436-009-1376-2
  7. Simsek S, Balkaya I, Ciftci AT, Utuk AE. Molecular discrimination of sheep and cattle isolates of Echinococcus granulosus by SSCP and conventional PCR in Turkey. Vet Parasitol 2011a; 178: 367-369. https://doi.org/10.1016/j.vetpar.2011.01.033
  8. Simsek S, Kaplan M, Ozercan IH. A comprehensive molecular survey of Echinococcus granulosus in formaline fixed paraffin embedded tissues in human isolates in Turkey. Parasitol Res 2011b; 109: 411-419. https://doi.org/10.1007/s00436-011-2269-8
  9. Simsek S, Cevik A. First detection and molecular characterization of Echinococcus equinus in a mule in Turkey. Acta Parasitol 2014; 59: 773-777.
  10. Dinkel A, Njoroge EM, Zimmermann A, Walz M, Zeyhle E, Elmahdi IE, Mackenstedt U, Romig T. A PCR system for detection of species and genotypes of the Echinococcus granulosus complex, with reference to the epidemiological situation in eastern Africa. Int J Parasitol 2004; 34: 645-653. https://doi.org/10.1016/j.ijpara.2003.12.013
  11. McManus DP, Zhang W, Li J, Bartley PB. Echinococcosis. Lancet 2003; 362: 1295-1304. https://doi.org/10.1016/S0140-6736(03)14573-4
  12. Mirshemirani A, Razavi S, Sadeghian S. Surgical treatment of pulmonary hydatid cyst in 72 children. Tanaffos 2009; 8: 56-61.
  13. Santivanez S, Garcia HH. Pulmonary cystic echinococcosis. Curr Opin Pulm Med 2010; 16: 257-61.
  14. Aslanabadi S, Zarrintan S, Abdoli-Oskouei S, Salehpour F, Zarrintan A, Beheshtirouy, S, Abdollahi H, Badebarin D. Hydatid cyst in children: A 10-year experience from Iran. African J Paediatric Surg. 2013; 10: 140-144. https://doi.org/10.4103/0189-6725.115040
  15. Montazeri V, Sokouti M, Rashidi HR. Comparison of pulmonary hydatid disease between children and adult. Tanaffos 2007; 6 :13-18.
  16. Talaiezadeh A, Maraghi S. Hydatid disease in children: A different pattern than adults. Pakistan J Med Sci 2006; 22: 329-332.
  17. Dopchiz MC, Elissondo MC, Andresiuk MV, Maiorini E, Gutierrez AM, Muzulin PM, Rosenzvit MC, Lavallen CM, Denegri G. Pediatric hydatidosis in the south-east of the Buenos Aires province, Argentina. Rev Arg Microbiol 2009; 41: 105-111
  18. Giorgio A, Di Sarno A, de Stefano G, Liorre G, Farella N, Scognamiglio U, Giorgio V. Sonography and clinical outcome of viable hydatid liver cysts treated with double percutaneous aspiration and ethanol injection as first-line therapy: efficacy and long-term follow-up. AJR Am J Roentgenol 2009; 193: W186-192. https://doi.org/10.2214/AJR.08.1518
  19. Thompson RCA, McManus DP. Aetiology: parasites and life-cycles. In: WHOO/OIE Manual on Echinococcosis in Humans and Animals: A Public Health Problem of Global Concern (Eckert J, Gemmell M, Meslin F-X, Pawlowski Z eds.) Paris: World Organization for Animal Health. 2001, pp 1-19.
  20. Utuk AE, Simsek S, Koroglu E, McManus DP. Molecular genetic characterization of different isolates of Echinococcus granulosus in east and southeast regions of Turkey. Acta Trop 2008; 107: 192-194. https://doi.org/10.1016/j.actatropica.2008.05.026

피인용 문헌

  1. Cystic Echinococcosis in the Mediterranean vol.4, pp.4, 2017, https://doi.org/10.1007/s40475-017-0129-z
  2. A study to assess the awareness of risk factors of cystic echinococcosis in Turkey vol.39, pp.3, 2018, https://doi.org/10.15537/smj.2018.3.21771
  3. Human cystic echinococcosis in Turkey: a preliminary study on DNA polymorphisms of hydatid cysts removed from confirmed patients vol.117, pp.4, 2015, https://doi.org/10.1007/s00436-018-5807-9
  4. Molecular survey on cattle and sheep hydatidosis and first detection ofEchinococcus canadensis(G6/G7) in sheep in Turkey vol.147, pp.9, 2015, https://doi.org/10.1017/s0031182020000785
  5. Investigation of the relationship between CE cyst characteristics and genetic diversity of Echinococcus granulosus sensu lato in humans from Turkey vol.147, pp.14, 2015, https://doi.org/10.1017/s0031182020001535
  6. Human and animal cystic echinococcosis in Konya, Turkey: molecular identification and the first report of E. equinus from human host in Turkey vol.120, pp.2, 2021, https://doi.org/10.1007/s00436-021-07050-w
  7. Echinococcoses in Iran, Turkey, and Pakistan: Old Diseases in the New Millennium vol.34, pp.3, 2015, https://doi.org/10.1128/cmr.00290-20
  8. Genetic diversity and haplotypes of paediatric hydatid cyst isolates and first occurrence of E. canadensis (G6/G7) in paediatric cases in Turkey vol.148, pp.12, 2021, https://doi.org/10.1017/s0031182021001098