DOI QR코드

DOI QR Code

Differentiation of Canine Calcium Oxalate and Canine Struvite Stones using Computed Tomography

개에서 전산화단층촬영을 이용한 Calcium Oxalate결석과 Struvite결석의 감별

  • Yoon, Young-Min (Institute of Animal Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, Gyeongsang National University)
  • 윤영민 (경상대학교 동물의학연구소) ;
  • 이희천 (경상대학교 동물의학연구소)
  • Accepted : 2015.02.14
  • Published : 2015.02.28

Abstract

This study was performed to differentiate calcium oxalate and struvite canine urinary stones using computed tomography. A total of 38 urinary stones (8 calcium oxalate and 30 struvite) were scanned using a computed tomography scanner. These urinary stones (10-15 mm diameter) extracted surgically without fragmentation were obtained from the different individual patients. The stone's Hounsfield units(HU) values, heterogenicity, and roughness of surface were evaluated to differentiate calcium oxalate and struvite. The HU values of calcium oxalate were significantly higher than those of struvite. A receiver operator characteristic (ROC) curve revealed 1272 as the best threshold value to distinguish calcium oxalate from struvite (ROC curve AUC 0.87, p < 0.0014). The heterogenicity of calcium oxalate and struvite significantly differed on bone and dental window setting (p < 0.0001). There was no significant difference between calcium oxalate and struvite in roughness of surface. On computed tomographic images, bone and dental windows setting were useful for evaluation of heterogenicity between calcium oxalate and struvite. The HU value and heterogenicity are highly promising factor that can distinguish calcium oxalate and struvite with reasonable accuracy.

Keywords

References

  1. Deveci S, Co kun M, Tekin M , Pe kircioglu L, Tarhan N , Ozkarde H. Spiral computed tomography: Role in determination of chemical compositions of pure and mixed urinary stones-an in vitro study. Urology 2004; 64: 237-240. https://doi.org/10.1016/j.urology.2004.03.029
  2. Duan X, Qu M, Wang J, Trevathan J, Vrtiska T, Williams Jr JC, et al. Differentiation of calcium oxalate monohydrate and calcium oxalate dihydrate stones using quantitative morphological information from micro-computerized and clinical computerized tomography. J Urol 2013; 189: 2350-2356. https://doi.org/10.1016/j.juro.2012.11.004
  3. El-Assmy A, Abou-El-Ghar ME, El-Nahas AR, Refaie HF, Sheir KZ. Multidetector computed tomography: Role in determination of urinary stones composition and disintegration with extracorporeal shock wave lithotripsy-an in vitro study. Urology 2011; 77: 286-290. https://doi.org/10.1016/j.urology.2010.05.021
  4. Ettinger SJ, Feldman EC. Urinary system. In: Text book of veterinary internal medicine, 7th ed. St. Louis: W.B. Saunders. 2010; 2088-2108.
  5. Joseph P, Mandal A, Singh S, Mandal P, Sankhwar S, Sharma S. Computerized tomography attenuation value of renal calculus: Can it predict successful fragmentation of the calculus by extracorporeal shock wave lithotripsy? A preliminary study. J Urol 2002; 167: 1968-1971. https://doi.org/10.1016/S0022-5347(05)65064-1
  6. Mostafavi MR, Ernst RD, Saltzman B. Accurate determination of chemical composition of urinary calculi by spiral computerized tomography. J Urol 1998; 159: 673-675. https://doi.org/10.1016/S0022-5347(01)63698-X
  7. Motley G, Dalrymple N, Keesling C, Fischer J, Harmon W. Hounsfield unit density in the determination of urinary stone composition. Urology 2001; 58: 170-173. https://doi.org/10.1016/S0090-4295(01)01115-3
  8. Nelson, RW, Couto CG, Canine urolithiasis. In: Small animal internal medicine, 2nd ed. St. Louis: Mosby. 1998; 638.
  9. Osbome CA, Lulich JP, Unger LK, Bartges JW, Felice LJ. Canine and feline urolithiasis: relationship of etiopathogenesis with treatment and prevention. In: Disease mechanisms in small animal surgery, 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 1993: 464-511.
  10. Thrall DE. The abdominal cavity: canine and feline. In: Textbook of veterinary diagnostic radiology, 6nd ed. St.Louis: Saunders. 2012; 731.