DOI QR코드

DOI QR Code

해부학적 구조를 이용한 유전자 정보 통합 기법

Integration Scheme of Gene Information based on Anatomical Structure

  • 양기철 (목포대학교, 멀티미디어공학과)
  • Yang, Gi-Chul (Department of Multimedia Engineering, Mokpo National University)
  • 투고 : 2014.11.15
  • 심사 : 2015.02.20
  • 발행 : 2015.02.28

초록

생물학자들은 특정 암이나 선천성 질병을 이해하는데 핵심정보를 제공할 수 있는 유전자관련 연구를 진행하고 있다. 하지만 생물학적 실험은 실험당시의 여러 가지 요소나 상황의 차이 또는 해석의 차이에 의해 서로 다른 결과를 생성하기도 한다. 따라서 현존하는 연구 결과들은 서로 상이한 정보를 제공할 수 있다. 유전자 정보의 통합을 통하여 이러한 불일치를 찾을 수 있다. 유전자 정보들이 불일치가 없이 통합 된다면 생물학자들은 어떤 유전자 정보를 알기 위해서 여러 연구 결과를 검토하지 않아도 되어 시간과 노력을 절감할 수 있게 된다. 이를 위하여 본 논문에서는 서로 다른 연구에 의해 구축된 유전자 정보를 하나의 정보로 통합 및 확장하는 기법을 소개한다.

Biologists are pursuing genetics related researches that can provide the core information to understand a certain cancer or inherent diseases. However, biological experimentations can produce different results by the difference of various elements or environments at the time of experimentation and/or difference of interpretations. Therefore, currently existing research results can possibly provide different information. These inconsistency can be found through integration of gene information. Biologists can save their time and efforts to find certain gene information if the gene information is integrated without inconsistency. An efficient gene integration and augmentation scheme of gene information generated through different researches is introduced in this paper.

키워드

참고문헌

  1. Bateman, A., Editorial. Nucleic Acids Research, Vol. 35,(Database Issue), D1-D2. 2007. https://doi.org/10.1093/nar/gkl1051
  2. McLeod, K. & A. Burger, Towards the use of argumentation in bioinformatics: a gene expression case study, Vol.24 ISMB i304-i312., 2008.
  3. ASPIC, Theoretical framework for argumentation, deliverable d2.1., 2004
  4. Dung, P.M., On the acceptability of argumentation and its fundamental role in nonmonotonic reasoning, logic programming and n-person games. Artificial Intelligence, Vol. 77, 321-358, 1995. https://doi.org/10.1016/0004-3702(94)00041-X
  5. McLeod, K., Gus Ferguson & A. Burger, Argudas: lessons for argumentation in biology based on a gene expression use case, BMC Bioinformatics, 13(Suppl 1):S8, 2012
  6. Davidson, D., The mouse atlas and graphical gene-expression database. Semin. Cell Dev. Biol. Vol. 8, 509-517., 1997. https://doi.org/10.1006/scdb.1997.0174
  7. Ringwald, M. et at., The mouse gene expression database (GXD), Nucleic Acids Research, Vol. 29, 98-101, 2001. https://doi.org/10.1093/nar/29.1.98
  8. Finger JH, Smith CM, Hayamizu TF, McCright IJ, Eppig JT, Kadin JA, Richardson JE, Ringwald M: The mouse Gene Expression Database (GXD): 2011 update. Nucleic Acids Res, 39(Database issue): D835-D841, 2011. https://doi.org/10.1093/nar/gkq1132
  9. http://www.emouseatlas.org/emap/home.html
  10. Terry F Hayamizu,Michael N Wicks, Duncan R Davidson, Albert Burger, Martin Ringwald and Richard A Baldock, EMAP/EMAPA ontology of mouse developmental anatomy, Journal of Biomedical Semantics. Vol.4., No.15, 2013,
  11. Lee, Y-J., The Effect of Information Conditions on Mental Health among Elderly, The Journal of Digital Policy & Management, v.11, no.10, 17-29, 2013.
  12. Han, D., M. Kang, Study on smart contents development directions for children with autistic disorder to enhance adaptive behavior, The Journal of Digital Policy & Management, v.11, no.10, 123-131, 2013.
  13. Sanghyuk Lee, Grouping DNA sequences with similarity measure and application, Journal of the Korea Convergence Society, v.4, no.3, 35-41, 2013. https://doi.org/10.15207/JKCS.2013.4.3.035
  14. Weon Kim, Min-Ho Kim, Gyu-Beom Shim, Moon-Ju Shin, A study on the satisfaction of Health Examination for National Health Insurance service -Target of medical examinee in Busan-, Journal of the Korea Convergence Society, v.4, no.2, 1-8, 2013. https://doi.org/10.15207/JKCS.2013.4.2.001
  15. Kyung-hee Kang, Moo-Sik Lee, Moon Sook Shim, Kwang-Hwan Kim, A Study on Awareness of Organization of Public Health Center based on Educational Background and Position, Journal of the Korea Convergence Society, v.2, no.1, 37-44, 2011.