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Reconstruction with fibular osteocutaneous free flap in patients with mandibular osteoradionecrosis

  • Kim, Min Gyun (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center) ;
  • Lee, Seung Tae (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center) ;
  • Park, Joo Yong (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center) ;
  • Choi, Sung Weon (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center)
  • Received : 2014.12.06
  • Accepted : 2015.01.13
  • Published : 2015.12.31

Abstract

Background: Osteoradionecrosis is a delayed complication from radiation therapy which causes chronic pain, infection and constant deformity after necrosis. Most of the osteoradionecrosis occurs spontaneously or after the primary oncologic surgery, dental extraction or by trauma of prosthesis. The treatment of osteoradionecrosis relies on both conservative measures and surgical measures. The fibular osteocutaneous free flap has become more popular choice for reconstruction of maxillofacial defects as a treatment of osteoradionecrosis. Methods: We presented our experiences from 7 patients with osteoradionecrosis who have had reconstruction surgery with fibular osteocutaneous free flap at National Cancer Center during the recent 5 years. We performed segmental mandibular resection with fibular osteocutaneous free flap for all 7 patients of advanced osteoradionecrosis who were not controlled by conservative treatment such as wound irrigation, debridement, and antibiotics. Results: A wide range of techniques were available for the reconstruction of composite defects resulted from the treatment of advanced mandibular osteoradionecrosis. Significant improvement was noted in relieving pain and treating trismus after the surgery however difficulty in swallowing and xerostomia showed less improvement. Conclusions: We concluded that fibular osteocutaneous free flap can be performed safely in patients with osteoradionecrosis and yields positive outcomes with significantly increased success rate. The fibular osteocutaneous free flap was our preferred choice for the mandibular reconstruction due to its versatility and predictability.

Keywords

References

  1. Ang E, Black C, Irish J, Brown DH, Gullane P, O'Sullivan B et al (2003) Reconstructive options in the treatment of osteoradionecrosis of the craniomaxillofacial skeleton. Br J Plast Surg 56:92-9 https://doi.org/10.1016/S0007-1226(03)00085-7
  2. Marx RE (1983) Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg 41:283-8 https://doi.org/10.1016/0278-2391(83)90294-X
  3. Marx RE, Johnson RP (1987) Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg Oral Med Oral Pathol 64:379-90 https://doi.org/10.1016/0030-4220(87)90136-8
  4. Marx RE, Johnson RP, Kline SN (1985) Prevention of osteoradionecrosis: a randomized prospective clinical trial of hyperbaric oxygen versus penicillin. J Am Dent Assoc 111:49-54 https://doi.org/10.14219/jada.archive.1985.0074
  5. Micha P, Imad Abu E-N, Yitzhak L, Leon A (2005) The use of free fibular flap for functional mandibular reconstruction. J Oral Maxillofac Surg 63:220-4 https://doi.org/10.1016/j.joms.2004.06.052
  6. Hirsch DL, Bell RB, Dierks EJ, Potter JK, Potter BE (2008) Analysis of microvascular free flaps for reconstruction of advanced mandibular osteoradionecrosis: a retrospective cohort study. J Oral Maxillofac Surg 66:2545-56 https://doi.org/10.1016/j.joms.2007.08.041
  7. Notani K, Yamazaki Y, Kitada H (2003) Management of mandibular osteoradionecrosis corresponding to the severity of osteoradionecrosis and the method of radiotherapy. Head Neck 25:181-6 https://doi.org/10.1002/hed.10171
  8. Happonen RP, Viander M, Pelliniemi L, Aitasalo K (1983) Actinomyces israelii in osteoradionecrosis of the jaws. Histopathologic and immunocytochemical study of five cases. Oral Surg Oral Med Oral Pathol 55(6):580-8 https://doi.org/10.1016/0030-4220(83)90374-2
  9. Rankow RM, Weissman B (1971) Osteoradionecrosis of the mandible. Ann Otol Rhinol Laryngol 80(4):603-11 https://doi.org/10.1177/000348947108000426
  10. Daly TE, Drane JB, MacComb WS (1972) Management of problems of the teeth and jaw in patients undergoing irradiation. Am J Surg 124(4):539-42 https://doi.org/10.1016/0002-9610(72)90082-7
  11. Annane D, Depondt J, Aubert P, Vilart M, Gehanno P, Gajdos P et al (2004) Hyperbaric oxygen therapy for radionecrosis of the jaw: A randomized, placebo-controlled, double blind trial from the OR96 study group. J Clin Oncol 22:4893-900 https://doi.org/10.1200/JCO.2004.09.006
  12. Etezadi A, Ferguson H, Emam HA, Walker P (2013) Multiple remediation of soft tissue reconstruction in osteoradionecrosis of the mandible: a case report. J Oral Maxillofac Surg 71:e1-6 https://doi.org/10.1016/S0278-2391(13)01290-1
  13. Park JH, Min KH, Eun SC (2004) Scalp free flap reconstruction using anterolateral thigh flap pedicle for interposition artery and vein grafts. Arch Plast Surg 39:55-8
  14. Wang L, Su Y-X, Liao G-Q (2009) Quality of life in osteoradionecrosis patients after mandible primary reconstruction with free fibula flap. Oral Surg Oral Med Oral Pathol Oral Radiol Endo 108:162-8 https://doi.org/10.1016/j.tripleo.2009.03.005
  15. Powell HR, Jaafar M, Bisase B, Kerawala CJ (2014) Resorption of fibula bone following mandibularreconstruction for osteoradionecrosis. Br J Oral Maxillofac Surg 52:375-8 https://doi.org/10.1016/j.bjoms.2014.02.005