Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
권호 표지
DOI QR코드

DOI QR Code

Clinical and radiographical evaluation of mineral trioxide aggregate, biodentine and propolis as pulpotomy medicaments in primary teeth

  • Kusum, Bharti (Department of Pedodontics and Preventive Dentistry, Maulana Azad Institute of Dental Sciences, MAMC complex) ;
  • Rakesh, Kumar (Department of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, King George Medical University) ;
  • Richa, Khanna (Department of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, King George Medical University)
  • Received : 2015.03.11
  • Accepted : 2015.07.22
  • Published : 2015.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA), Biodentine and Propolis as pulpotomy medicaments in primary dentition, both clinically and radiographically. Materials and Methods: A total of 75 healthy 3 to 10 yr old children each having at least one carious primary molar tooth were selected. Random assignment of the pulpotomy medicaments was done as follows: Group I, MTA; Group II, Biodentine; Group III, Propolis. All the pulpotomized teeth were evaluated at 3, 6, and 9 mon clinically and radiographically, based on the scoring criteria system. Results: The clinical success rates were found to be similar among the three groups at 3 and 6 mon where as a significant decrease in success rate was observed in Group III (84%) compared to both Group I (100%) and Group II (100%) at 9 mon. Radiographic success rates over a period of 9 mon in Groups I, II, and III were 92, 80, and 72%, respectively. Conclusions: Teeth treated with MTA and Biodentine showed more favorable clinical and radiographic success as compared to Propolis at 9 mon follow-up.

Keywords

References

  1. Caicedo R, Abbott PV, Alongi DJ, Alarcon MY. Clinical, radiographic and histological analysis of the effects of mineral trioxide aggregate used in direct pulp capping and pulpotomies of primary teeth. Aust Dent J 2006;51:297-305. https://doi.org/10.1111/j.1834-7819.2006.tb00447.x
  2. Magnusson B. Attempts to predict prognosis of pulpotomy in primary molars. Scand J Dent Res 1970;78:232-240.
  3. Ranly DM. Pulpotomy therapy in primary teeth: new modalities for old rationales. Pediatr Dent 1994;16:403-409.
  4. Eidelman E, Holan G, Fuks AB. Mineral trioxide aggregate vs. formocresol in pulpotomized primary molars: a preliminary report. Pediatr Dent 2001;23:15-18.
  5. Myers DR, Shoaf HK, Dirksen TR, Pashley DH, Whitford GM, Reynolds KE. Distribution of 14C-formaldehyde after pulpotomy with formocresol. J Am Dent Assoc 1978;96:805-813. https://doi.org/10.14219/jada.archive.1978.0187
  6. Primosch RE, Glomb TA, Jerrell RG. Primary tooth pulp therapy as taught in Predoctoral pediatric dental programs in the United States. Pediatr Dent 1997;19:118-122.
  7. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod 1999;25:197-205. https://doi.org/10.1016/S0099-2399(99)80142-3
  8. Holan G, Eidelman E, Fuks AB. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Pediatr Dent 2005;27:129-136.
  9. Oguntebi BR, Heaven T, Clark AE, Pink FE. Quantitative assessment of dentin bridge formation following pulpcapping in miniature swine. J Endod 1995;21:79-82. https://doi.org/10.1016/S0099-2399(06)81100-3
  10. Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc 1996;127:1491-1494. https://doi.org/10.14219/jada.archive.1996.0058
  11. Damamaschke T, Gerth HU, Zuchner H, Schafer E. Chemical and physical surface and bulk material characterization of white ProRoot MTA and two Portland cements. Dent Mater 2005;21:731-738. https://doi.org/10.1016/j.dental.2005.01.019
  12. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review-part I: chemical, physical, and antibacterial properties. J Endod 2010;36:16-27. https://doi.org/10.1016/j.joen.2009.09.006
  13. Laurent P, Camps J, About I. Biodentine induces TGF-${\beta}1$ release from human pulp cells and early dental pulp mineralization. Int Endod J 2012;45:439-448. https://doi.org/10.1111/j.1365-2591.2011.01995.x
  14. Peng W, Liu W, Zhai W, Jiang L, Li L, Chang J, Zhu Y. Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells. J Endod 2011;37:1240-1246. https://doi.org/10.1016/j.joen.2011.05.035
  15. Tran XV, Gorin C, Willing C, Baroukh B, Pellat B, Decup F, Opsahl Vital S, Chaussain C, Boukpessi T. Effect of a calicum-silicate-based restorative cement on pulp repair. J Dent Res 2012;91:1166-1171. https://doi.org/10.1177/0022034512460833
  16. Zanini M, Sautier JM, Berdal A, Simon S. Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and stimulates biomineralization. J Endod 2012;38:1220-1226. https://doi.org/10.1016/j.joen.2012.04.018
  17. Banskota AH, Tezuka Y, Kadota S. Recent progress in pharmacological research of propolis. Phytother Res 2001;15:561-571. https://doi.org/10.1002/ptr.1029
  18. Burdock GA. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 1998;36:347-363. https://doi.org/10.1016/S0278-6915(97)00145-2
  19. Marcucci MC. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 1995;26:83-99. https://doi.org/10.1051/apido:19950202
  20. Al-Haj Ali SN. In vitro toxicity of propolis in comparison with other primary teeth pulpotomy agents on human fibroblasts. J Investig Clin Dent 2015 Apr 27. doi:10.1111/jicd.12157. [Epub ahead of print]
  21. Ozorio JE, Carvalho LF, de Oliveira DA, de Sousa-Neto MD, Perez DE. Standardized propolis extract and calcium hydroxide as pulpotomy agents in primary pig teeth. J Dent Child(Chic) 2012;79:53-58.
  22. Parolia A, Kundabala M, Rao NN, Acharya SR, Agrawal P, Mohan M, Thomas M. A comparative histological analysis of human pulp following direct pulp capping with Propolis, mineral trioxide aggregate and Dycal. Aust Dent J 2010;55:59-64. https://doi.org/10.1111/j.1834-7819.2009.01179.x
  23. Zurn D, Seale NS. Light-cured calcium hydroxide vs formocresol in human primary molar pulpotomies: a randomized controlled trial. Pediatr Dent 2008;30:34-41.
  24. Sushynski JM, Zealand CM, Botero TM, Boynton JR, Majewski RF, Shelburne CE, Hu JC. Comparison of gray mineral trioxide aggregate and diluted formocresol in pulpotomized primary molars: a 6- to 24-month observation. Pediatr Dent 2012;34:120-128.
  25. Scheller S, Ilewicz L, Luciak M, Skrobidurska D, Stojko A, Matuga W. Biological properties and chemical application of propolis. IX. Experimental observation on the influence of ethanol extract of propolis (EEP) on dental pulp regeneration. Arzeimittelforschung 1978;28:289-291.
  26. Nowicka A, Lipski M, Parafiniuk M, Sporniak-Tutak K, Lichota D, Kosierkiewicz A, Kaczmarek W, Buczkowska-Radlinska J. Response of human dental pulp capped with biodentine and mineral trioxide aggregate. J Endod 2013;39:743-747. https://doi.org/10.1016/j.joen.2013.01.005
  27. Park YK, Alencar SM, Aguiar CL. Botanical origin and chemical composition of Brazilian propolis. J Agric Food Chem 2002;50:2502-2506. https://doi.org/10.1021/jf011432b
  28. Croll TP, Killian CM. Zinc oxide-eugenol pulpotomy and stainless steel crown restoration of a primary molar. Quintessence Int 1992;23:383-388.
  29. Gruythuysen RJ, Weerheijm KL. Calcium hydroxide pulpotomy with a light-cured cavity-sealing material after two years. ASDC J Dent Child 1997;64:251-253.
  30. Zealand CM, Briskie DM, Botero TM, Boynton JR, Hu JC. Comparing gray mineral trioxide aggregate and diluted formocresol in pulpotomized human primary molars. Pediatr Dent 2010;32:393-399.
  31. Erdem AP, Guven Y, Balli B, Ilhan B, Sepet E, Ulukapi I, Aktoren O. Success rates of mineral trioxide aggregate, ferric sulfate, and formocresol pulpotomies: a 24-month study. Pediatr Dent 2011;33:165-170.
  32. Willard RM. Radiographic changes following formocresol pulpotomy in primary molars. ASDC J Dent Child 1976;43:414-415.
  33. Fuks AB, Holan G, Davis JM, Eidelman E. Ferric sulfate versus dilute formocresol in pulpotomized primary molars: long-term follow up. Pediatr Dent 1997;19:327-330.
  34. Koo H, Gomes BP, Rosalen PL, Ambrosano GM, Park YK, Cury JA. In vitro antimicrobial activity of propolis and arnica montana against oral pathogens. Arch Oral Biol 2000;45:141-148. https://doi.org/10.1016/S0003-9969(99)00117-X
  35. Silva FB, Almeida JM, Sousa SM. Natural medicaments in endodontics - a comparative study of the antiinflammatory action. Bra Oral Res 2004;18:174-179. https://doi.org/10.1590/S1806-83242004000200015
  36. Tan-No K, Nakajima T, Shoji T, Nakagawasai O, Niijima F, Ishikawa M, Endo Y, Sato T, Satoh S, Tadano T. Antiinflammatory effect of propolis through inhibition of nitric oxide production on carrageenin-induced mouse paw edema. Biol Pharm Bull 2006;29:96-99. https://doi.org/10.1248/bpb.29.96
  37. Jabbarifar SE, Khademi AA, Ghasemi D. Success rate of formocresol pulpotomy versus mineral trioxide aggregate in human primary molar tooth. J Res Med Sci 2004;9:304-307.
  38. Sonmez D, Sari S, Cetinbas T. A Comparison of four pulpotomy techniques in primary molars: a long-term follow-up. J Endod 2008;34:950-955. https://doi.org/10.1016/j.joen.2008.05.009
  39. del Carmen Gonzalez Rodriguez W, Carpio MHC, Ramos MRM, Milanes MG, Antunez LN. Pulpotomies of dead pulps in temporal molars using 10% propolis tinction. Rev Cubana Estomatol [online] 2007;44(3). Available from: http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75072007000300006&lng=en&nrm=iso&tlng=en (updated 2015 Sep 3).
  40. Waterhouse PJ, Nunn JH, Whitworth JM. Primary molar vital pulp theory. Br Dent J 2000;188:417.

Cited by

  1. Clinical and radiographic comparison of biodentine, mineral trioxide aggregate and formocresol as pulpotomy agents in primary molars vol.18, pp.4, 2017, https://doi.org/10.1007/s40368-017-0299-3
  2. Success Rates of Pulpotomies in Primary Molars Using Calcium Silicate-Based Materials: A Randomized Control Trial vol.2017, pp.2314-6141, 2017, https://doi.org/10.1155/2017/4059703
  3. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part I: vital pulp therapy pp.01432885, 2018, https://doi.org/10.1111/iej.12841
  4. Biodentine™ material characteristics and clinical applications: a 3 year literature review and update vol.19, pp.1, 2018, https://doi.org/10.1007/s40368-018-0328-x
  5. Microleakage and Shear Bond Strength of Biodentine at Different Setting Time vol.45, pp.3, 2018, https://doi.org/10.5933/JKAPD.2018.45.3.344
  6. How does the pulpal response to Biodentine and ProRoot mineral trioxide aggregate compare in the laboratory and clinic? vol.225, pp.8, 2018, https://doi.org/10.1038/sj.bdj.2018.864
  7. MTA and biodentine for primary teeth pulpotomy: a systematic review and meta-analysis of clinical trials pp.1436-3771, 2019, https://doi.org/10.1007/s00784-018-2616-6
  8. Recent Trends in Tricalcium Silicates for Vital Pulp Therapy vol.5, pp.3, 2018, https://doi.org/10.1007/s40496-018-0186-y
  9. Clinical and radiographic evaluation of biodentine versus calcium hydroxide in primary teeth pulpotomies: a retrospective study vol.18, pp.1, 2018, https://doi.org/10.1186/s12903-018-0522-6
  10. The evaluation of MTA and Biodentine as a pulpotomy materials for carious exposures in primary teeth pp.1436-3771, 2018, https://doi.org/10.1007/s00784-018-2472-4
  11. BiodentineTM versus formocresol pulpotomy technique in primary molars: a 12–month randomized controlled clinical trial vol.19, pp.1, 2019, https://doi.org/10.1186/s12903-018-0702-4
  12. Biodentine: from biochemical and bioactive properties to clinical applications vol.30, pp.2, 2016, https://doi.org/10.1016/j.gien.2016.09.002
  13. Randomized Controlled Trial of Pulpotomy in Primary Molars using MTA and Formocresol Compared to 3Mixtatin: A Novel Biomaterial vol.42, pp.5, 2018, https://doi.org/10.17796/1053-4625-42.5.7
  14. Clinical and Radiographic Evaluations of Biodentine™ Pulpotomies in Mature Primary Molars (Stage 2) vol.11, pp.6, 2015, https://doi.org/10.5005/jp-journals-10005-1564
  15. Comparative Evaluation of Success of Biodentine and Mineral Trioxide Aggregate with Formocresol as Pulpotomy Medicaments in Primary Molars: An In Vivo Study vol.13, pp.2, 2015, https://doi.org/10.5005/jp-journals-10005-1740
  16. Clinical and Radiographic Evaluation of Pulpotomy using MTA, Biodentine and Er,Cr : YSGG Laser in primary teeth- A Clinical Study vol.29, pp.1, 2015, https://doi.org/10.5978/islsm.20-or-03
  17. A Comparative Evaluation between Propolis and Mineral Trioxide Aggregate as Pulpotomy Medicaments in Primary Molars vol.9, pp.15, 2020, https://doi.org/10.14260/jemds/2020/273
  18. 치수복조재와 최종수복재에 따른 대구치 부분치수절단술의 비교 vol.47, pp.2, 2015, https://doi.org/10.5933/jkapd.2020.47.2.148
  19. The use of propolis in dentistry, oral health, and medicine: A review vol.63, pp.1, 2015, https://doi.org/10.1016/j.job.2021.01.001