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Effects of Chunggukjang and Greentea-Chunggukjang on Lipid Profile and Antioxidative Enzyme Activity of Liver Tissue in Growing Rats Fed Cholesterol

청국장과 녹차청국장이 고콜레스테롤 식이를 섭취한 성장기 쥐의 Lipid Profile 및 항산화효소 활성에 미치는 영향

  • Jung, Yun-Jung (Dept. of Food and Nutrition, Keimyung University) ;
  • Choi, Mi-Ja (Dept. of Food and Nutrition, Keimyung University)
  • 정윤정 (계명대학교 식품영양학과) ;
  • 최미자 (계명대학교 식품영양학과)
  • Received : 2015.03.09
  • Accepted : 2015.04.15
  • Published : 2015.04.30

Abstract

The overall purpose of this study was to investigate the effects of Chunggukjang and Greentea-Chunggukjang on the lipid profile, lipid peroxidation and antioxidative enzyme activities of liver tissue in growing male rats fed cholesterol. Twenty seven rats were divided into three treatment groups (Control, Chunggukjang and Greentea-Chunggukjang) and were given experimental diets with 1% cholesterol for 9 weeks. All rats in this study were fed a casein-based diet. Chunggukjang groups were fed diet containing 33.1% Chunggukjang powder. The Chunggukjang and Greentea-Chunggukjang groups showed significantly lower weight gain, food efficiency ratio than the control group regardless of Chunggukjang type. Serum total cholesterol was significantly lower in the Chunggukjang group than in the control group, whereas serum triglyceride and atherogenic index were significantly lower in the Greentea-Chunggukjang group than in the control group. Hepatic triglyceride contents was not significantly different among the diets. However, hepatic cholesterol content was significantly lower in the Greentea-Chunggukjang group than in the control group. Lipid peroxidation of malondialdehyde (MDA) contents was significantly lower in the Chunggukjang and Greentea-Chunggukjang groups than in the control group. Activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) in liver tissue of the Chunggukjang and Greentea-Chunggukjang groups were not significantly different. It can be concluded that Chunggukjang and Greentea-Chunggukjang influence lipid profile and hepatic malondialdehyde contents in growing male rats fed cholesterol.

Keywords

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