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The Effects of Menopause on the Metabolic Syndrome in Korean Women

폐경이 대사증후군에 미치는 영향

  • Bang, SoYoun (Division of Nursing, Daejeon Institute of Science and Technology) ;
  • Cho, IlGu (Technology Planning Division, Institute for Information & communications Technology Promotion)
  • 방소연 (대전과학기술대학교 간호학부) ;
  • 조일구 (정보통신기술진흥센터 기술기획그룹)
  • Received : 2014.11.21
  • Accepted : 2015.04.09
  • Published : 2015.04.30

Abstract

This study was the secondary analysis using the Korea National Health and Nutrition Examination Survey of 2012 and purpose was to investigate the effects of menopause on the metabolic syndrome(MetS) in Korean women. In raw data, total 2,746 women aged ${\geq}19$ years and provided the correct data about menstruation and menopause were analysed. The results were as follows: First, components of MetS were significantly different according to menopausal status. Second, the prevalence of MetS was 13.2% in premenopausal women and 42.7% in postmenopausal women. Third, the Odds ratio of postmenopausal women was 4.88(95% CI=3.888-6.126) compared with premenopausal women for MetS. As 5 years from 40 years increased, the Odds ratios of postmenopausal women were 3.15(95% Confidence Interval=1.862-5.331), 4.159(2.558-6.761), 5.971(3.955-9.016), 9.52(6.591-13.749) compared with premenopausal women for MetS, respectively. Based on the results, the intervention should be developed and provided for preventing and managing the MetS in postmenopausal women.

본 연구는 국민건강영양조사 2012년도 원시자료를 이용한 이차분석 연구로서, 연구 목적은 폐경이 대사증후군 유병율 및 구성요소에 미치는 영향을 확인하는 것이다. 층화집락복합표본추출로 선정된 총 8,058명 중 만 19세 이상 성인 여성이며 월경 및 폐경에 대한 정확한 정보를 제공한 2,746명을 대상으로 하였다. 연구결과, 폐경 여부에 따른 대사증후군 구성요소의 평균 차이는 모두 통계적으로 유의하였다. 대사증후군 유병율은 폐경 전 여성 13.2%, 폐경 후 여성 42.7%이었다. 폐경후 대사증후군에 이환될 확률은 4.88배(95% CI=3.888-6.126) 증가하고, 40세를 기준으로 나이가 5세 증가할 때마다 대사증후군에 이환될 확률은 각각 3.15배(95% CI=1.862-5.331), 4.159배(2.558-6.761), 5.971배(3.955-9.016), 9.52배(6.591-13.749) 증가하였다. 연구 결과를 바탕으로 폐경 후 여성의 대사증후군 예방 및 관리를 위한 중재 프로그램이 개발 및 적용되어야 할 것이다.

Keywords

References

  1. E. S. Ford, W. H. Giles, W. H. Dietz, "Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey", JAMA, Vol.287, pp.256-259, 2002. DOI: http://dx.doi.org/10.1001/jama.287.3.356
  2. S. M. Grundy, J. I. Cleeman, S. R. Daniels, et al., "Diagnosis and management of the metabolic syndrome: an American Heart Association/ National heart, Lung, and Blood Institute scientific statement", Circulation, Vol.112, No.17, pp.2735- 2752, 2005. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.105.169405
  3. M. J. Kim, E. Park, "The prevalence and the related factors of metabolic syndrome in Urban and rural community", Korean Journal of Adult Nursing, Vol.26, No.1, pp.67-77, 2014. DOI: http://dx.doi.org/10.7475/kjan.2014.26.1.67
  4. H. M. Kang, D. J. Kim, "Metabolic syndrome versus Framingham Risk Score for association of self-reported coronary heart disease: the 2005 Korean Health and Nutrition Examination Survey", Diabetes & Metabolism Journal, Vol.36, pp.237-244, 2012. DOI: http://dx.doi.org/10.4093/dmj.2012.36.3.237
  5. K. G. Alberti, R. H. Eckel, S. M. Grundy, P. Z. Zimmet, J. I. Cleeman, K. A. Donato, et al., "Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity", Circulation, Vol.120, No.16, pp.1640-1645, 2009. DOI: http://dx.doi.org/10.1161/CIRCULATIONAHA.109.192644
  6. N. Sarrafzadegan, M. Gharipour, M. A. Ramezani, K. Rabiei, B. Zolfaghar, A. A. Tavassoli, et al., "Metabolic syndrome and health-related quality of life in Iranian population", Journal of Research in Medical Science, Vol.16, No.3, pp.254-261, 2011.
  7. S. Lim, H. Shin, J. H. Song, S. H. Kwak, S. M. Kang, J. W. Yoon, et al., "Increasing prevalence of metabolic syndrome in Korea: the Korean National Health and Nutrition Examination Survey for 1998-2007", Diabetes Care, Vol.34, No.6, pp.1323-1328, 2011. DOI: http://dx.doi.org/10.2337/dc10-2109
  8. E. O. Park, S. J, Choi, H, Y, Lee, "The prevalence of metabolic syndrome and related risk factors based on the KNHANES V 2010", Journal of Agricultural Medicine and Community Health, Vol.38, No.1, pp.1-13, 2013. DOI: http://dx.doi.org/10.5393/JAMCH.2013.38.1.001
  9. E. G. Oh, S. Y. Bang, S. S. Hyun, S. H. Chu, J. Y. Jeon, M S, Kang, "Knowledge, perception and health bahavior about metabolic syndrome for an at risk group in a rural community area", Journal of Korean Academy of Nursing, Vol.37, No.5, pp.790-800, 2007 https://doi.org/10.4040/jkan.2007.37.5.790
  10. M. Y. Im, Y. R. Lee, S. J. Han, C. M. Cho, "The effects of lifestyle factors on metabolic syndrome among Korean adults", Journal of Korean Academy of Community Health Nursing, Vol.23, No.1, pp.13-21, 2012. DOI: http://dx.doi.org/10.12799/jkachn.2012.23.1.13
  11. Y. Lee, S. Y. Woo, J. H. Ahn, S. Cho, S. R. Kim, "Health-related quality of life in adults with metabolic syndrome: the Korean National Health and Nutrition Examination Survey, 2007-2008", Annals of Nutrition & Metabolism, Vol.61, pp.275-280, 2012. DOI: http://dx.doi.org/10.1159/000341494
  12. S. G. Wannamethee, A. G. Shaper, P. H. Whincup, "Modifiable lifestyle factors and metabolic syndrome in older men: effects on lifestyle changes", Journal of the American Geriatrics Society, Vol.54, pp.1909-1914, 2006. DOI: http://dx.doi.org/10.1111/j.1532-5415.2006.00974.x
  13. J. K. Joo, J. B. Son, J. E. Jung, S. C. Kim, K. S. Lee, "Differences of prevalence and components of metabolic syndrome according to menopausal status", Journal of Korean Society of Menopause, Vol.18, No.3, pp.155-162, 2012. DOI: http://dx.doi.org/10.6118/jksm.2012.18.3.155
  14. M. S. Han, "Metabolic syndrome emerging from menopause", Journal of Korean Society of Menopause, Vol.17, No.3, pp.127-135, 2011. DOI: http://dx.doi.org/10.6118/jksm.2011.17.3.127
  15. C. P. Spencer, I. F. Godsland, J. C. Stevenson, "Is there a menopausal metabolic syndrome?", Gynecological Endocrinology, Vol.11, No.5, pp.341-355, 1997. DOI: http://dx.doi.org/10.3109/09513599709152559
  16. H. M. Kim, J. Park, S. Y. Ryu, J. Kim, "The effects of menopause on the metabolic syndrome among Korean Women: the Korean National Health and Nutrition Examination Survey", Diabetes Care, Vol.30, pp.701-706, 2007. DOI: http://dx.doi.org/10.2337/dc06-1400
  17. M. H. Kim, M. K. Kim, B. Y. Choi, Y. J. Shin, "Prevalence of the metabolic syndrome and its association with cardiovascular diseases in Korea", Journal of Korean Medical Science, Vol.19, No.2, pp.195-201, 2004. DOI: http://dx.doi.org/10.3346/jkms.2004.19.2.195
  18. N. J. A. Figueiredo, E. D. Figueredo, J. B. Barbosa, F. F. Barbosa, G. R. Costa, V. J. Nina, et al., "Metabolic syndrome and menopause: cross-sectional study in gynecology clinic", Arquivos Brasileiros de Cardiologia, Vol.95, No.3, pp.339-345, 2010. https://doi.org/10.1590/S0066-782X2010005000094
  19. I. Janssen, L. H. Powell, S. Crawford, B. Lasley, K. Sutton-Tyrrell, "Menopause and the metabolic syndrome: the Study of Women's Health Across the Nation", Archives of Internal Medicine, Vol.168, No.14, pp.1568-1575, 2008. DOI: http://dx.doi.org/10.1001/archinte.168.14.1568
  20. Korea Centers for Disease Control and Prevention, The fifth Korea National Health and Nutrition Examination Suevey(KNHANES V-3), 2012.
  21. Who Expert Consultation, "Appropriate body mass index for Asian population and its implications for policy and intervention strategies", Lancet, Vol. 44, pp. 157-163.
  22. S. Ben Ali, H. Belfki-Benali, H. Aounallah- Skhiri, P. Traissac, B. Maire, F. Delpeuch, et al., "Menopause and metabolic syndrome in Tunisian women", BioMed Research International, Epub print of ahead 2014 Mar 31.
  23. S. Pandey, M. Srinivas, S. Agashe, J. Joshi, P. Galvankar, C. P. Prakasam, et al., "Menopause and metabolic syndrome: A study of 498 urban women from western India", Journal of Midwife Health, Vol.1, No.2, pp.63-69, 2010.
  24. S. Goyal, M. Baruah, R. Devi, K. Jain, "Study on relation of metabolic syndrome with menopause", Indian Journal of Clinical Biochemistry, Vol.28, No.1, pp.55-60, 2013. DOI: http://dx.doi.org/10.1007/s12291-012-0243-6
  25. C. M. Ferrara, N. A. Lynch, B. J. Nicklas, A. S. Ryan, D. M. Berman, D. M. "Differences of adipose tissue metabolism between postmenopausal and perimanopausal women", The Journal of Clinical Endocrinology and Metabolism, Vol.87, pp.4166-4170, 2002. DOI: http://dx.doi.org/10.1210/jc.2001-012034
  26. S. L. Crawford, V. A. Casey, N. E. Avis, S. M. McKinlay, S. M. "A longitudinal study of weight the menopause transition: results from the Massachusetts Women's Health Survey", Menopause, Vol.7, pp.96-104, 2000. DOI: http://dx.doi.org/10.1097/00042192-200007020-00005
  27. D. Grady, D., Herrington, N. Bittner, R. Blumenthal, M. Davidson, M. Hlatky, et al., "Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up(HERS II)", JAMA, Vol.288, pp.49-57, 2002. https://doi.org/10.1001/jama.288.1.49
  28. J. E. Manson, J. Hsia, K. C. Johnson, J. E. Rossouw, A. R. Assaf, N. L. Lasser, et al., "Estrogen plus progestin and the risk of coronary heart disease", New England Journal of Medicine, Vol.349, pp.523-534, 2003. DOI: http://dx.doi.org/10.1056/NEJMoa030808
  29. M. C. Pouliot, J. P. Despres, A. Nadeau, S. Moorjani, D. Prus'Homme, P. J. Lupien, et al., "Visceral obesity in men. Association with glucose tolerance, plasma insulin, and lipoprotein levels", Diabetes, Vol.41, pp.826-834, 1992. DOI: http://dx.doi.org/10.2337/diab.41.7.826
  30. H. S. Shim. H. S. Kim, J. H. Kim, "Analysis of metabolic syndrome risk factors among the menopausal women in her fifties:, Journal of Korean Biological Nirsing Science, Vol.12, Np.1, pp.58-62, 2010.

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