Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of Photodynamics Therapy on the Acne Skin without Light Sensitive Material

광민감물질이 배제된 광선역학요법이 여드름 피부에 미치는 효과

  • 박선남 (호서대학교 한방화장품학과) ;
  • 김경연 (신성대학교 미용예술계열)
  • Received : 2015.01.19
  • Accepted : 2015.05.07
  • Published : 2015.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

At a dermatology during the skin care, photodynamic therapy(PDT) is carried after 5-aminolevulinic acid(ALA), light sensitive material, is applied. At a skin care shop, using drug is prohibited. Thus, the aim of this research was to see the effect of the acne skin by irradiating PDT to the skin without applying ALA. The research method was that 24 female undergraduates who had acne on their face at the level of mild or comedonal, and the participants were divided into four groups(group1: no treatment, group 2: 420 nm of blue visible light, group 3: 660 nm of red visible light and group 4: blue and red visible light). The participants of group 2, 3 and 4 were irradiated with visible light for 20 minutes per week for 6 weeks, and they were compared to group 1. As a result of the research, the number of erythema, sebum, papules and pustules of those who were irradiated with visible light decreased, and the pore size of those also decreased while the amount of moisture increased. If an skin care shop applies PDT to the existing acne skin care, that PDT will influence on the program of a skin care shop is expected.

피부과에서는 여드름 피부관리 시 광민감물질인 5-aminolevulinic acid(ALA)를 도포한 후 광선역학요법(Photodynamic therapy, PDT)을 실시한다. 피부관리실에서는 의약품 사용은 금지되어 있다. 따라서 이 연구의 목적은 의약품인 ALA를 도포하지 않고 광선역학요법을 여드름 피부관리 프로그램에 도입하여 그 효과를 알아보았다. 연구 방법은 면포 및 경도 여드름을 가진 여대생 24명을 네 그룹(1군: 대조군, 2군: 420 nm 파장의 청색광 조사, 3군: 660 nm 의 적색광 조사, 4군: 청색광과 적색광을 조사)으로 나누어 2, 3, 4군을 6주간 주 1회 가시광선을 20분씩 조사한 후, 대조군과 비교하였다. 그 결과 가시광선이 조사된 그룹은 홍반, 유분량, 구진, 농포의 수가 감소하였고, 모공의 크기가 축소되었으며 수분량은 증가하였다. 피부관리실의 현재 여드름관리와 광선역학요법을 병행한다면 피부관리실의 여드름 프로그램에 긍정적인 효과를 줄 것이라 기대된다.

Keywords

References

  1. Haekyung Lee. Effects of Sociocultural Attitude toward Appearance, Body Image, and Self-Esteem on Appearance Management in Middle and High School Girls. Journal of the Korea Academia-Industrial cooperation Society, 15(2) 914-922, 2014. DOI: http://dx.doi.org/10.5762/KAIS.2014.15.2.914
  2. Haekyung Lee. Predictors of Wish to Undergo Cosmetic Surgery according to Experience of Cosmetic Surgery in Female College Students. Journal of the Korea Academia-Industrial cooperation Society, 14(1) 285-293, 2013. DOI: http://dx.doi.org/10.5762/KAIS.2013.14.1.285
  3. Cordain L, Lindeberg S, Hurtado M, Hill K, Eaton SB, Brand-Miller J. Acne vulgaris : A disease of wester civilization. Arch Dermatol., 138(12) 1584-1590, 2002. DOI: http://dx.doi.org/10.1001/archderm.138.12.1584
  4. Jungeun Lee. A study on Facial Acne management by LED of visible ray wavelength : Focusing on the twenties. Chungand University Master Thesis, 2007.
  5. Webster GF, Grabger EM. Antibiotic treatment for acne vulgaris. Semin. Cutan. Med. Surg., 27(3) 183-187, 2008. DOI: http://dx.doi.org/10.1016/j.sder.2008.07.001
  6. Eady EA, Gloor M and Leyden JJ. Propionibacterium acnes resistance: A World Wide Problem, Dermatol., 206(1) 54-6, 2003. DOI: http://dx.doi.org/10.1159/000067822
  7. EunJin Jung. study on the medical esthetic conditioning,customer satisfaction and reformation plan. Chungand University Master Thesis, 2007.
  8. Cunliffe WJ, Goulden V. Phototherapy and acne vulgaris. Br J Dermatol, 142(5) 855-856, 2000. DOI: http://dx.doi.org/10.1046/j.1365-2133.2000.03528.x
  9. Sigurdsson V, Knulst AC, Van Weelden H. Phototheropy of acne vulgaris with visible light. Dermatology, 194(3) 256-260, 1997. DOI: http://dx.doi.org/10.1159/000246114
  10. Mariwallas K, Rohrer TE. Use of lasers and light-based therapies for treatment of acne vulgaris. Lasers Surg Med, 37(5) 333-342, 2005. DOI: http://dx.doi.org/10.1002/lsm.20276
  11. Goldberg DJ, Russell BA. Combination blue(415nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris. J Cosment Laser ther, 8(2) 71-75, 2006. DOI: http://dx.doi.org/10.1080/14764170600735912
  12. Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J Photochem Photobiol B, 6(1) 143-148, 1990. https://doi.org/10.1016/1011-1344(90)85083-9
  13. HyunSook Jung. The effect of permeation of vitamin C iontophoresis on the improvement of acne and acne scar after medical treatment. Konkuk University Master Thesis, 2006.
  14. Jeong-Suk Lee, Kyung-Min Ahn. Korean Skin Care on Japanese Tourist's Satisfaction and Revisit. Journal of the Korea Academia-Industrial Cooperation Society, 12(11) 4756-4763, 2011. DOI: http://dx.doi.org/10.5762/KAIS.2011.12.11.4756
  15. Elman M. Lebzelter J. Light therapy in the treatment of acne vulgaris. Dermatol Surg. 30(2) 139-146, 2004. DOI: http://dx.doi.org/10.1111/j.1524-4725.2004.30053.x
  16. Seonnam Park. Treatment Effects of MTS and Iontophoresis on the Improvement of Skin Status in Twenties' Female College Students. KSIC, 9(3) 213-219, 2013.
  17. Rogiers V. EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences. Skin Pharmacol Appl Skin Physiol, 14(1) 117-128, 2001. DOI: http://dx.doi.org/10.1159/000056341
  18. Aimbire F, Albertini R, Pacheco MT, Castro-Faria-Neto HC, Leonardo PS, Iversen VV et al,. Low-level laser therapy induces does-dependent reduction of TNF alpha levels in acute inflammation. Photomed Laser Surg., 24(1) 33-37, 2006. DOI: http://dx.doi.org/10.1089/pho.2006.24.33
  19. BH Lee, HO Kim , HJ Han , KS Kang , CW Park , CH Lee. Phtotherapy of acne vulgaris with low level narrow band red light (680 nm). Korean J Dermatol, 42(12) 1566-1573, 2004.
  20. Na JI, Suh DH. Red light phototherapy alone is effective for acne vulgaris: randomized, single-blinded clinical trial. Dermatol Surg, 33(10) 1228-1233, 2007. DOI: http://dx.doi.org/10.1111/j.1524-4725.2007.33258.x
  21. Hongcharu W, Taylor CR, Chang Y, Aghassi D, Suthamjariya K, Anderson RR. Topical ALAphotodynamic therapy for the treatment of acne vulgaris. J invest Dermatol, 115(2) 183-192, 2000. DOI: http://dx.doi.org/10.1046/j.1523-1747.2000.00046.x
  22. Jeon HJ, Kin SH, Hahm JH, Whang KK. A comparison of ALA-IPL photodynamic therapy and acne mode IPL phototherapy in the treatment of acne vulgaris. Korean J Dermatol, 45(1) 14-22, 2007.
  23. Medrado AR, Pugliese LS, Reis SR, Andrade ZA. Influence of low level laser therapy on wound healing and its biological action upon myofibrobiasts. Lasers Surg Med, 32(3) 239-244, 2003. DOI: http://dx.doi.org/10.1002/lsm.10126
  24. Young S, Boltron P, Dyson M, Harvey W, Diamantopoulos C. Macrophage responsiveness to light therapy. Lasers Surg Med, 9(5) 497-505, 1989. DOI: http://dx.doi.org/10.1002/lsm.1900090513
  25. Corazza AV, Jorge J, Kurachi C, Bagnato VS. Photobiomodulation on the angiogenesis of skin wounds in rats using different light sources. Photomed Laser Surg, 25(2) 102-106, 2007. DOI: http://dx.doi.org/10.1089/pho.2006.2011
  26. Gold MH. Acne and PDT: new techniques with lasers and Light sources. Lasers Med Sci, 22(2) 67-72, 2007. DOI: http://dx.doi.org/10.1007/s10103-006-0420-z
  27. Takahashi H, Itoh Y, Miyauchi Y, Nakajima S, Sakata I, Ishida-Yamamoto A, et al. Activation of two caspase cascades, caspase 8/3/8 and caspase 9/3/6, during photodynamic therapy using a novel photosensitizer, ATX-S10 (Na), in normal human keratinocytes. Arch Dermatol Res, 295(6) 242-248, 2003. DOI: http://dx.doi.org/10.1007/s00403-003-0424-5