Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지
DOI QR코드

DOI QR Code

Congenital systemic melanosis in a black mongrel pig

흑돼지에서의 선천성 전신 멜라닌증 발생 증례

  • Jeong, Yea-Ji (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Jung, Ji-Youl (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Her, Ji-Woong (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Baek, Kang-Hyun (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Lee, Jong-Hyeong (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Lee, Myoung-Heon (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency) ;
  • Yoon, Soon-Seek (Division of Animal Disease Diagnosis, Department of Animal Disease Control and Quarantine, Animal and Plant Quarantine Agency)
  • 정예지 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 정지열 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 허지웅 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 백강현 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이종형 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 이명헌 (농림축산검역본부 동물질병관리부 질병진단과) ;
  • 윤순식 (농림축산검역본부 동물질병관리부 질병진단과)
  • Received : 2015.01.09
  • Accepted : 2015.05.11
  • Published : 2015.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Four 3-day-old piglets with retarded growth were submitted to the Animal and Plant Quarantine Agency for diagnosis. Necropsy showed that one piglet had black spots ranging from 2 mm to 1 cm in diameter in the cerebellum, lungs, regional lymph nodes, and cecum. Histological findings were consistent with the gross appearance in which melanin pigmentation was observed in the organs mentioned above. Based on Fontana-Masson staining, we diagnosed this animal with systemic melanosis. To the best of our knowledge, this is the first case of systemic melanosis in black breeds of swine in Korea.

Keywords

References

  1. Bundza A, Feltmate TE. Melanocytic cutaneous lesions and melanotic regional lymph nodes in slaughter swine. Can J Vet Res 1990, 54, 301-304.
  2. Bohm M, Schiller M, Nashan D, Stadler R, Luger TA, Metze D. Diffuse melanosis arising from metastatic melanoma: pathogenetic function of elevated melanocyte peptide growth factors. J Am Acad Dermatol 2001, 44, 747-754. https://doi.org/10.1067/mjd.2001.112349
  3. Caylor HD, Schlotthauer CF. Melano-epitheliomas of swine: transplantation and cultural experiments. Arch Pathol Lab Med 1926, 2, 343-351.
  4. Davis CL, Leeper RB, Shelton JE. Neoplasms encountered in federally inspected establishments in Denver, Colorado. J Am Vet Med Assoc 1933, 83, 229-237.
  5. Grossi AB, Hyttel P, Jensen HE, Leifsson PS. Porcine melanotic cutaneous lesions and lymph nodes: immunohistochemical differentiation of melanocytes and melanophages. Vet Pathol 2014, 52, 83-91.
  6. Jin B, Zaidi SY, Hollowell M, Hollowell C, Saleh H. A unique case of urinary bladder simple melanosis: a case report and review of the literature. Diagn Pathol 2009, 4, 24. https://doi.org/10.1186/1746-1596-4-24
  7. Kim SY, Choung RS, Kwon BS, Hyun JJ, Jung SW, Koo JS, Yim Hj, Lee SW, Choi JH. Small bowel pseudomelanosis associated with oral iron therapy. J Korean Med Sci 2013, 28, 1103-1106. https://doi.org/10.3346/jkms.2013.28.7.1103
  8. Klaus MV, Shah F. Generalized melanosis caused by melanoma of the rectum. J Am Acad Dermatol 1996, 35, 295-297. https://doi.org/10.1016/S0190-9622(96)90652-0
  9. Klein-Szanto A, Bradl M, Porter S, Mintz B. Melanosis and associated tumors in transgenic mice. Proc Natl Acad Sci U S A 1991, 88, 169-173. https://doi.org/10.1073/pnas.88.1.169
  10. Myers R, McGavin MD. Endogenous pigments. In: McGavin MG, Zachary JF (eds.). Pathologic Basis of Veterinary Disease. 4th ed. pp. 51-53, Mosby, St. Louis, 2007.
  11. Sebaratnam DF, Venugopal SS, Frew JW, McMillan JR, Finkelstein ER, Martin LK, Murrell DF. Diffuse melanosis cutis: a systematic review of the literature. J Am Acad Dermatol 2013, 68, 482-488. https://doi.org/10.1016/j.jaad.2012.08.018
  12. Stalker M, Hayes M. Pigmentation. In: Maxie MG (ed.). Jubb, Kennedy, And Palmer' Pathology of Domestic Animals. 5th ed. pp. 307-308, Saunders, Edinburgh, 2007