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The effects of labeling gap and susceptibility artifacts in pCASL perfusion MRI

pCASL 관류 영상에서 표지 간격과 자화감수성 인공물이 영상에 미치는 영향

  • Kim, Seong-Hu (Department of radiology, Gyeongsang National Univ. Hospital)
  • 김성후 (경상대학교병원 영상의학과)
  • Received : 2015.04.28
  • Accepted : 2015.06.25
  • Published : 2015.06.30

Abstract

To report problems found in a patient who has implemented stent implantation and then conducted a perfusion MRI using ASL(Arterial Spin Labeling), in order to suggest a solution to them. The perfusion MRI was conducted, using pCASL among ASL methods. Data from pCASL(Pseudo Continuous Arterial Spin Labeling) was acquired together with the structural image simply by changing position(labeling gap 15 mm, 170 mm) of the labeling pulse to avoid stent. Data was processed through the ASLtbx. When perfusion MRI was acquired using pCASL, it showed that the position of the conventional labeling pulse (labeling gap 24 mm) was overlapped with that of stent, which made signal intensity in right brain tissue appear as if it were void. When the labeling pulse was positioned (labeling gap 15 mm) to avoid stent, high signal intensity images were acquired. In labeling pulse (labeling gap 170 mm), the signal intensity was more reduced due to relaxation before labeled blood arrived at the imaging slice. pCASL can be stably repeated measurements because it does not use a contrast agent. And it should be selected with the appropriate image acquisition parameters for the high quality image.

스텐트 삽입술을 시행한 환자에게 ASL 방법 중 pCASL을 이용한 관류영상에서 나타난 인공물을 보고하고 이에 대한 해결방법을 제시하고자 한다. pCASL데이터는 구조적 이미지와 함께 스텐트를 피해 표지 펄스(labeling pulse)의 위치를 변경하여 획득하였다. 데이터는 ASLtbx를 이용하여 처리하였다. pCASL을 이용하여 관류영상을 획득하였을 때 기존의 표지 펄스(표지 간격(labeling gap) 24 mm)의 위치가 스텐트의 위치와 겹쳐져서 우뇌 조직의 신호강도가 비어 있는 것처럼 나타났다. 스텐트를 피해 표지 펄스(표지 간격 15 mm)를 위치시킬 때 높은 신호강도의 영상을 획득할 수 있었으며, 표지 펄스(표지 간격 170 mm)에서는 labeled 혈액이 영상절편에 도달하기 전에 이완이 되어 낮은 신호강도의 영상을 획득 하였다. pCASL은 조영제를 사용하지 않기 때문에 안정적으로 반복측정이 가능하며 양질의 영상 획득을 위해서는 알맞은 영상획득인자와 방법들이 선택되어야 한다.

Keywords

References

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