DOI QR코드

DOI QR Code

The Anti-wrinkle Effects of Cultivated Wild Ginseng Pharmacopuncture

산삼 약침의 피부 주름 개선 효과에 대한 연구

  • Lee, Yong Eun (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Lee, Hyun Jong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Kim, Jae Soo (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
  • 이용은 (대구한의대학교 한의과대학 침구의학과) ;
  • 이현종 (대구한의대학교 한의과대학 침구의학과) ;
  • 김재수 (대구한의대학교 한의과대학 침구의학과)
  • Received : 2015.05.13
  • Accepted : 2015.06.02
  • Published : 2015.06.20

Abstract

Objectives : This study was aimed to report the anti-wrinkle effects of cultivated wild ginseng pharmacopuncture. Methods : Data were collected from 23 patients who had been treated with cultivated wild ginseng pharmacopuncture for skin wrinkles. Patients were treated twice a week, for a total of 5 times. To observe the effect of the treatment, we measured the width and depth of skin wrinkles with ECOSKIN(portable fluorescent dermal diagnostic equipment). We also conducted a survey with patients to measure total satisfaction and the anti-wrinkle effect using a semantic differential scale. The evaluation was done 2 times, once before the first treatment and once 1 week after the last treatment. The relationship was measured by Wilcoxon signed rank test. Results : Skin wrinkle mean width decreased significantly from $9.45{\pm}6.60$ to $5.54{\pm}4.78$. Depth decreased significantly from $0.68{\pm}0.34$ to $0.39{\pm}0.24$ total satisfaction increased significantly from $2.46{\pm}0.743$ to $4.13{\pm}0.51$. Anti-wrinkle effect increased significantly from $2.46{\pm}0.63$ to $3.93{\pm}0.593$. Conclusions : These results suggest that cultivated wild ginseng pharmacopuncture may be effective for decreasing wrinkles.

Keywords

References

  1. Kim JS, Lee SH. Cosmetic acupuncture. Seoul : Gunja. 2011 : 3-6.
  2. Korean Dermatology Society. Dermatology. Seoul : Yeomoongak. 2001 : 8-9, 409, 533-5.
  3. Seong EJ, Kim HY, Ahn MS, Kim HY, Jo EH, Park MC. Treatment of wrinkles with oriental medicine. J Korean Medical Ophthalmol Otolaryngol Dermatol. 2008 ; 21(3) : 184-99.
  4. Choi JH, Choi JW, Park SY, Kim JH, Jeong MY. Effects of Lycii Fructus Extracts(LFE) on skin whitening and elasticity using melanoma cells. J Korean Medical Ophthalmol Otolaryngol Dermatol. 2014 ; 27(1) : 58-67.
  5. Hwangbo M, Roh SS, Seo HS. Effects of dendrobii herba and punica granatum extract on the antioxidant, anti-inflammatory, anti-wrinkle and whitening. J Korean Medical Ophthalmol Otolaryngol Dermatol. 2010 ; 23(3) : 11-32.
  6. Yang WM, Kim HM, Chang MS et al. Effects of ethanol extract of nelumbo nucifera leaves on anti-oxidation and type I procollagen expression in CCD-986sk cells. The Journal of Herbal Formula Science. 2006 ; 14(2) : 67-75.
  7. So SH, Lee SK, Hwang EI et al. Mechanisms of Korean red ginseng and herb extracts(KTNG0345) for anti-wrinkle activity. J Ginseng Res. 2008 ; 32(1) : 39-47. https://doi.org/10.5142/JGR.2008.32.1.039
  8. Lee JH, Lee KM, Kim JS, Jung TY, Lim SH. Anti-wrinkle effects of Cervi Pantotrichum Cornu pharmacopuncture solution. The Acupuncture. 2010 ; 27(4) : 1-8.
  9. Lee SN, Kim MG, Kim MH et al. Effects of Yukmigeehwang-hwan pharmacopuncture extracts on the collagenase activity and procollagen synthesis in HS68 human fibroblasts and tyrosinase activity. The Acupuncture. 2011 ; 28(1) : 39-46.
  10. Lee KH. Effects of Albizziae Cortex pharmacopuncture extracts on the collagenase activity and procollagen synthesis in HS68 human fibroblasts and tyrosinase activity. The Acupuncture. 2011 ; 28(2) : 125-31.
  11. Kwon NH, Kim CY, Shin YJ, Seo S, Song JH, Baek YH. Clinical study on facial skin furrow measurement changes after Miso facial rejuvenation acupuncture. The Acupuncture. 2009 ; 26(6) : 133-40.
  12. Yun YH, Cho SP, Choi IH. Correction of nasolabial fold with needle embedding therapy. J Korean Medical Ophthalmol Otolaryngol Dermatol. 2011 ; 24(3) : 154-61.
  13. Park HI, Yang HJ, Lim CS, Cho SP, Park SK, Lee KH. Subcision acupuncture for facial wrinkles: a case study of 8 patients. The Acupuncture. 2014 ; 31(2) : 165-71. https://doi.org/10.13045/acupunct.2014034
  14. Park JM. Study of acupuncture technique in cosmetic treatment-clinical application and effectiveness. Journal of Society of Korean Medicine for Obesity Research. 2007 ; 7(1) : 107-15.
  15. Kim YG, Sumiyoshi M, Sakanaka M, Kimura Y. Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skin aging in hairless mice. European J of Pharmacology. 2009 ; 602(1) : 148-56. https://doi.org/10.1016/j.ejphar.2008.11.021
  16. Cho SY, Won CH, Lee DH et al. Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study. Jounal of Medicinal Food. 2009 ; 12(6) : 1252-9. https://doi.org/10.1089/jmf.2008.1390
  17. Korean Acupuncture & Moxibustion Society Textbook Complication Committee. The acupuncture and moxibustion medicine. Seoul : Jipmoondang. 2012 : 412-6.
  18. Lee KW. Hwangjenaekyung-somun. Seoul : Yeogang. 2007 : 893-900.
  19. Korean Herbalogy Society. Herbalogy. Seoul : Young-lim. 2010 : 573-6.
  20. Jeong HS, Lim CS, Cha BC, Choi SH, Kwon KR. Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng. J of Pharmacopuncture. 2010 ; 13(1) : 63-77. https://doi.org/10.3831/KPI.2010.13.1.063
  21. Lee EH, Cho SY, Kim SJ, Shin ES, Chang HK, Lee TR. Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2. J Invest Dermatol. 2003 ; 121(3) : 607-13. https://doi.org/10.1046/j.1523-1747.2003.12425.x
  22. Choi S. Epidermis proliferative effect of the Panax ginseng ginsenoside Rb2. Arch Pharm Res. 2002 ; 25(1) : 71-6. https://doi.org/10.1007/BF02975265
  23. Kim SJ, Kang BY, Cho SY et al. Compund K induces expression of hyaluronan synthetase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin. Biochem and Biophysical Research Communications. 2004 ; 316(2) : 348-55. https://doi.org/10.1016/j.bbrc.2004.02.046
  24. Lee JH, Lee BS, Yang MS, Byun BS, Kim WG, Kim BH. Prevention of photoaging and wrinkle formation in hairless mice dorsal skin by AP3-03. Korean J Food Sci Technol. 2005 ; 37(1) : 986-96.
  25. Lee HJ, Kim SR, Kim JS, Moon CJ, Bae CS, Jang JS. The effect of red ginseng on ultraviolet B-induced skin damages in mouse. J Ginseng Res. 2006 ; 30(4) : 194-8. https://doi.org/10.5142/JGR.2006.30.4.194
  26. Kim MW, Lim HH, Song YK. Anti-obesity effect of wild ginseng complex pharmacopuncture on adipocyte and high fat diet-induced obese C57BL/6J mice. J of Korean Rehabilitation Medicine. 2012 ; 22(2) : 67-90.
  27. Dan SG. Shinnong-bonchogyung-gyojung. Gilim : Gwahakgisul. 1988 : 150.
  28. Jung C, Jung JH, Lee MS. A clinical study of immune pharmacopunturology. Chungnam : Kyunglak-Yihacksa. 2011 : 518-20.

Cited by

  1. 한의학 학술지에 게재된 대상포진 임상논문에서 사용된 약침에 관한 고찰 vol.29, pp.1, 2015, https://doi.org/10.6114/jkood.2016.29.1.113