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Anti-aging Joobang(酒方)s in Dongeuibogam : Identification of candidates by text mining

『동의보감(東醫寶鑑)』에서 발굴한 항노화 효능을 가진 주방(酒方) 후보군에 대한 연구

  • Lyu, Jeong-Ah (Division of Humanities and Social Medicine, School of Korean Medicine, Pusan National University) ;
  • Baek, Jin-Ung (Division of Humanities and Social Medicine, School of Korean Medicine, Pusan National University)
  • 류정아 (부산대학교 한의학전문대학원 인문사회의학부) ;
  • 백진웅 (부산대학교 한의학전문대학원 인문사회의학부)
  • Received : 2015.04.02
  • Accepted : 2015.05.12
  • Published : 2015.05.25

Abstract

Objectives : To investigate the anti-aging effects of Joobang(酒方) on Dongeuibogam Methods : We analyzed the effect of 27 Joobang(酒方)s on Dongeuibogam and finally extracted 11 Joobang(酒方)s, which have anti-aging effects. Results & Conclusions : 1. We finally selected 12 terms of Joobang(酒方)'s anti-aging effect on Dongeuibogam. 2. We finally selected 11 Joobang(酒方)s as anti-aging candidates. 3. Twelve terms of Joobang(酒方)'s anti-aging effect and 11 candidates with anti-aging effects were classified into five categories. 4. We finally selected 17 medicinal herbs from the 11 candidates. 5. Eleven candidate anti-aging Joobang(酒方)s and 17 medicinal herbs proposed in this study have the potential to reduce the time required for experimental and clinical research for developing novel compounds with anti-aging effects.

Keywords

Acknowledgement

Supported by : 한국연구재단

References

  1. 허준 著, 동의문헌연구실 譯. 新增補對譯 東醫寶鑑. 법인문화사. 서울. 2012. p.226, 785, 802, 1063, 1145, 1160, 1485, 1488, 1519, 1531, 1638, 1684, 1773. pp.223-224, 655-656, 865-866, 1630-1631, 1855-1857. Written by Heo Jun. translaterd by laboratory of medical classics. New paralled translation text of Dongeuibogam. Seoul. Beobin publisher. 2012. p.226, 785, 802, 1063, 1145, 1160, 1485, 1488, 1519, 1531, 1638, 1684, 1773. pp.223-224, 655-656, 865-866, 1630-1631, 1855-1857.
  2. 박경련. 동의보감의 서지학적 연구. 전남대학교 박사 학위 논문. 2009. p.43. Kyung Ryun Park. (2009) A Bibliographic Study on Dongeuibogam. Doctorate thesis. Graduate School Chonnam National University. 2009. p.43.
  3. 권오민, 차웅석, 박상영, 오준호, 안상우."동의보감(東醫寶鑑)"과 "본초강목(本草綱目)"의 한국적 전유(專有)와 조선후기 의학 특징의 형성. 한국한의학연구원논문집. 2011. 17(3). p.17. Ohmin Kwon, Wungseok Cha, Sangyoung Park, Junho Oh, Sangwoo Ahn. (2011) The Appropriation of Dongeuibogam and Bencao Gangmu and the Shaping of Distinctive Korean Medicine in the late Joseon Dynasty. Korean Journal of Oriental Medicine 17(3). p.17.
  4. 김남일. 東醫寶鑑 登載의 意義와 現代的 活用. 한국한의학연구원 논문집. 2009. 15(1). p.14. Namil Kim. (2009) The Significance of Dongeuibogam Registration and Its Modern Application. Korean Journal of Oriental Medicine 15(1). p.14.
  5. 윤상득. 동의보감의 술(酒)에 대한 고찰. 경희 대학교 대학원. 석사 학위논문. 2012. p.2. Yun sang-duk. A study on the alcoholic drink on Dongeuibogam. Master thesis. Graduate School Kyunghee University. 2012. p.2.
  6. 이동우, 백진웅. 東醫寶鑑에 수록된 항노화 효능어와 이에 근거한 항노화 한약재 선별 방법론 연구. 대한한의학원전학회지. 2014. 27(2). p.45. Dongwoo Lee, Jinung Baek. A study on analyzing the terms describing anti-aging effects in Dongeuibogam to propose the methodology for selecting medicinal herbs related to anti-aging effects. Journal of Korean Medical Classics. 2014. 27(2). p.45.
  7. Brian H. May, Chuanjian Lu, Louise Bennett, Helmut M.Hugel, Charlie C.L.Xue. Evaluating the traditional Chinese literature for herbal formulae and individual herbs used for age-related dementia and memory impairment. Biogerontology. 2012. 13(3). pp.299-312. https://doi.org/10.1007/s10522-012-9375-6
  8. Lei Zhang, Yin Li, Xinfeng Guo, Brian H. May, Charlie C. L. Xue, Lihong Yang, Xusheng Liu. Text Mining of the Classical Medical Literature for Medicines That Show Potential in Diabetic Nephropathy. Evidence-Based Complementary and Alternative Medicine. 2012. Article ID 189125.
  9. MJ Choi, BT Choi, HK Shin, BC Shin, YK Han, JU Baek. (2015) Establishment of a comprehensive list of candidate anti-aging medicinal herb used in Korean medicine by text mining of the classical Korean medical literature, "Dongeuibogam", and preliminary evaluation of the anti-aging effects of these herbs. Evidence-Based Complementary and Alternative Medicine. Article ID 873185.