The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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A Study on the Blood Health Status and Nutrient Intake in Elderly Women Dwelling in Longevity Region in Jeonla Province according to Bone Mineral Density

전라도 장수지역에 거주하는 여자노인의 골밀도에 따른 생화학적 지표 및 영양섭취상태에 관한 연구

  • Oh, Se In (Dept. of Food and Nutrition, Seoil University) ;
  • Kwak, Chung Shil (Korea Institute on Aging, Seoul National University) ;
  • Lee, Mee Sook (Dept. of Food and Nutrition, Hannam University)
  • 오세인 (서일대학교 식품영양학과) ;
  • 곽충실 (서울대학교 노화고령사회연구소) ;
  • 이미숙 (한남대학교 식품영양학과)
  • Received : 2015.03.16
  • Accepted : 2015.03.30
  • Published : 2015.04.30
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Abstract

This study was conducted to investigate the dietary and other factors affecting bone mineral density (BMD) in older Korean women. A total of 340 women aged 65 to 74 were recruited from the Kugoksoondam area (Kurye, Goksung, Soonchang and Damyang counties), known as the longevity-belt region in Jeonla province, Korea. They were categorized into two groups according to bone status by T-score : a nonosteoporotic group and an osteoporotic group. Demographic characteristics were collected, as well as information on physical measurements, blood tests for biochemical indicators, health status health-related life style, dietary behavior, favorite food groups, nutrient intake and mini nutrition assessment (MNA). The results are as follows: The mean age of 185 nonosteoporotic women was 69.6 years and that of 155 osteoporotic women was 70.9 years (p<0.001). The mean T-score of the nonosteoporotic group was $-1.5mg/cm^3$ and that of theosteoporotic group was $-3.2mg/cm^3$ (p<0.001). Height and body weight in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.001, respectively). There was no significant difference in BMI, although the BMI in the nonosteoporotic group was slightly higher. Waist and hip circumferences in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.01, respectively), and the mid upper arm and calf circumferences were also significantly higher than in the osteoporotic group (p<0.001, p<0.01, respectively). The 5 m walking ability was significantly superior compared to the osteoporotic group. Serum levels did not show any significant differences between the groups and were within normal range. The serum total protein, albumin and Insulin-like growth factor (IGFs) levels of the nonosteoporotic group were significantly higher than those of the osteoporotic group (p<0.05, p<0.05, p<0.001, respectively). IGF was 104.7 ng/mL for the nonosteoporotic group and 88.1 ng/mL for the osteoporotic group. Physical activity and appetite in the nonosteoporotic group were significantly higher (p<0.01, p<0.05, respectively). The favorite food groups of the nonosteoporotic group comprised more meats and fish than those of the osteoporotic group (p<0.05, respectively). Nutrient intake was not significantly different, with the exception of niacin intake (p<0.05), but the nutrient intake of the nonosteoporotic group was slightly higher than that of the osteoporotic group. The niacin intake of the nonosteoporotic group and the osteoporotic group were 11.4 mgNE and 10.0 mgNE, corresponding to 103.6% and 90.9% of the Korean EAR, respectively. The MNA score of the nonosteoporotic group was significantly more favorable than for the osteoporotic group. In conclusion, it is necessary to maintain adequate body weight and muscle mass. Habitual physical activity may have a beneficial effect on BMD for older women. Dietary factors, such as meat and fish, higher intake of niacin rich foods and nutrient status for older women also appear to have favorable effects on bone mineral density.

Keywords

Acknowledgement

Supported by : 서일대학교

References

  1. Ahmadi SM, Mohammadi MR, Mostafavi SA, Keshavarzi S, Kooshesh SM, Joulaei H, Sarikhani Y, Peimani P, Heydari ST, Lankarani KB. 2013. Dependence of the geriatric depression on nutritional status and anthropometric indices in elderly population. Iran J Psychiatry 8:92-96
  2. Ahn KB, Kim JG, Bai KB, Lee JY. 2000. Usefulness of insulinlike growth factors in predict in reduced bone mass in natural postmenopausal women. Kor J Obstet & Gynecol 43:1813-1821
  3. Amador LF, Al Snih S, Markides KS, Goodwin JS. 2006. Weight change and mortality among elderly Mexican Americans. Aging Clin Exp Res 18:196-204 https://doi.org/10.1007/BF03324649
  4. American Diabetes Association (ADA). 2010. Diagnosis and classification of diabetes mellitus. Diabetes Care 33:S62-69 https://doi.org/10.2337/dc10-S062
  5. Anderson JJB. 1996. Nutritional advances in human bone metabolism introduction. J Nutr 126:1150S-1152S
  6. Bollwein J, Volkert D, Diekmann R, Kaiser MJ, Uter W, Vidal K, Sieber CC, Bauer JM. 2013. Nutritional status according to the mini nutritional assessment (MNA) and frailty in community dwelling older persons: A close relationship. J Nutr Health Aging 17:351-356 https://doi.org/10.1007/s12603-013-0034-7
  7. Campion EW, deLabry LO, Glynn RJ. 1988. The effect of age on serum albumin in healthy males: Report from the normotive aging study. J Gerontol 43:M18-20 https://doi.org/10.1093/geronj/43.1.M18
  8. Carmeli E, Coleman R, Reznick AZ. 2002. The biochemistry of aging muscle. Exp Gerontol 37:477-489 https://doi.org/10.1016/S0531-5565(01)00220-0
  9. Choe JS, Kwon SO, Paik HY. 2006. Nutritional status andrelated factors of the elderly in longevity areas. III. Relation among self-rated health, health-related behaviors, and nutrient intake in rural elderly. Korean J Nutr 39:286-298
  10. Cooper JK, Gardner C. 1989. Effect of aging on serum albumin. J Am Geriatr Soc 37:1039-1042 https://doi.org/10.1111/j.1532-5415.1989.tb06917.x
  11. Ennis BW, Saffel-Shrier S, Verson H. 2001. Diagnosis malnutrition in the elderly. Nurse Practitioner 26:52-65
  12. Ericksen EF, Langdahl BL. 1997. The pathogenesis of osteoporosis. Horm Res 48:78-82 https://doi.org/10.1159/000191333
  13. Freudenheim JOL, Johnson NE, Smith EL. 1986. Relationships between usual nutrient intake and bone-mineral content of 35-65 years of age: Longitudinal and cross-sectional analysis. Am J Clin Nutr 44:863-876
  14. Gordin JM, Siiteri PK, McDonald PC. 1993. Source of estrogen production in postmenopausal women. J Clin Endocrinol Metab 36:207-218
  15. Holbrook TL, Barrett-Connor E, Wingard DL. 1988. Dietary calcium intake and risk of hip fracture: 14-years prospective population study. Lancet 2:1046-1049
  16. Holbrook TL, Barrett-Connor E. 1993. The association of life time weight and weight control patterns with mineral density in an adult community. Bone & Mineral 20:141-149 https://doi.org/10.1016/S0169-6009(08)80023-2
  17. Hooshmand B, Solomon A, Kreholt I, Rusanen M, Hnninen T, Leivisk J, Winblad B, Laatikainen T, Soininen H, Kivipelto M. 2012. Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: A longitudinal study. J Intern Med 271:204-212 https://doi.org/10.1111/j.1365-2796.2011.02484.x
  18. Idler EL, Kasl SV. 1995. Self-rating of health: Do they also predict change in functional ability? J Gerontol B Psychol Sci Soc Sci 50:s344-s353
  19. Kalu DN, Liu CC, Arjmandi BH, Lie CC, Salih MA, Birnbaum RS. 1994. Effects of ovariectomy and estrogen on the serum levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3. Bone and Mineral 25:135-148 https://doi.org/10.1016/S0169-6009(08)80255-3
  20. Keller H, Ostbye T, Goy R. 2004. Nutritional risk predicts quality of life in elderly community-dwelling Canadians. J Gerontol A Bio Sci and Med Sci 59A:68-74
  21. Kerstetter JE, Allen LH. 1994. Protein intake and calcium homeostasis. Adv Nutr Res 9:167-181
  22. Kim NS, You YS, Kang CW, Choi IH. 2000. The change of osteocalcin, bone-specific alkaline phosphatase, estrogen, IGF-I, ${Ca^+}$, P and bone mineral density on osteoporosis induced by ovariectomy in rats. Korea J Vet Res 40:755-762
  23. Kim SM, Choi IH, Kim NS. 2003. Effects of safflower seeds on the serum levels of insulin-like growth factors, insulinlike growth factor binding protein-3 and BALP in osteoporosis induced-ovariectomized rats. J Vet Clin 20:263-273
  24. Koo JO, Kwak CS, Choi HM. 1991. Effects of dietary protein levels and sources on calcium and phosphorus metabolism in young Korean women. J Nutr & Health 24:124-131
  25. Korean Nutrition Society. 2010. Dietary Reference Intakes for Koreans. Seoul, Korea
  26. Korean Society for the Study of Obesity. 2000. Diagnosis and Therapy of Obesity: Asia-Pacific Area Guideline. Seoul
  27. Lacey JM, Anderson JJB, Fujita T, Yoshimoto Y, Koch GG. 1991. Correlates of cortical mass among premenopausal and postmenopausal Japanese women. J Bone Mine Res 6:651-659
  28. Lamichhane AP. 2005. Osteoporosis-an update. J Nepal Med Assoc 44:60-66
  29. Lee BK, Chang YK, Choi KS. 1992. Effect of nutrient intake on bone mineral density in postmenopausal women. Kor J Nutr 25:642-655
  30. Lee KS, Cheong HW, Kim EA, Kim KR, Oh BH, Hong CH. 2009. Nutritional risk and cognitive impairment in the elderly. Arch Gerontol Geriatrics 48:95-99 https://doi.org/10.1016/j.archger.2007.11.001
  31. Lin JT, Lane JM. 2004. Osteoporosis. Clin Orthop Relat Res 425:126-34 https://doi.org/10.1097/01.blo.0000132404.30139.f2
  32. Mazess RB, Barden HS. 1991. Bone density in premenopausal women: Effect of age, dietary intake, physical activity, smoking and birth-control pills. Am J Clin Nutr 53:132-142
  33. Mcguigan FE, Murray L, Gallagher A, Davey-Smith G, Neville CE, Van't Hof R, Boreham C, Ralston SH. 2002. Genetic and environmental determinants of peak bone mass in young man and women. J Bone Miner Res 17:1273-1279 https://doi.org/10.1359/jbmr.2002.17.7.1273
  34. Mckay HA, Petit MA, Khan KM, Schutz RW. 2000. Lifestyle determinants of bone mineral: A comparison between prepubertal Asian- and Caucasian-Canadian boys and girls. Calcif Tissue Int 66:320-324 https://doi.org/10.1007/s002230010067
  35. Metz JA, Anderson JJB, Gallagher Jr PN. 1993. Intakes of calcium, phosphorus, and protein and physical activity level are related to radial bone mass in young adult women. Am J Clin Nutr 58:537-542
  36. Ministry of Health and Welfare. 2010. 2009 National Health Statistics-The 3rd Year of the Fouth National Health and Nutrition Examination Survey. Korea Center for Disease Control and Prevention, Seoul
  37. Ministry of Health and Welfare. 2013. 2012 National Health Statistics-The 3rd Year of the Fifth National Health and Nutrition Examination Survey. Korea Center for Disease Control and Prevention, Seoul
  38. Montlahuc C, Soumare A, Dufouil C, Berr C, Dartigues JF, Poncet M, Tzourio C, Alperovotch A. 2011. A self-rated health and risk of incident dementia: A community-based elderly cohort, the 3C study. Neurology 77:1457-1411 https://doi.org/10.1212/WNL.0b013e31823303e1
  39. Newman AB, Yanez D, Harris T, Duxbury A, Enright PL, Fried LP. 2001. Weight change in old age and its association with mortality. J Am Geriatr Soc 49:1309-1318 https://doi.org/10.1046/j.1532-5415.2001.49258.x
  40. Oh SI, Lee HS, Lee MS, Kim CI, Kwon IS, Park SC. 2002. Some factors affecting bone mineral status of postmenopausal women. Kor J Comm Nutr 7:121-129
  41. Park JY, Choi MY, Lee SH, Choi YH, Park YY. 2011. The Association between bone mineral density, bone turnover markers, and nutrient intake in pre- and postmenopausal women. Kor J Nutr 44:29-40 https://doi.org/10.4163/kjn.2011.44.1.29
  42. Ramsdale SJ, Bassey EJ, Pye DJ. 1994. Dietary calcium intake related to bone mineral density in premenopausal women. British J Nutr 71:77-84 https://doi.org/10.1079/BJN19940112
  43. Riggs BL, Melton LJ. 1992. The prevention and treatment of osteoporosis. N Engl J Med 327:620-627 https://doi.org/10.1056/NEJM199208273270908
  44. Saarelainen J, Kiviniemi V, Kroer H, Tuppurainen M, Niskanen L, Jurvelin J, Honkanen R. 2012. Body mass index and bone loss among postmenopausal women: The 10-year follow-up of the OSTPRE cohort. J Bone Miner Metab 30:208-216 https://doi.org/10.1007/s00774-011-0305-5
  45. Sieber CC. 2006. Nutritional screening tools - How dose the MNA compare? Proceeding of the Session Held in Chicago May 2-3, 2006 (15 Years of Mini Nutritional Assessment). J Nutr Health & Aging 10:488-492
  46. Suleiman S, Nelson M, Li F, Buxton-Thomas M, Moniz C. 1997. Effect of calcium intake and physical activity level on bone mass and turnover in healthy, white, postmenopausal women. Am J Clin Nutr 66:937-943
  47. Vuorisalmi M, Lintonen T, Jylha M. 2006. Comparative vs global self-rated health: Associations with age and functional ability. Aging Clin Exp Res 18:211-217 https://doi.org/10.1007/BF03324651
  48. Wardlaw GH. 1996. Putting body weight and osteoporosis into perspective. Am J Clin Nutr 63:433S-436S
  49. Yatabe MS, Taguchi F, Ishida I, Sato A, Kameda T, Ueno S, Takano K, Watanabe T, Sanada H, Yatabe J. 2013. Mini nutritional assessment as a useful method of predicting the development of pressure ulcers in elderly patients. J Am Geriatr Soc 61:1698-170 https://doi.org/10.1111/jgs.12455