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유기 자외선 흡수제의 조합과 용해도에 따른 자외선 차단 효율의 비교 및 안정성에 관한 연구

Stability and Sun Protection Efficacy of Sunscreens Based on the Solubility and a Combination of Organic UV Absorbers

  • 연제영 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 홍승덕 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 최세범 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 김타곤 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 이청희 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 이상길 (한불화장품(주) 기술연구원 화장품연구소) ;
  • 표형배 (한불화장품(주) 기술연구원 화장품연구소)
  • Yeon, Jae Young (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Hong, Seung Deok (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Choi, Se Bum (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Kim, Ta Gon (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Lee, Cheong Hee (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Lee, Sang Gil (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.) ;
  • Pyo, Hyeong Bae (Cosmetic Research Institute, Hanbul Cosmetics Co., Ltd.)
  • 투고 : 2015.06.26
  • 심사 : 2015.09.18
  • 발행 : 2015.09.30

초록

본 연구에서는 유기 자외선 흡수제와 오일들 간의 용해도에 따른 자외선 차단제의 안정성과 유기 자외선 흡수제의 조합에 따른 이들의 자외선 차단 효율 변화를 조사하여 보다 안정하고 효율이 높은 자외선 차단제품 개발에 도움이 되고자 하였다. 그 결과 오일의 종류, 농도 그리고 보관 조건에 따라서 유기 자외선 흡수제의 용해도 및 안정성이 다양하게 관찰되었으며, 이러한 현상은 에멀젼상에서도 자외선 차단지수에 영향을 나타냄을 확인하였다. 또한 유기 자외선 흡수제의 조합에 따라 다양한 자외선 흡광도가 측정되었으며, 조합 시 각각의 자체 흡광도보다 높은 시너지 효과를 나타내는 성분이 있었고, 특정 성분과의 조합 시에만 시너지 효과가 나타나는 경우도 있었다. 보관 조건에 따라서도 자외선 흡광도는 상이하게 측정되어, 자외선 차단 효율에 영향을 나타내는 다양한 변수가 있음을 확인할 수 있었다.

In this study, we have investigated the stability of sunscreens based on the solubility of organic UV absorbers in the oil and sun protection efficacy of the products composed of a combination of organic UV absorbers to develop more stable and efficient sunscreen products. Results showed that the solubility of the organic UV absorber and stability were varied depending on the type, storage conditions and concentration of oil. It was also observed from the products in the emulsion type. Various UV absorbances were determined to the products composed of the combination of organic UV absorbers. In some combinations, a synergistic effect was observed to make an increase in absorbance compared to a single component. In other cases, specific synergistic effect was displayed only when combined with the particular component. In addition, the storage condition also affected the sunscreen efficacy. In conclusion, this study confirmed that there are various factors which could affect the UV-blocking efficiency of sunscreen products.

키워드

참고문헌

  1. C. I. Park, T. J. Kang, and S. J. Lee, Effects of rheological properties of emulsions having sunscreening agent on sun protection efficacy, Korean Chem. Eng. Res., 41(5), 598 (2003).
  2. C. L. Hexsel, S. D. Bangert, A. A. Hebert, and H. W. Lim, Current sunscreen issues: 2007 food and drug administration sunscreen labelling recommendations and combination sunscreen/insect repellent products, J. Am. Acad. Dermatol., 59(2), 316 (2008). https://doi.org/10.1016/j.jaad.2008.03.038
  3. D. E. Heck, D. R. Gerecke, A. M. Vetrano, and J. D. Laskin, Solar ultraviolet radiation as a trigger of cell signal transduction, Toxicol. Appl. Pharmacol., 195(3), 288 (2004). https://doi.org/10.1016/j.taap.2003.09.028
  4. A. Mahns, R. Wolber, F. Stab, L. O. Klotz, and H. Sies, Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis, Photochem. Photobiol. Sci., 3(3), 257 (2004). https://doi.org/10.1039/b309067a
  5. B. L. Diffey, Sources and measurement of ultraviolet radiation, Methods, 28(1), 4 (2002). https://doi.org/10.1016/S1046-2023(02)00204-9
  6. C. Huang, W. Ma, and Z. Dong, Signal transduction through atypical PKCs, but not the EGF receptor, is necessary for UVC induced AP-1 activation in immortal murine cells, Oncogene, 14(16), 1945 (1997). https://doi.org/10.1038/sj.onc.1201056
  7. K. Berg-Schultz, Ch. Mendrok, F. Sit, and R. Jermann, Formulating high SPF sun care products with a liquid-mineral UV filter, SOFW-Journal, 131(7), 9 (2005).
  8. S. C. Kim, K. D. Nam, and H. W. Lee, Development and efficiency-stabilization of UV blocking agents used to skincare, J. Korean Oil Chemists' Soc., 12(2), 157 (1995).
  9. J. P. Hewitt, The influence of emollients on dispersion of physical sunscreens, Drug and Cosmetic Industry, 159(3), 62 (1996).
  10. Y. S. Kang, K. Y. Gyeong, M. J. Rang, D. H. Bae, Y. G. Lee, W. G. Cho, S. G. Choi, and S. G. Han, The science of cosmetic, household and health care product, ed. Y. H. Lee, 1, 291, Shin Kwang Pub., Seoul, Korea (2008).
  11. J. H. Jeong, M. J. Kim, and Y. G. Lee, A study on the sun protection factor change according to organic UV-filters combination in sunscreen, J. Kor. Soc. Cosm., 5(2), 115 (2009).
  12. J. Y. Yeon, J. M. Seo, J. T. Bae, C. H. Lee, S. G. Lee, H. B. Pyo, and J. T. Hong, A study on the factors that influence the sun protection factor(SPF) and protection factor of UV-A(PA) in sunscreen, J. Korean Oil Chemists' Soc., 31(3), 422 (2014). https://doi.org/10.12925/jkocs.2014.31.3.422
  13. S. Y. Ahn, J. H. Bae, H. K. Lee, S. J. Moon, and I. S. Chang, Improvement of in vitro sun protection factor measurement, J. Soc. Cosmet. Scientists Korea, 30(1), 129 (2004).
  14. J. C. Yang, In vitro SPF measurement of sunscreen agents in cosmetics, J. Korean Oil Chemists' Soc., 27(3), 370 (2010).
  15. K. H. Son, Y. O. Kim, J. P. Lee, S. J. Yang, O. J. Baek, W. H. Kim, J. G. Kim, M. Y. Heo, S. S. Choi, and J. G. Lee, Studies on the evaluation of efficacy of functional cosmetics(I)-studies on the in vitro SPF test method of sunscreen products, J. Soc. Cosmet. Scientists Korea, 28(3), 171 (2002).
  16. I. V. Reeth, S. Marchioretto, F. Dahman, A. Desmedt, and A. Dupont, Silicones: enhanced protection across personal care applications, IFSCC, Cannes, France, 14 (1998).
  17. K. Berg-Schultz, Ch. Mendrok, F. Sit, and R. Jermann, Formulating high SPF sun care products with a liquid-mineral UV filter, SOFW-Journal, 131(7), 9 (2005).