DOI QR코드

DOI QR Code

The Influence of Asian Dust, Haze, Mist, and Fog on Hospital Visits for Airway Diseases

  • Park, Jinkyeong (Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Myoung Nam (Department of Internal Medicine and Environmental Health Center, Kangwon National University Hospital, Kangwon National University School of Medicine) ;
  • Hong, Yoonki (Department of Internal Medicine and Environmental Health Center, Kangwon National University Hospital, Kangwon National University School of Medicine) ;
  • Kim, Woo Jin (Department of Internal Medicine and Environmental Health Center, Kangwon National University Hospital, Kangwon National University School of Medicine)
  • 투고 : 2014.12.09
  • 심사 : 2015.07.15
  • 발행 : 2015.10.30

초록

Background: Asian dust is known to have harmful effects on the respiratory system. Respiratory conditions are also influenced by environmental conditions regardless of the presence of pollutants. The same pollutant can have different effects on the airway when the air is dry compared with when it is humid. We investigated hospital visits for chronic obstructive pulmonary disease (COPD) and asthma in relation to the environmental conditions. Methods: We conducted a retrospective study using the Korean National Health Insurance Service claims database of patients who visited hospitals in Chuncheon between January 2006 and April 2012. Asian dust, haze, mist, and fog days were determined using reports from the Korea Meteorological Administration. Hospital visits for asthma or COPD on the index days were compared with the comparison days. We used two-way case-crossover techniques with one to two matching. Results: The mean hospital visits for asthma and COPD were $59.37{\pm}34.01$ and $10.04{\pm}6.18$ per day, respectively. Hospital visits for asthma significantly increased at lag0 and lag1 for Asian dust (relative risk [RR], 1.10; 95% confidence interval [CI], 1.01-1.19; p<0.05) and haze (RR, 1.13; 95% CI, 1.06-1.22; p<0.05), but were significantly lower on misty (RR, 0.89; 95% CI, 0.80-0.99; p<0.05) and foggy (RR, 0.89; 95% CI, 0.84-0.93; p<0.05) days than on control days. The hospital visits for COPD also significantly increased on days with Asian dust (RR, 1.29; 95% CI, 1.05-1.59; p<0.05), and were significantly lower at lag4 for foggy days, compared with days without fog (RR, 0.85; 95% CI, 0.75-0.97; p<0.05). Conclusion: Asian dust showed an association with airway diseases and had effects for several days after the exposure. In contrast to Asian dust, mist and fog, which occur in humid air conditions, showed the opposite effects on airway diseases, after adjusting to the pollutants. It would require more research to investigate the effects of various air conditions on airway diseases.

키워드

참고문헌

  1. Csavina J, Field J, Taylor MP, Gao S, Landazuri A, Betterton EA, et al. A review on the importance of metals and metalloids in atmospheric dust and aerosol from mining operations. Sci Total Environ 2012;433:58-73. https://doi.org/10.1016/j.scitotenv.2012.06.013
  2. Ewing SA, Christensen JN, Brown ST, Vancuren RA, Cliff SS, Depaolo DJ. Pb isotopes as an indicator of the Asian contribution to particulate air pollution in urban California. Environ Sci Technol 2010;44:8911-6. https://doi.org/10.1021/es101450t
  3. Park JW, Lim YH, Kyung SY, An CH, Lee SP, Jeong SH, et al. Effects of ambient particulate matter on peak expiratory flow rates and respiratory symptoms of asthmatics during Asian dust periods in Korea. Respirology 2005;10:470-6. https://doi.org/10.1111/j.1440-1843.2005.00728.x
  4. Watanabe M, Y amasaki A, Burioka N, Kurai J, Yoneda K, Yoshida A, et al. Correlation between Asian dust storms and worsening asthma in Western Japan. Allergol Int 2011;60:267-75. https://doi.org/10.2332/allergolint.10-OA-0239
  5. Chiu HF, Tiao MM, Ho SC, Kuo HW, Wu TN, Yang CY. Effects of Asian dust storm events on hospital admissions for chronic obstructive pulmonary disease in Taipei, Taiwan. Inhal Toxicol 2008;20:777-81. https://doi.org/10.1080/08958370802005308
  6. Tam WW, Wong TW, Wong AH, Hui DS. Effect of dust storm events on daily emergency admissions for respiratory diseases. Respirology 2012;17:143-8. https://doi.org/10.1111/j.1440-1843.2011.02056.x
  7. Pauwels RA, B uist AS, Calverley PM, Jenkins CR, Hurd SS; GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001;163:1256-76. https://doi.org/10.1164/ajrccm.163.5.2101039
  8. Handzel ZT. Effects of environmental pollutants on airways, allergic inflammation, and the immune response. Rev Environ Health 2000;15:325-36.
  9. Muhlfeld C, Rothen-Rutishauser B, Blank F, Vanhecke D, Ochs M, Gehr P. Interactions of nanoparticles with pulmonary structures and cellular responses. Am J Physiol Lung Cell Mol Physiol 2008;294:L817-29. https://doi.org/10.1152/ajplung.00442.2007
  10. Sapey E, Stockley RA. COPD exacerbations. 2: aetiology. Thorax 2006;61:250-8. https://doi.org/10.1136/thx.2005.041822
  11. Chauhan AJ, Johnston SL. Air pollution and infection in respiratory illness. Br Med Bull 2003;68:95-112. https://doi.org/10.1093/bmb/ldg022
  12. Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet 2007;370:786-96. https://doi.org/10.1016/S0140-6736(07)61382-8
  13. Chung YS, Ki m HS, Yoon MB. Observations of visibility and chemical compositions related to fog, mist and haze in South Korea. Water Air Soil Pollut 1999;111:139-57. https://doi.org/10.1023/A:1005077415764
  14. Lumb AB. Nun n's applied respiratory physiology. 7th ed. London: Elsevier Health Sciences; 2012.
  15. Gyan K, Henr y W, Lacaille S, Laloo A, Lamsee-Ebanks C, McKay S, et al. African dust clouds are associated with increased paediatric asthma accident and emergency admissions on the Caribbean island of Trinidad. Int J Biometeorol 2005;49:371-6. https://doi.org/10.1007/s00484-005-0257-3
  16. Hackney JD, Linn WS, Avol EL. Potential risks to human respiratory health from “acid fog”: evidence from experimental studies of volunteers. Environ Health Perspect 1985;63:57-61. https://doi.org/10.1289/ehp.856357
  17. Kanatani KT, Ito I, Al-Delaimy WK, Adachi Y, Mathews WC, Ramsdell JW, et al. Desert dust exposure is associated with increased risk of asthma hospitalization in children. Am J Respir Crit Care Med 2010;182:1475-81. https://doi.org/10.1164/rccm.201002-0296OC
  18. Lee JT, Son JY, Cho YS. A comparison of mortality related to urban air particles between periods with Asian dust days and without Asian dust days in Seoul, Korea, 2000-2004. Environ Res 2007;105:409-13. https://doi.org/10.1016/j.envres.2007.06.004
  19. Garcia-Aymer ich J, Tobias A, Anto JM, Sunyer J. Air pollution and mortality in a cohort of patients with chronic obstructive pulmonary disease: a time series analysis. J Epidemiol Community Health 2000;54:73-4. https://doi.org/10.1136/jech.54.1.73
  20. Higgins BG, Francis HC, Yates CJ, Warburton CJ, Fletcher AM, Reid JA, et al. Effects of air pollution on symptoms and peak expiratory flow measurements in subjects with obstructive airways disease. Thorax 1995;50:149-55. https://doi.org/10.1136/thx.50.2.149
  21. Kan H, Chen B. A case-crossover analysis of air pollution and daily mortality in Shanghai. J Occup Health 2003;45:119-24. https://doi.org/10.1539/joh.45.119
  22. Schwartz J, Dockery DW. Increased mortality in Philadelphia associated with daily air pollution concentrations. Am Rev Respir Dis 1992;145:600-4. https://doi.org/10.1164/ajrccm/145.3.600
  23. Tellez-Rojo MM, Romieu I, Ruiz-Velasco S, Lezana MA, Hernandez-Avila MM. Daily respiratory mortality and PM10 pollution in Mexico City: importance of considering place of death. Eur Respir J 2000;16:391-6. https://doi.org/10.1034/j.1399-3003.2000.016003391.x
  24. Arbex MA, de Souza Conceicao GM, Cendon SP, Arbex FF, Lopes AC, Moyses EP, et al. Urban air pollution and chronic obstructive pulmonary disease-related emergency department visits. J Epidemiol Community Health 2009;63:777-83. https://doi.org/10.1136/jech.2008.078360
  25. Ko FW, Hui DS. Air pollution and chronic obstructive pulmonary disease. Respirology 2012;17:395-401. https://doi.org/10.1111/j.1440-1843.2011.02112.x
  26. Anto JM, Ver meire P, Vestbo J, Sunyer J. Epidemiology of chronic obstructive pulmonary disease. Eur Respir J 2001;17: 982-94. https://doi.org/10.1183/09031936.01.17509820
  27. Holguin F. Traffic related exposures and lung function in adults. Thorax 2007;62:837-8. https://doi.org/10.1136/thx.2007.078410
  28. Long W, Tate RB, Neuman M, Manfreda J, Becker AB, Anthonisen NR. Respiratory symptoms in a susceptible population due to burning of agricultural residue. Chest 1998;113: 351-7. https://doi.org/10.1378/chest.113.2.351
  29. Rodriguez-Roisin R. Toward a consensus definition for COPD exacerbations. Chest 2000;117(5 Suppl 2):398S-401S. https://doi.org/10.1378/chest.117.2.398
  30. Sethi S, Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med 2008; 359:2355-65. https://doi.org/10.1056/NEJMra0800353

피인용 문헌

  1. Differences in the effects of Asian dust on pulmonary function between adult patients with asthma and those with asthma–chronic obstructive pulmonary disease overlap syndrome vol.11, pp.None, 2015, https://doi.org/10.2147/copd.s97460
  2. A comparison of health impacts assessment for PM10 during two successive years in the ambient air of Kermanshah, Iran vol.7, pp.5, 2015, https://doi.org/10.1016/j.apr.2016.04.004
  3. Hospital admissions in Iran for cardiovascular and respiratory diseases attributed to the Middle Eastern Dust storms vol.24, pp.20, 2017, https://doi.org/10.1007/s11356-017-9298-5
  4. Environmental exposures and chronic obstructive pulmonary disease vol.13, pp.3, 2015, https://doi.org/10.1007/s13273-017-0027-4
  5. Impact of Middle Eastern Dust storms on human health vol.8, pp.4, 2015, https://doi.org/10.1016/j.apr.2016.11.005
  6. Epidemiological study of PM 2.5 and risk of COPD-related hospital visits in association with particle constituents in Chuncheon, Korea vol.13, pp.None, 2015, https://doi.org/10.2147/copd.s149469
  7. Chronic obstructive pulmonary diseases related to outdoor PM10, O3, SO2, and NO2 in a heavily polluted megacity of Iran vol.25, pp.18, 2018, https://doi.org/10.1007/s11356-018-1902-9
  8. Health Effects of Asian Dust Events: A Literature Review Update of Epidemiological Evidence vol.74, pp.None, 2019, https://doi.org/10.1265/jjh.19010
  9. Air Pollution in the Asia-Pacific Region. A Joint Asian Pacific Society of Respirology/American Thoracic Society Perspective vol.199, pp.6, 2015, https://doi.org/10.1164/rccm.201804-0673pp
  10. Air pollution in the Asia‐Pacific Region vol.24, pp.5, 2015, https://doi.org/10.1111/resp.13531
  11. Air quality modeling for health risk assessment of ambient PM10, PM2.5 and SO2 in Iran vol.25, pp.5, 2019, https://doi.org/10.1080/10807039.2018.1487277
  12. Global Health Impacts of Dust Storms: A Systematic Review vol.15, pp.None, 2015, https://doi.org/10.1177/11786302211018390