한국생산제조학회지 (Journal of the Korean Society of Manufacturing Technology Engineers)

  • 제24권5호
  • /
  • Pages.481-488
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  • 2015
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  • 2508-5093(pISSN)
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  • 2508-5107(eISSN)
한국생산제조학회 (The Korean Society of Manufacturing Technology Engineers)
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CTO 괴사를 위한 고강도 집속 초음파의 음향학적 특성

Acoustic Characteristics of High Intensity Focused Ultrasound for Necrosis of CTO

  • 투고 : 2015.08.26
  • 심사 : 2015.10.02
  • 발행 : 2015.10.15
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초록

It is difficult to see a therapeutic effect from cardiovascular disease treatment methods in the case of a hardened chronic total occlusion (CTO), owing to the calcification of the deposition materials. However, lesion cells, such as CTOs, can be selectively necrotized without affecting the normal tissue using high-intensity ultrasound focused on one point. In this study, a phantom CTO was necrotized by a high-intensity focused ultrasound (HIFU) energy system, and the acoustic characteristics in the focal region were analyzed. An experimental HIFU device was constructed to discover the appropriate conditions for the necrosis of a phantom CTO. The transfer characteristics of the ultrasound changed in the focal region by the density difference of the phantom CTO. These changes were acoustically analyzed to choose the available frequency band for each density. On-off temperature control in the focal region was applied to prevent rapid temperature rises, which would otherwise affect normal tissue.

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참고문헌

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