Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
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The Rare and Challenging Presentation of Gastric Cancer during Pregnancy: A Report of Three Cases

  • Pacheco, Sergio (Digestive Surgery Department, Pontificia Universidad Catolica de Chile) ;
  • Norero, Enrique (Digestive Surgery Department, Pontificia Universidad Catolica de Chile) ;
  • Canales, Claudio (Digestive Surgery Unit, Hospital Dr. Eduardo Pereira, Universidad de Valparaiso) ;
  • Martinez, Jose Miguel (Digestive Surgery Unit, Hospital Dr. Eduardo Pereira, Universidad de Valparaiso) ;
  • Herrera, Maria Elisa (Esophagogastric Surgery Unit, Hospital Dr. Sotero del Rio) ;
  • Munoz, Carolina (Esophagogastric Surgery Unit, Hospital Dr. Sotero del Rio) ;
  • Jarufe, Nicolas (Digestive Surgery Department, Pontificia Universidad Catolica de Chile)
  • Received : 2016.08.29
  • Accepted : 2016.11.10
  • Published : 2016.12.31
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Abstract

Pregnancy-associated gastric cancer is extremely rare. In many cases, it is diagnosed at an advanced stage because the symptoms during pregnancy are generally overlooked. We report three cases of gastric cancer during pregnancy with various outcomes. The first case included a patient with stage IV gastric cancer who received palliative chemotherapy. This patient had a preterm birth and died 7 months after diagnosis. The second case received neoadjuvant chemotherapy during pregnancy and a total gastrectomy was performed after delivery. She then received adjuvant chemoradiotherapy. This patient developed pulmonary metastasis and died of recurrence 41 months after surgery. In the third case, a distal subtotal gastrectomy was performed at week 14 of pregnancy, with no complications. The patient received adjuvant chemoradiotherapy. She is currently without recurrence 14 months after surgery. In patients with pregnancy-associated gastric cancer, treatment decisions are predominantly influenced by clinical stage and gestational age at diagnosis.

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References

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