Applied Microscopy

Korean Society of Microscopy (한국현미경학회)
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Light-Microscopy-Based Sparse Neural Circuit Reconstruction: Array Tomography and Other Methods

  • Rah, Jong-Cheol (Korea Brain Research Institute, Laboratory of Neurophysiology)
  • Received : 2016.12.21
  • Accepted : 2016.12.23
  • Published : 2016.12.30
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Abstract

Efficient neural circuit reconstruction requires sufficient lateral and axial resolution to resolve individual synapses and map a large enough volume of brain tissue to reveal the molecular identity and origin of these synapses. Sparse circuit reconstruction using array tomography meets many of these requirements but also has some limitations. In this minireview, the advantages and disadvantages of applicable imaging techniques will be discussed.

Keywords

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