Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea

최근 국내에서 유행하는 돼지 유행성 설사 바이러스 nucleocapsid 유전자의 다양성 및 계통 분석

  • Kim, Kiju (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Park, Yookyung (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Park, Bokyung (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Truong, Quang Lam (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Park, Soyeon (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Kim, Jaehun (College of Veterinary Medicine, Jeju National University) ;
  • Hahn, Tae-Wook (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • 김기주 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 박유경 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 박보경 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 람쯩꽝 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 박소연 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 김재훈 (제주대학교 수의과대학) ;
  • 한태욱 (강원대학교 수의과대학 및 동물의학종합연구소)
  • Received : 2016.01.14
  • Accepted : 2016.03.02
  • Published : 2016.03.31
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Abstract

Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in Korea, and these outbreaks have since continuously occurred. In the present study, we determined the full-length nucleocapsid (N) gene sequences of three Korean PEDV field isolates collected in 2014-2015. Sequence and phylogenetic analysis of N genes revealed that recent prevalent Korean PEDV isolates were very closely related to the US PEDV isolates in 2013. Interestingly, the phylogenetic tree based on the nucleotide sequencing of the PEDV N gene was similar to the tree topology of the PEDV complete genomes. Therefore, our data provide a better understanding of the genetic diversity and contribute to the accurate diagnosis and development of vaccines against PEDV.

Keywords

References

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