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Effect of Cervical Interlaminar Epidural Steroid Injection: Analysis According to the Neck Pain Patterns and MRI Findings

  • Choi, Ji Won (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Hyung Woo (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Jin Young (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Won Il (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Eun Kyung (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Chang, Choo Hoon (Zein (ZEropaIN) Pain Treatment Clinic) ;
  • Yang, Jae Young (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Sim, Woo Seog (Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2016.01.11
  • Accepted : 2016.02.25
  • Published : 2016.04.01

Abstract

Background: It is widely accepted that cervical interlaminar steroid injection (CIESI) is more effective in treating radicular pain than axial neck pain, but without direct comparison. And the differences of effect after CIESI according to MRI findings are inconsistent. In this retrospective study, we evaluated the therapeutic response of CIESI according to pain sites, durations, MRI findings, and other predictive factors altogether, unlike previous studies, which evaluated them separately. Methods: The medical records of 128 patients who received fluoroscopy guided CIESI were analyzed. We evaluated the therapeutic response (more than a 50% reduction on the visual analog scale [VAS] by their second visit) after CIESI by (1) pain site; neck pain without radicular pain/radicular pain with or without neck pain, (2) pain duration; acute/chronic (more than 6 month), and (3) findings of MRI; herniated intervertebral disc (HIVD)/spinal stenosis, respectively and altogether. Results: Eighty-eight patients (68%) responded to CIESI, and there were no significant differences in demographic data, initial VAS score, or laboratory findings. And there were no significant differences in the response rate relating to pain site, pain duration, or MRI findings, respectively. In additional analysis, acute radicular pain with HIVD patients showed significantly better response than chronic neck pain with spinal stenosis (P = 0.04). Conclusions: We cannot find any sole predictive factor of therapeutic response to the CIESI. But the patients having acute radicular pain with HIVD showed the best response, and those having other chronic neck pain showed the worst response to CIESI.

Keywords

References

  1. Rowlingson JC, Kirschenbaum LP. Epidural analgesic techniques in the management of cervical pain. Anesth Analg 1986; 65: 938-42.
  2. Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, et al. An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician 2013; 16(2 Suppl): S49-283.
  3. Diwan S, Manchikanti L, Benyamin RM, Bryce DA, Geffert S, Hameed H, et al. Effectiveness of cervical epidural injections in the management of chronic neck and upper extremity pain. Pain Physician 2012; 15: E405-34.
  4. Manchikanti L, Boswell MV, Singh V, Benyamin RM, Fellows B, Abdi S, et al. Comprehensive evidence-based guidelines for interventional techniques in the management of chronic spinal pain. Pain Physician 2009; 12: 699-802.
  5. Benzon HT. The long journey of epidural steroid injections. Reg Anesth Pain Med 2013; 38: 171-2.
  6. Manchikanti L. Role of neuraxial steroids in interventional pain management. Pain Physician 2002; 5: 182-99.
  7. Huston CW. Cervical epidural steroid injections in the management of cervical radiculitis: interlaminar versus transforaminal. A review. Curr Rev Musculoskelet Med 2009; 2: 30-42. https://doi.org/10.1007/s12178-008-9041-4
  8. Stout A. Epidural steroid injections for cervical radiculopathy. Phys Med Rehabil Clin N Am 2011; 22: 149-59. https://doi.org/10.1016/j.pmr.2010.10.007
  9. Benyamin RM, Singh V, Parr AT, Conn A, Diwan S, Abdi S. Systematic review of the effectiveness of cervical epidurals in the management of chronic neck pain. Pain Physician 2009; 12: 137-57.
  10. Cohen SP, Bicket MC, Jamison D, Wilkinson I, Rathmell JP. Epidural steroids: a comprehensive, evidence-based review. Reg Anesth Pain Med 2013; 38: 175-200. https://doi.org/10.1097/AAP.0b013e31828ea086
  11. Ferrante FM, Wilson SP, Iacobo C, Orav EJ, Rocco AG, Lipson S. Clinical classification as a predictor of therapeutic outcome after cervical epidural steroid injection. Spine (Phila Pa 1976) 1993; 18: 730-6. https://doi.org/10.1097/00007632-199305000-00010
  12. Stav A, Ovadia L, Sternberg A, Kaadan M, Weksler N. Cervical epidural steroid injection for cervicobrachialgia. Acta Anaesthesiol Scand 1993; 37: 562-6. https://doi.org/10.1111/j.1399-6576.1993.tb03765.x
  13. Catchlove RF, Braha R. The use of cervical epidural nerve blocks in the management of chronic head and neck pain. Can Anaesth Soc J 1984; 31: 188-91. https://doi.org/10.1007/BF03015258
  14. Saal JS, Saal JA, Yurth EF. Nonoperative management of herniated cervical intervertebral disc with radiculopathy. Spine (Phila Pa 1976) 1996; 21: 1877-83. https://doi.org/10.1097/00007632-199608150-00008
  15. Lee SH, Kim KT, Kim DH, Lee BJ, Son ES, Kwack YH. Clinical outcomes of cervical radiculopathy following epidural steroid injection: a prospective study with follow-up for more than 2 years. Spine (Phila Pa 1976) 2012; 37: 1041-7. https://doi.org/10.1097/BRS.0b013e31823b4d1f
  16. Kwon JW, Lee JW, Kim SH, Choi JY, Yeom JS, Kim HJ, et al. Cervical interlaminar epidural steroid injection for neck pain and cervical radiculopathy: effect and prognostic factors. Skeletal Radiol 2007; 36: 431-6. https://doi.org/10.1007/s00256-006-0258-2
  17. Shakir A, Ma V, Mehta B. Prediction of therapeutic response to cervical epidural steroid injection according to distribution of radicular pain. Am J Phys Med Rehabil 2011; 90: 917-22. https://doi.org/10.1097/PHM.0b013e31822de95b
  18. Fish DE, Kobayashi HW, Chang TL, Pham Q. MRI prediction of therapeutic response to epidural steroid injection in patients with cervical radiculopathy. Am J Phys Med Rehabil 2009; 88: 239-46. https://doi.org/10.1097/PHM.0b013e3181951890
  19. Annaswamy TM, Bierner SM, Avraham R. Role of electrodiagnosis in patients being considered for epidural steroid injections. PM R 2013; 5(5 Suppl): S96-9. https://doi.org/10.1016/j.pmrj.2013.03.013
  20. Ackerman WE 3rd, Zhang JM. Serum hs-CRP as a useful marker for predicting the efficacy of lumbar epidural steroid injections on pain relief in patients with lumbar disc herniations. J Ky Med Assoc 2006; 104: 295-9.
  21. Borghouts JA, Koes BW, Bouter LM. The clinical course and prognostic factors of non-specific neck pain: a systematic review. Pain 1998; 77: 1-13. https://doi.org/10.1016/S0304-3959(98)00058-X
  22. Manchikanti L, Cash KA, Pampati V, Malla Y. Two-year follow-up results of fluoroscopic cervical epidural injections in chronic axial or discogenic neck pain: a randomized, double-blind, controlled trial. Int J Med Sci 2014; 11: 309-20. https://doi.org/10.7150/ijms.8069
  23. Kim KT, Song CW. Radiologic finding of patients with neck pain. J Korean Pain Soc 1996; 9: 102-4.
  24. Park CH, Lee SH. Investigation of high-sensitivity C-reactive protein and erythrocyte sedimentation rate in low back pain patients. Korean J Pain 2010; 23: 147-50. https://doi.org/10.3344/kjp.2010.23.2.147
  25. Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, et al. Interventional management of neuropathic pain: NeuPSIG recommendations. Pain 2013; 154: 2249-61. https://doi.org/10.1016/j.pain.2013.06.004
  26. Kang H, Shin HY. Epidural steroid injection in spinal pain: a study on the NECA report. Anesth Pain Med 2014; 9: 9-18.

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