Journal of the Korean Data and Information Science Society

The Korean Data and Information Science Society (한국데이터정보과학회)
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Estimation of the joint conditional distribution for repeatedly measured bivariate cholesterol data using nonparametric copula

비모수적 코플라를 이용한 반복측정 이변량 자료의 조건부 결합 분포 추정

  • Received : 2016.04.15
  • Accepted : 2016.05.19
  • Published : 2016.05.31
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Abstract

We study estimation and inference of the joint conditional distributions of bivariate longitudinal outcomes using regression models and copulas. For the estimation of marginal models we consider a class of time-varying transformation models and combine the two marginal models using nonparametric empirical copulas. Regression parameters in the transformation model can be obtained as the solution of estimating equations and our models and estimation method can be applied in many situations where the conditional mean-based models are not good enough. Nonparametric copulas combined with time-varying transformation models may allow quite flexible modeling for the joint conditional distributions for bivariate longitudinal data. We apply our method to an epidemiological study of repeatedly measured bivariate cholesterol data.

본 논문에서는 이변량 경시적 자료의 조건부 결합 분포를 추정하기 위하여 회귀 모형과 코플라 모형을 연구하였다. 주변 분포의 추정을 위하여 시변 전환 모형을 고려하였고, 이변량 반응변수 각각에 대한 주변 분포를 경험 분포를 이용한 비모수적 코플라를 이용하여 결합하여 조건부 결합 분포를 추정하였다. 주변 분포 모형의 모수 추정치는 추정방정식의 해로 얻어낼 수 있으며 우리가 제안한 모형은 조건부 평균 모형만으로 자료를 설명하기 어려운 경우에 적용될 수 있다. 시변 전환 모형과 비모수적 코플라 모형을 결합한 본 논문의 방법은 반복 측정된 이변량 경시적 자료에 대한 모형화가 모형에 대한 가정에서 비교적 자유로운 장점이 있다. 우리는 본 논문의 방법을 반복 측정된 이변량 콜레스테롤 자료를 분석하는데 적용하여 보았다.

Keywords

References

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