Asian Pacific Journal of Cancer Prevention

  • 제17권8호
  • /
  • Pages.3817-3822
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  • 2016
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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DOI QR코드

DOI QR Code

Clinicopathological Characteristics of Iranian Patients with Lung Cancer: a Single Institute Experience

  • Adnan, Khosravi (Medical Oncology, Tobacco Prevention and Control Research Center, Shahid Beheshti University of Medical Sciences) ;
  • Zahra, Esfahani-Monfared (Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences) ;
  • Sharareh, Seifi (Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences) ;
  • Shirin, Karimi (Pathology, Mycobacteriology Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences) ;
  • Habib, Emami (Tobacco Prevention and Control Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences) ;
  • Kian, Khodadad (Internal Medicine, Dalhousie University, Cape Breton Cancer Centre)
  • 발행 : 2016.08.01
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Lung cancer has long been a leading cause of cancer related death in both women and men worldwide. The focus of this study was to review clinicopathological features of Iranian patients diagnosed with lung cancer. Materials and Methods: Clinicopathological data of 1353 primary lung cancer patients diagnosed during 17 years (1997-2014) in the "National Institute of Tuberculosis and Lung Disease" (NRITLD), Tehran, Iran, were retrospectively reviewed. Results: The median age of patients was 60 (mean: 58.95 years, range: 16-99) and adenocarcinoma was the most prevalent pathology (45.2%). Male/female ratio was 3.22 and 57.2% of patients were smokers (men 70.3%, women 15%). The majority (85.3%) were referred in advanced stages (stage IIIB and IV). Conclusions: Although some of our findings are in concordance with other studies in lung cancer but there are some discrepancies particularly in terms of smoking status and median age of Iranian patients. Further clinical and epidemiological studies are warranted to elucidate etiologic and factors other than smoking contributing to development of lung cancer such as environmental exposures or genetic predisposition.

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참고문헌

  1. Ahmadi J, Khalili H, Jooybar R, et al (2001). Prevalence of cigarette smoking in Iran. Psychol Rep, 89, 339-41. https://doi.org/10.2466/pr0.2001.89.2.339
  2. Almasi Z, Salehiniya H, Amoori N, et al (2016). Epidemiology characteristics and trends of lung cancer incidence in Iran. Asian Pac J Cancer Prev, 17, 557-62. https://doi.org/10.7314/APJCP.2016.17.2.557
  3. AL-Hashimi MMY, Wang XJ (2014). Trend analysis of lung cancer incidence rates in ninawa province, iraq, from 2000 to 2010 - decrease and recent stability. Asian Pac J Cancer Prev, 15, 385-90. https://doi.org/10.7314/APJCP.2014.15.1.385
  4. American Cancer Society. Cancer Facts & Figures 2015(2015). Atlanta: American Cancer Society; 2015.
  5. Australian Institute of Health and Welfare and Cancer Australia. (2011). Lung cancer in Australia: an overview. Cancer series no. 64. Cat. no. CAN 58. Canberra: AIHW.
  6. Baldini E, Strauss, GM (1997). Women and lung cancer: waiting to exhale. Chest, 112, 229-34. https://doi.org/10.1378/chest.112.1.229
  7. Burns D.M, Anderson C.M, Gray N (2011). Do changes in cigarette design influence the rise in adenocarcinoma of the lung? Cancer Causes Control, 22, 13-22. https://doi.org/10.1007/s10552-010-9660-0
  8. Castro CY, Ostrowski ML, Barrios R, et al (2001). Relationship between Epstein-Barr virus and lymphoepithelioma-like carcinoma of the lung a clinicopathologic study of 6 cases and review of the literature. Hum Pathol, 32, 863-72. https://doi.org/10.1053/hupa.2001.26457
  9. Chang JS, Wrensch MR, Hansen HM, et al (2009). Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans. Carcinogenesis, 30,78-87. https://doi.org/10.1093/carcin/bgn261
  10. Chen K-Y, Hsiao C-F, Chang G-C, et al (2015). Estrogen receptor gene polymorphisms and lung adenocarcinoma risk in neversmoking women. J Thorac Oncol, 10, 1413-20. https://doi.org/10.1097/JTO.0000000000000646
  11. Couraud S, Zalcman G, Milleron B, et al (2012). Lung cancer in never smokers - A review. Eur J Cancer, 48, 1299-311. https://doi.org/10.1016/j.ejca.2012.03.007
  12. Dela Cruz CS, Tanoue LT, Matthay RA (2011). Lung cancer: epidemiology, etiology, and prevention. Clin Chest Med, 32, 605-44. https://doi.org/10.1016/j.ccm.2011.09.001
  13. Dey A, Biswas D, Saha SK, et al (2012). Comparison study of clinicoradiological profile of primary lung cancer cases: An Eastern India experience. Indian J Cancer, 49, 89-95. https://doi.org/10.4103/0019-509X.98930
  14. Ei-Basmy A (2013). Profile of lung cancer in Kuwait. Asian Pac J Canccer Prev, 14, 6181-4. https://doi.org/10.7314/APJCP.2013.14.10.6181
  15. Ferlay J, Soerjomataram I, Dikshit R, et al (2012). Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer, 136, 359-86.
  16. Freudenheim JL, Rits J, Smith-Worner S (2005). Alcohol consumption and risk of lung cancer: a pooled analysis of cohort studies. Am J Clin Nutr, 82, 657-67. https://doi.org/10.1093/ajcn/82.3.657
  17. Fontham ET, Correa P, Reynolds P, et al (1994). Environmental tobacco smoke and lung cancer in non-smoking women. A multicenter study. JAMA, 271, 1752-9. https://doi.org/10.1001/jama.1994.03510460044031
  18. Garcia M, Jemal A, Ward EM, et al (2007). Global cancer facts & figures 2007.Atlanta, GA: American Cancer Society 2007.
  19. Gilliland FD, Hunt WC, Archer VE, et al (2000). Radon progeny exposure and lung cancer risk among non-smoking uranium miners. Health Phys, 79, 365-72. https://doi.org/10.1097/00004032-200010000-00004
  20. Goldstraw P, Crowley J, Chansky K, et al (2007). The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groups in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol, 2, 706-14. https://doi.org/10.1097/JTO.0b013e31812f3c1a
  21. Gonlugur U, Gonlugur TE, Kaptanoglu M, et al (2008). The changing epidemiological trends for carcinoma of the lung in Turkey. Saudi Med J, 29, 749-53.
  22. Greene FL, Page DL, Fleming ID, et al (2002). AJCC Cancer Staging Manual 6th ed. Chicago: Springer-Verlag.
  23. Hajmanoochehri F, Mohammadi N, Zohal MA, et al (2014). Epidemiology and clinicopathological characteristics of lung cancer in a teaching hospital in Iran. Asian Pac J Canccer Prev, 15, 2495-500. https://doi.org/10.7314/APJCP.2014.15.6.2495
  24. Hamid MS, Shameem R, Gafoor K, et al (2015). Non-small-cell lung cancer clinicopathologic features and survival outcomes in asian pacific islanders residing in the United States: A SEER Analysis. J Cancer Epidemiol, 2015, 269304??
  25. Higgins K.A, Park D, Lee G.Y, et al (2014). Exercise-induced lung cancer regression: Mechanistic findings from a mouse model. Cancer, 120, 3302-10. https://doi.org/10.1002/cncr.28878
  26. Hoek G, Raaschou-Nielsen O (2014). Impact of fine particles in ambient air on lung cancer. Chin J Cancer, 33, 197-203.
  27. Hosseini M, Naghan PA, Karimi S, et al (2009). Environmental risk factors for lung cancer in Iran: a case-control study. Int J Epidemiol, 38, 989-96. https://doi.org/10.1093/ije/dyp218
  28. Houston KA, Henley SJ, Li J, et al (2014). Patterns in lung cancer incidence rates and trends by histologic type in the United States, 2004-2009. Lung Cancer, 86, 22-8. https://doi.org/10.1016/j.lungcan.2014.08.001
  29. Howlader N, Noone AM, Krapcho M, et al (eds) (2014). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/ csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014
  30. Iran. Encyclopædia Britannica. Encyclopædia Britannica (2012). Retrieved 8 August 2012.
  31. Kanematsu T, Hanibuchi M, Tomimoto H, et al (2010) . Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of Japan. J Med Investigation, 57, 327-33.
  32. Koo LC, Ho JH-C (1990). World wide epidemiological patterns of lung cancer in non-smokers. Int J Epidemiol, 19, 14-2. https://doi.org/10.1093/ije/19.Supplement_1.S14
  33. Lam WK (2005). Lung cancer in Asian women-the environment and genes. Respirol, 4, 408-17.
  34. Lam W. K, White N. W, Chan-Yeung M. M( 2004). Lung cancer epidemiology and risk factors in Asia and Africa. int j tuberc lung, 8, 1045-57.
  35. Lan Q, Hsiung CA, Matsuo K, et al (2012). Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet, 44, 1330-5. https://doi.org/10.1038/ng.2456
  36. Lortet-Tieulenta J, Soerjomatarama I, Ferlaya J, et al (2014). International trends in lung cancer incidence by histological subtype: Adenocarcinoma stabilizing in men but still increasing in women. Lung Cancer, 84, 13-22. https://doi.org/10.1016/j.lungcan.2014.01.009
  37. Malhotra J, Sartori S, Brennan P, et al (2015). Effect of occupational exposures on lung cancer susceptibility: a study of gene-environment interaction analysis. Cancer Epidemiol Biomarkers Prev, 24, 570-9. https://doi.org/10.1158/1055-9965.EPI-14-1143-T
  38. Matakidou A, Eisen T, HoulstonBritish RS (2005). Systematic review of the relationship between family history and lung cancer risk. J Cancer, 93, 825-33. https://doi.org/10.1038/sj.bjc.6602769
  39. Mehrabani D, Tabei SZ, Heydari ST, et al (2008) . Cancer occurrence in Fars Province, Southern Iran. Iranian Red Crescent Med J, 10, 314-22.
  40. Minami, H, Yoshimura, M, Tsubota, N, et al (2000). Lung cancer in women: sex-associated differences in survival of patients undergoing resection for lung cancer. Chest, 118, 1603-9. https://doi.org/10.1378/chest.118.6.1603
  41. Mirtcheva RM, Vazquez M, Yankelevitz DF, et al (2002). Bronchioloalveolar carcinoma and adenocarcinoma with bronchioloalveolar features presenting as ground-glass opacities on CT. Clin Imaging, 26, 95-100. https://doi.org/10.1016/S0899-7071(01)00372-2
  42. Mosavi-Jarrahi A, Gouya MM, Ramazani R, et al (2009). Cancer incidence and mortality in Iran. Ann Oncol, 20, 556-63.
  43. Nakamura H, Saji H (2013). A worldwide trend of increasing primary adenocarcinoma of the lung. Surg Today. [Epub ahead of print]
  44. Navaneelan T, Janz T (2011). Cancer in canada: focus on lung, colorectal, breast and prostate. Statistics Canada Catalogue no. 82-624 - X
  45. Noronha V, Dikshit R, Raut N, et al (2012). Epidemiology of lung cancer in India: Focus on the differences between nonsmokers and smokers: A single-center experience. Indian J Cancer, 49, 74-81. https://doi.org/10.4103/0019-509X.98925
  46. Oken MM, Creech RH, Tormey DC, et al (1982). Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol, 5, 649-55. https://doi.org/10.1097/00000421-198212000-00014
  47. Osawa K, Nakarai C, Uchino K, et al (2012). XRCC3 Gene polymorphism is associated with survival in japanese lung cancer patients. Int J Mol Sci, 13, 16658-67. https://doi.org/10.3390/ijms131216658
  48. Ou SH, Ziogas A, Zell JA-J (2009). Asian ethnicity is a favorable prognostic factor for overall survival in non-small cell lung cancer (NSCLC) and is independent of smoking status. Thorac Oncol, 4, 1083-93. https://doi.org/10.1097/JTO.0b013e3181b27b15
  49. Peres J (2013). No clear link between passive smoking and lung cancer. J Natl Cancer Inst, 105, 1844-6. https://doi.org/10.1093/jnci/djt365
  50. Perrot M, Licker M, Spiliopoulous A, et al (2000). Sex differences in presentation, management and prognosis of patients with non-small cell lung carcinoma. J Thorac Cardiovasc Surg, 119, 21-6. https://doi.org/10.1016/S0022-5223(00)70213-3
  51. Radzikowska E, Glaz P, Roszkowski K (2002). Lung cancer in women: age, smoking, histology, performance status, stage, initial treatment and survival. Population-based study of 20 561 cases. Ann Oncol, 13, 1087-93. https://doi.org/10.1093/annonc/mdf187
  52. Rezazadeh A, Laber DA, Ghim SJ, et al (2009). The role of human papilloma virus in lung cancer: a review of the evidence. Am J Med Sci, 338, 64-7. https://doi.org/10.1097/MAJ.0b013e3181a393ba
  53. Ruano-Ravina A, Figueiras A, Feire-Garbal-M, et al (2006). Antioxidant vitamins and risk of lung cancer. Curr Pharm Des, 12, 599-613. https://doi.org/10.2174/138161206775474396
  54. Sadraei NH, Taghi Riahi (2013) . Idiopathic pulmonary fibrosis in a referral center in Iran: Are patients developing the disease at a younger age? Arch Iranian Med, 16, 177-81.
  55. Salim E.I, Jazieh A.R, Moore M.A (2011). Lung cancer incidence in the Arab League countries: risk factors and control. Asian Pac J Cancer Prev, 12, 17-34.
  56. Santos-Martines MJ, Curull V, Blanco ML, et al (2005). Lung cancer at a university hospital: epidemiological and histological characteristics of a recent and a historical series. Arch Bronconeumo, l41, 307-12.
  57. Sasco A.J, Secretan M.B, Straif K (2004). Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer, 45, 3-9.
  58. Shriver SP, Bourdeau HA, Gubish CT, et al (2000). Sex-specific expression of gastrin realizing peptide receptor: relationship to smoking history and risk of cancer. J Natl Cancer Inst, 92, 24-33. https://doi.org/10.1093/jnci/92.1.24
  59. Siegel RL, Naishadham D, Jemal A (2013). Cancer statistics, 2013. CA Cancer, 63, 11-30. https://doi.org/10.3322/caac.21166
  60. Siegel RL, Miller KD, Jemal A (2015). Cancer statistics, 2015. CA Cancer J, 65, 5-29. https://doi.org/10.3322/caac.21254
  61. Surveillance Epidemiology and End Results (2012). SEER stat fact sheets: lung and bronchus. National Cancer Institute. Bethesda, MD. http://seer.cancer.gov/statfacts/html/lungb.html. Accessed March 22, 2012.
  62. Tarrahi MJ, Mehrabani D, Khademolhosseini F, et al (2009). Lung cancer occurrence in Southern Iran. J Res Med Sci, 14, 139-40.
  63. The World Health Organization histological typing of lung tumours. Second edition (1982). Am J Clin Pathol, 77, 123-36. https://doi.org/10.1093/ajcp/77.2.123
  64. Thomas L, Doyle LA, Edelman MJ (2005). Lung cancer in women: emerging differences in epidemiology, biology, and therapy. Chest, 128, 370-81. https://doi.org/10.1378/chest.128.1.370
  65. Thompson CA, Waldhur T, Schernhammer ES, et al (2012). Smoking and lung cancer: current trends in Austria. M.Wien Klin Wochenschr, 124, 493-9. https://doi.org/10.1007/s00508-012-0207-0
  66. Wang T, Zhou B, Shi J (1996). Lung cancer in non-smoking Chinese women: a case-control study. Lung Cancer, 14, 93-5. https://doi.org/10.1016/S0169-5002(96)90214-7
  67. Wender R, Fontham ET, Barrera E, et al (2013). American cancer society lung cancer screening guidelines. Ca Cancer J Clin, 63, 106-17. https://doi.org/10.3322/caac.21172
  68. Yu YH, Liao CC, Hsu WH, et al (2011). Increased lung cancer risk among patients with pulmonary tuberculosis: a population cohort study. J Thorac Oncol, 6, 32-7. https://doi.org/10.1097/JTO.0b013e3181fb4fcc
  69. Yunesian M, Homayoun-Vash J, Asghari F, et al (2008). Smoking-related respiratory symptoms in Tehran: a crosssectional study. Arch Iran Med, 11, 507-14.