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Gleason's Grading of Prostatic Adenocarcinoma: Inter-Observer Variation Among Seven Pathologists at a Tertiary Care Center in Oman

  • Qureshi, Asim (Pathology Department, Sultan Qaboos University Hospital) ;
  • Lakhtakia, Ritu (Pathology Department, Sultan Qaboos University Hospital) ;
  • Bahri, Maiya AL (Pathology Department, Sultan Qaboos University Hospital) ;
  • Haddabi, Ibrahim Al (Pathology Department, Sultan Qaboos University Hospital) ;
  • Saparamadu, Anna (Pathology Department, Sultan Qaboos University Hospital) ;
  • Shalaby, Asem (Pathology Department, Sultan Qaboos University Hospital) ;
  • Riyami, Marwa Al (Pathology Department, Sultan Qaboos University Hospital) ;
  • Rizvi, Gauhar (Pathology Department, Sultan Qaboos University Hospital)
  • 발행 : 2016.11.01

초록

Prostatic adenocarcinoma is the commonest solid malignancy seen in Omani elderly males 60-80 years of age. The Gleason grade is the most widely used grading system for prostatic carcinoma and is recommended by the World Health Organization. A peer review was carried out at the Pathology Department of Sultan Qaboos University Hospital (SQUH), Oman, to assess the quality of reporting at the center. The aim of this study was to determine inter-observer variation among 7 pathologists working at a tertiary care center in Oman. A total of 47 consecutive prostatic biopsies were interdependently reviewed by seven pathologists and the results obtained were compared with each other and the original diagnosis. This peer review indicated a fair inter-observer agreement (0.482) among 7 pathologists in the department, with fair to moderate agreement when the results were compared to the reported diagnosis, comparable to the published literature. Dual and sub-specialty reporting are being instituted to improve the performance in this vital aspect of pathology.

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참고문헌

  1. Abdollahi A, Meysamie A, Sheikhbahaei S, et al (2012). Inter/intra- bserver reproducibility of Gleason scoring in prostate adenocarcinoma in Iranian pathologists. Urol J, 9, 486-90.
  2. Allsbrook-WC JR, Mangold KA, Johnson MH, et al (2001). Interobserver reproducibility of Gleason grading of prostatic carcinoma: urologic pathologists. Hum Pathol, 32, 74-80. https://doi.org/10.1053/hupa.2001.21134
  3. Epstein JI, Allsbrook WC Jr, Amin MB, et al (2005). The 2005 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma. Am J Surg Pathol, 29, 1228-42. https://doi.org/10.1097/01.pas.0000173646.99337.b1
  4. Gender wise cancer incidence in Oman. Ministry of Health document (2011). www.moh.gov.om.
  5. Gleason DF, Mellinger GT (1974). Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol, 167, 953-8.
  6. Gofrit ON, Zorn KC, Steinberg GD, et al (2008). The will rogers phenomenon in urological oncology. J Urol, 179, 28-33.
  7. Oyama T, Allsbrook-WC JR, Kurokawa K, et al (2005). A comparison of interobserver reproducibility of Gleason grading of prostatic carcinoma in Japan and the United States . Arch Pathol Lab Med, 129, 1004-10.
  8. Singh RV, Agashe SR, Gosavi AV, Sulhyan KR (2011). Interobserver reproducibility of Gleason grading of prostatic adenocarcinoma among general pathologists. Indian J Cancer, 48, 488-95. https://doi.org/10.4103/0019-509X.92277