Asian Pacific Journal of Cancer Prevention

  • 제17권4호
  • /
  • Pages.2343-2344
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  • 2016
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Outcome of Inversion 16 in TKD Positive and Negative Acute Myeloid Leukemia Patients

  • Shahab, Sadaf (Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences) ;
  • Zahid, Danish (Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences) ;
  • Ahmed, Shariq (Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences) ;
  • Nadeem, Muhammad (Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences) ;
  • Farzana, Tasneem (Department of Hematology, NIBD Postgraduate Institute of Life Sciences) ;
  • Taj, Mehwesh (Department of Hematology, NIBD Postgraduate Institute of Life Sciences) ;
  • Ahmed, Nuzhat (Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences) ;
  • Shamsi, Tahir S (Department of Hematology, NIBD Postgraduate Institute of Life Sciences)
  • 발행 : 2016.06.01
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  1. Abu-Duhier FM, Goodeve AC, Wilson GA, et al (2001). identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia. Br J Haematol, 113, 983-8. https://doi.org/10.1046/j.1365-2141.2001.02850.x
  2. Ahmad F, Mohota R, Sanap S, Mandava S, Das BR (2014). Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype indian acute myeloid leukemia patients. Asian Pac J Cancer Prev, 15, 1247-53. https://doi.org/10.7314/APJCP.2014.15.3.1247
  3. Frohling S, Schlenk RF, Breitruck J, et al ( 2002). Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm. Blood, 100, 4372-80. https://doi.org/10.1182/blood-2002-05-1440
  4. Ishfaq M, Malik A, Faiz M, et al (2012). Molecular characterization of FLT3 mutations in acute leukemia patients. Asian Pac J Cancer Prev, 13, 4581-5. https://doi.org/10.7314/APJCP.2012.13.9.4581
  5. Janke H, Pastore F, Schumacher D, et al (2014). Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia. PLoS ONE, 9, 89560 https://doi.org/10.1371/journal.pone.0089560
  6. Kottaridis PD, Gale RE, Frew ME, et al (2001). The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood, 98, 1752-9. https://doi.org/10.1182/blood.V98.6.1752
  7. Mead A J, Linch DC, Hills RK (2007). FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia, Blood, 110, 1262-70 https://doi.org/10.1182/blood-2006-04-015826
  8. Mukda E, Pintaraks K, Sawangpanich R, Wiangnon S, Pakakasama S (2011). FLT3 and NPM1 gene mutations in childhood acute myeloblastic leukemia. Asian Pac J Cancer Prev, 12, 1827-31
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  10. Renneville A, Abdelali RB, Chevret S, et al (2014). Clinical impact of gene mutations and lesions detected by SNParray karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial. Oncotarget, 5, 916-32. https://doi.org/10.18632/oncotarget.1536
  11. Shahab S, Shamsi T, Ahmed N (2012). Molecular involvement and prognostic importance of Fms-like tyrosine kinase 3 in acute myeloid leukemia. Asian Pac J Cancer Prev, 13, 4203-08 https://doi.org/10.7314/APJCP.2012.13.8.4203
  12. Su L, Gao SJ, Tan YH, Han W, Li W (2013). Associations between age, cytogenetics, FLT3-ITD, and marrow leukemia cells identified by flow cytometry. Asian Pac J Cancer Prev, 14, 5341-44 https://doi.org/10.7314/APJCP.2013.14.9.5341
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