The Journal of Korean Institute of Communications and Information Sciences (한국통신학회논문지)

The Korean Institute of Commucations and Information Sciences (한국통신학회)
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Experiment of Response with Voltage for Stem Cell Regeneration Treatment

줄기세포재생 치료를 위한 배지의 전압 반응 실험

  • Yoon, Ki-Cheol (Korea Advanced Institute of Science and Technology, The Cho Chun Skik Graduate School for Green Transportation) ;
  • Kim, Jung-Tae (Kwanwoon Univerisity, Dept. of Radio Science and Engineering) ;
  • Kim, Beom-Su (Bonecell Biotech Inc. R&D Center) ;
  • Lee, Jun (Wonkwang Bone Regeneration Research Instiute) ;
  • Lee, Jong-Chul (Kwanwoon Univerisity, Dept. of Electronics Convergence Engineering)
  • Received : 2016.04.14
  • Accepted : 2016.07.21
  • Published : 2016.07.31
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Abstract

In this paper, the electrical values of resistance, current, and voltage condition of reactivity is analyzed by applying the direct current (DC) voltage in medium for stem cell regeneration treatment. The voltage response by medium is related to electrical stimulation in the process of induction of differentiation for stem cell and the differentiation condition can be checked depending on the response of voltage condition. If the voltage level is lower in reacting response of a medium, the stem cell stimulation condition is stable, and if the voltage changing level is higher, the stem cell stimulation condition is unstable and a considerable loss will be resulted in the differentiation process. In this research, the optimization of electrical stimulation condition is expected for possible stem cell regeneration treatment.

본 논문은 줄기세포 재생 치료를 위해 사용되는 배지에 직류전압을 인가하여 배지에 반응되는 전기적인 저항 값, 전류 값 그리고 전압 값의 상태에 대해 분석하였다. 배지에 반응되는 전압은 줄기세포 분화 유도 과정에서 전기적인 자극에 연관되며 반응 전압 상태에 따라 분화의 상태에 대해 확인 할 수 있다. 배지의 반응 전압에서 전압변화 레벨이 적으면 줄기세포 자극 조건이 안정적이며 만일 전압 변화 레벨이 심하면 줄기세포 자극 조건이 불안정하여 줄기세포 분화 과정에서 상당한 손실을 따르게 될 수 있다. 본 연구는 줄기세포 재생 치료의 가능성을 위해 전기적인 자극 조건의 최적화 하는데 도움이 될 것으로 기대한다.

Keywords

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