DOI QR코드

DOI QR Code

Long-term evaluation of teeth and implants during the periodic maintenance in patients with viral liver disease

  • Yoon, Da-Le (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
  • Kim, Yong-Gun (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
  • Cho, Jin-Hyun (Department of Prosthodontics, School of Dentistry, Kyungpook National University) ;
  • Lee, Sang-Kyu (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University) ;
  • Lee, Jae-Mok (Department of Periodontology, School of Dentistry, Kyungpook National University)
  • Received : 2016.04.14
  • Accepted : 2016.08.08
  • Published : 2016.08.31

Abstract

PURPOSE. This study was designed to investigate the maintenance of teeth and implants in patients with viral liver disease. MATERIALS AND METHODS. 316 patients without any significant systemic disease were selected as a control group. Liver disease group was consisted of 230 patients. Necessary data were collected using clinical records and panoramic radiographs. Then, the patients were subdivided into 2 groups based on the type of active dental therapy received before maintenance period (Pre-Tx). Analysis for finding statistically significant difference was performed based on the need for re-treatment of active dental therapy (Re-Tx) and change in the number of teeth (N-teeth) and implants (N-implants). RESULTS. Comparing to control group, the patients with liver disease showed higher value on N-teeth, N-implants, and Re-Tx. Statistically significant differences were found on N-teeth (P=.000) and Re-Tx (P=.000) in patients with non-surgical Pre-Tx. Analysis based on severity of liver disease showed that N-teeth and Re-Tx were directly related to severity of liver disease regardless of received type of Pre-Tx. Significant differences were found on N-teeth (P=.003) and Re-Tx (P=.044) in patients with non-surgical Pre-Tx. CONCLUSION. In this study, it was concluded that liver disease might influence the loss of teeth and cause the relapse of dental disease during maintenance period in patients. A significant positive relationship between tooth and implant loss and severity of liver disease seems to exist.

Keywords

References

  1. Newman MG, Takei HT, Klokkevold PR, Carranza FA. Carranza's clinical periodontology. 10th ed. St. Louis; Saunder Elsevier; 2006.
  2. Grau-Garcia-Moreno DM. Dental management of patients with liver disease. Med Oral 2003;8:231.
  3. Demas PN, McClain JR. Hepatitis: implications for dental care. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:2-4. https://doi.org/10.1016/S1079-2104(99)70184-8
  4. Wisnom C, Siegel MA. Advances in the diagnosis and management of human viral hepatitis. Dent Clin North Am 2003;47:431-47. https://doi.org/10.1016/S0011-8532(03)00021-1
  5. Golla K, Epstein JB, Cabay RJ. Liver disease: current perspectives on medical and dental management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:516-21. https://doi.org/10.1016/S1079-2104(04)00643-2
  6. Cruz-Pamplona M, Margaix-Munoz M, Sarrion-Perez MG. Dental considerations in patients with liver disease. J Clin Exp Dent 2011;3:e127-34.
  7. Mahboobi N, Agha-Hosseini F, Mahboobi N, Safari S, Lavanchy D, Alavian SM. Hepatitis B virus infection in dentistry: a forgotten topic. J Viral Hepat 2010;17:307-16. https://doi.org/10.1111/j.1365-2893.2010.01284.x
  8. DePaola LG. Managing the care of patients infected with bloodborne diseases. J Am Dent Assoc 2003;134:350-8. https://doi.org/10.14219/jada.archive.2003.0166
  9. Bagán JV, Alapont L, Sanz C, del Olmo JA, Morcillo E, Cortijo J, Milián MA, Rodrigo JM. Dental and salivary alterations in patients with liver cirrhosis: a study of 100 cases. Med Clin (Barc) 1998;111:125-8.
  10. Novacek G, Plachetzky U, Potzi R, Lentner S, Slavicek R, Gangl A, Ferenci P. Dental and periodontal disease in patients with cirrhosis--role of etiology of liver disease. J Hepatol 1995;22:576-82. https://doi.org/10.1016/0168-8278(95)80453-6
  11. Coates EA, Brennan D, Logan RM, Goss AN, Scopacasa B, Spencer AJ, Gorkic E. Hepatitis C infection and associated oral health problems. Aust Dent J 2000;45:108-14. https://doi.org/10.1111/j.1834-7819.2000.tb00249.x
  12. Guggenheimer J, Eghtesad B, Close JM, Shay C, Fung JJ. Dental health status of liver transplant candidates. Liver Transpl 2007;13:280-6. https://doi.org/10.1002/lt.21038
  13. Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease. Br Dent J 2003;195:439-45. https://doi.org/10.1038/sj.bdj.4810593
  14. Ilguy D, Ilguy M, Dincer S, Bayirli G. Prevalence of the patients with history of hepatitis in a dental facility. Med Oral Patol Oral Cir Bucal 2006;11:E29-32.
  15. Grossmann Sde M, Teixeira R, de Aguiar MC, de Moura MD, do Carmo MA. Oral mucosal conditions in chronic hepatitis C Brazilian patients: a cross-sectional study. J Public Health Dent 2009;69:168-75. https://doi.org/10.1111/j.1752-7325.2009.00119.x
  16. Konig J, Plagmann HC, Ruhling A, Kocher T. Tooth loss and pocket probing depths in compliant periodontally treated patients: a retrospective analysis. J Clin Periodontol 2002;29:1092-100. https://doi.org/10.1034/j.1600-051X.2002.291208.x
  17. Ng MC, Ong MM, Lim LP, Koh CG, Chan YH. Tooth loss in compliant and non-compliant periodontally treated patients: 7 years after active periodontal therapy. J Clin Periodontol 2011;38:499-508. https://doi.org/10.1111/j.1600-051X.2011.01708.x
  18. Radcke S, Dillon JF, Murray AL. A systematic review of the prevalence of mildly abnormal liver function tests and associated health outcomes. Eur J Gastroenterol Hepatol 2015;27:1-7. https://doi.org/10.1097/MEG.0000000000000233
  19. Liu J. Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver. World J Gastroenterol 2014;20:14672-85. https://doi.org/10.3748/wjg.v20.i40.14672
  20. Douglas LR, Douglass JB, Sieck JO, Smith PJ. Oral management of the patient with end-stage liver disease and the liver transplant patient. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86:55-64. https://doi.org/10.1016/S1079-2104(98)90150-0

Cited by

  1. Peri-implant soft tissue status and crestal bone levels around adjacent implants placed in patients with and without type-2 diabetes mellitus: 6 years follow-up results vol.20, pp.4, 2018, https://doi.org/10.1111/cid.12617
  2. Survival of adjacent-dental-implants in prediabetic and systemically healthy subjects at 5-years follow-up pp.15230899, 2019, https://doi.org/10.1111/cid.12715
  3. Bone healing around titanium implants in a preclinical model of bile duct ligation‐induced liver injury vol.32, pp.8, 2021, https://doi.org/10.1111/clr.13792