Environmental Engineering Research

  • 제21권3호
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  • Pages.247-255
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  • 2016
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  • 1226-1025(pISSN)
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  • 2005-968X(eISSN)
대한환경공학회 (Korean Society of Environmental Engineers)
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DOI QR Code

Trace elements analysis in some medicinal plants using graphite furnace-atomic absorption spectroscopy

  • Anal, Jasha Momo H. (Elemental Analysis Section, Sophisticated Analytical Instrument Facility (SAIF), North Eastern Hill University) ;
  • Chase, Petevino (Department of Environmental Studies, North Eastern Hill University)
  • 투고 : 2016.01.13
  • 심사 : 2016.04.08
  • 발행 : 2016.09.30
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초록

Ten trace elements (Mg, Ca, V, Cr, Mn, Fe, Cu, Zn, Mo, and Cd) were determined in seven traditionally used wild medicinal plants of the Nagas in the North-East India viz Cynoglossum furcatum Wallich, Elsholtzia blanda Bentham, Lycopodium cernuum Linnaeus, Potentilla fulgens Wallich ex Hooker, Swertia macrosperma C.B. Clarke, Thalictrum foliolosum DC and Valeriana jatamansi Jones. Plant samples were dried, weighed, digested and analyzed for their mineral distribution level ranging from trace to major elements by graphite furnace-atomic absorption spectroscopy. All the medicinal herbs studied were found to contain the ten elements analyzed. The elemental concentration is given in mg/kg. Mg and Ca are present in high concentrations in both the roots and leaves of the plant samples. Among trace transition metals Fe had the highest concentration, followed by Mn, Cr, Cu, V, Zn, and Mo. Analysis showed that the toxic Cd element was at a lower concentration and is within the permissible limit of FAO/WHO, California standards and United States Pharmacopeia Limit for Nutritional Supplements.

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참고문헌

  1. Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z. Medicinal Plants in Therapy. Bull. WHO. 1985;63:965-981.
  2. Ajasab AMO, Bellob MO, Ibrahimb AO, Ogunwandea IA, Olawore NO. Heavy trace metals and macronutrients status in herbal plants of Nigeria. Food Chem. 2004;85:67-71. https://doi.org/10.1016/j.foodchem.2003.06.004
  3. Shirin K, Imad S, Shafiq S, Fatima K. Determination of major and trace elements in the indigenous medicinal plant Withania somnifera and their possible correlation with therapeutic activity. J. Saudi Chem. Soc. 2010;14:97-100. https://doi.org/10.1016/j.jscs.2009.12.015
  4. Chase P, Singh OP. Ethnomedicinal Plants Used by Angami Tribe of Nagaland, India. Indian J. Trop. Biodiv. 2013;21:29-42.
  5. Welz B, Sperling M. Atomic absorption Spectroscopy Wiley-VCH Verlag Gmbh, Weinheim; 1999. p. 614-647.
  6. Classen HG. Magnesium and potassium deprivation and supplementation in animals and man: aspects in view of intestinal absorption. Magnesium 1984;3:257-264.
  7. Jing M, Aaron RF, Melnick S, et al. Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: the Aric study. J. Clin. Epidemiol. 1995;48:927-940. https://doi.org/10.1016/0895-4356(94)00200-A
  8. WHO/FAO Vitamin and mineral requirements in human nutrition: Report of a joint FAO/WHO expert consultation, World Health Organization and Food and Agriculture Organization of the United Nations; 2004. p. 59-85.
  9. WHO Guidelines: Calcium supplementation in pregnant women. Geneva, World Health Organization; 2013. p. 31.
  10. WHO Vanadium, in Air Quality Guidelines-Second Edition, WHO Regional Office for Europe, Copenhagen, Denmark; 2000.
  11. WHO Trace elements in human nutrition and health: A Report of a re-evaluation of the role of trace elements in human health and nutrition; 1996. p. 155-159.
  12. Raju GJN, Sarita P, Rao JCS, Rao KCB, Reddy SB. Correlation of trace elemental content in selected anticancer medicinal plants with their curative ability using particle induced X-ray emission (PIXE). J. Med. Plants Res. 2013;7:1081-1086.
  13. Vincent JB. Elucidating a biological role for chromium at a molecular level. Acc. Chem. Res. 2000;33:503-510. https://doi.org/10.1021/ar990073r
  14. Erikson KM, Syversen T, Aschner J, Aschner M. Interactions between excessive Manganese-exposure and dietary iron-deficiency in neurodegeneration. Environ. Toxicol. Pharmacol. 2005;19:415-421. https://doi.org/10.1016/j.etap.2004.12.053
  15. Prasad MNV. Trace elements as contaminants and nutrients; Consequences in ecosystems and human health. John Wiley & Sons, Inc. Hoboken, New Jersey; 2008. p. 769.
  16. Aaron BB, Kwakye GF, Hernandez EH, Aschner M. Role of Manganese in neurodegenerative diseases. J. Trace Elem. Med. Biol. 2011;25:191-203. https://doi.org/10.1016/j.jtemb.2011.08.144
  17. De Maeyer E, Adiels-Tegman M, Raystone E. The prevalence of anaemia in the world. World Health Stat. Q. 1985;38: 302-316.
  18. WHO Quality Control Methods for Medicinal non-essential trace elements having functions neither in Plant Materials, Geneva, Revised; 2005.
  19. FAO/WHO human vitamin and mineral requirements, report of a joint FAO/WHO expert consultation Bangkok, Thailand; 2001. p. 281.
  20. Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am. J. Clin. Nutr. 1998;68(suppl.):447S-463S. https://doi.org/10.1093/ajcn/68.2.447S
  21. Krishnamachari KA, Krishnaswamy K. An epidemiological study of the syndrome of genu valgum among residents of endemic areas for fluorosis in Andhra Pradesh. Indian J. Med. Res. 1974;62:1415-1423.
  22. Jasha MHA. Trace and Essential Elements Analysis in Cymbopogon citratus (DC.) Stapf Samples by Graphite Furnace-Atomic Absorption Spectroscopy and Its Health Concern. J Toxicol 2014; Article ID 690758, doi:10.1155/2014/690758.
  23. Bernard A. Cadmium and its adverse effects on human health. Indian J. Med. Res. 2008;128:557-564.
  24. FAO/WHO Expert Committee on Food Additives, Evaluation of Certain Food Additives, Sixty-Third Report of the Joint FAO/WHO Expert Committee on Food Additives, WHO Technical Report Series(JECFA); 2005. p. 928.
  25. Kaim W, Schwederski B, Klein A. Historical background, current relevance and perspectives, In: Bioinorganic chemistry: Inorganic elements in the chemistry of life. 2nd ed. John Wiley & Sons Ltd; 2013. p. 1-7
  26. Morawiec M. Effects of harmful trace elements on iron, zinc and copper: Their interactions in animals and humans. II. Lead. Rocz Panstw Zakl Hig 1991;42:12-16.
  27. Suttle NF. Recent studies of the coppermolybdenum antagonism. Proc. Nutr. Soc. 1974;33:299-305. https://doi.org/10.1079/PNS19740053
  28. Gover RA. Nutrition and metal toxicity. Am. J. Clin. Nutr. 1995;61(suppl.):646S-50S. https://doi.org/10.1093/ajcn/61.3.646S
  29. Tiffin LO. The form and distribution of metals in plants: An overview. In Proc. Handford Life Sciences Symp., U.S. Department of Energy, Symposium Series. Washington DC; 1977. p. 315.
  30. Lama YC, Ghimire SK, Aumeeruddy-Thomas Y. Medicinal Plants of Dolpo: Amchisi Knowledge and Conservation. WWF Nepal Program, Baluwatar, Kathmandu, Nepal, 2001. ISBN: 99933-94-01-7.
  31. Gao YT, Li L, Dai JH, Bei YX, Guo Y. Extraction of flavonoid from Chinese materia medics by ultrasonic extraction coupling with propyl-alcohol ammonium sulfate aqueous two-phase separation and its antioxidation of extractives. Chin. Pharm. J. 2009;44:736-739.
  32. Lai YG, Xu JH, Jiang HD, Zeng S, Zhao Y. HPLC simultaneous determination of three flavonoid aglycones in Elsholtzia blanda Benth. Chin. J. Pharm. Anal. 2006;26:1404-1407.
  33. Ling HY, Lou YJ, Lou HG, Wu HH. Protective effect of total flavones from Elsholtzia blanda (TFEB) on myocardial ischemia induced by coronary occlusion in canines. J. Ethnopharmacol. 2004;94:101-107. https://doi.org/10.1016/j.jep.2004.04.016
  34. Wang FM, Yao TW, Zeng S. Analysis of luteolin in Elsholtzia blanda Benth. by RP-HPLC. Pharmazie 2005;60:648-649.
  35. Zuo GY, Wanga GC, Zhao YB, et al. Screening of Chinese medicinal plants for inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). J. Ethnopharmacol. 2008;120:287-290. https://doi.org/10.1016/j.jep.2008.08.021
  36. Zhang Z, Elsohly HN, Melissa JR, Pasco DS, Walker LA, Clark AM. Natural products inhibiting Candida albicans secreted aspartic proteases from Lycopodium cernuum. J. Nat. Prod. 2002;65:979-985. https://doi.org/10.1021/np0200616
  37. Ndip RN, Ajonglefac AN, Mbullah SM, et al. In vitro anti-Helicobacter pylori activity of Lycopodium cernuum (Linn) Pic. Serm. Afr. J. Biotechnol. 2008;7:3989-3994.
  38. Syiem D, Syngai C, Khup PZ., Khongwir BS, Kharbuli B, Kayang H. Hypoglycemic effects of Potentilla fulgens L. in normal and alloxan-induced diabetic mice. J. Ethnoph. 2002;83:55-61. https://doi.org/10.1016/S0378-8741(02)00190-3
  39. Syiem D, Syngai C, Kharbuli B, Kayang H, Khongwir BS. Anti-tumor activity of crude root extract of Potentilla fulgens. Indian Drugs 2003;40:124-125.
  40. Rosangkima G, Prasad SB. Antitumour activity of some plants from Meghalaya and Mizoram against murine ascites Dalton's Lymphoma. Indian J. Exp. Biol. 2004;42:981-988.
  41. Uprety Y, Asselin H, Boon EK, Yadav S, Shrestha KK. Indigenous use and bio-efficacy of medicinal plants in the Rasuwa District, Central Nepal. J. Ethnobiol. Ethnomed. 2010;6:3. https://doi.org/10.1186/1746-4269-6-3
  42. Hynniewta SR, Kumar Y. Herbal remedies among the Khasi traditional healers and village folks in Meghalaya. Indian J. Tradit. Knowl. 2008;7:581-586.
  43. Negi JS. Evaluation of trace element contents in Swertia macrosperma. Nat. Prod. Res. 2012;26:72-76. https://doi.org/10.1080/14786419.2010.535167
  44. Prakash A, Basumatary PC, Ghosal S, Handa SS. Chemical constituents of Swertia macrosperma. Planta. Medica. 1982;45:61-62. https://doi.org/10.1055/s-2007-971248
  45. Sinha SC. Medicinal plants of Manipur. Manipur Association for science & Society (MASS). Imphal; 1996.
  46. Uniyal SK, Singh KN, Jamwal P, Lal B. Traditional use of medicinal plants among the tribal communities of Chhota Bhangal. Western Himalaya. J. Ethnobiol. Ethnomed. 2006;2:14. https://doi.org/10.1186/1746-4269-2-14
  47. Sharma PK, Lal B. Ethnobotanical notes on some medicinal and aromatic plants of Himachal Pradesh. Indian J. Tradit. Knowl. 2005;4:424-428.
  48. Khare CP. Indian Medicinal Plants: An Illustrated Dictionary. Springer Science, Business Media: LLC; 2007.
  49. Bagchi P, Hopper W. Virtual screening of compounds from valeriana jatamansi with ${\alpha}$-synuclein international conference on bioscience, biochemistry and bioinformatics. IPCBEE 2011;5:11-14.
  50. Thusoo S, Sahil G, Rasleen S, et al. Antioxidant Activity of Essential Oil and Extracts of Valeriana jatamansi Roots. BioMed Research International. 2014; Article ID 614187, 4 pages. doi:10.1155/2014/614187.

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