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Analysis of Risk factors & Morphological Ultrasound Image for Gallbladder Polyp in Adults Living in Busan and Gyeongnam Provinces

부산·경남 지역 성인의 담낭용종 위험인자 및 초음파 영상의 형태학적 분석

  • An, Hyeon (Department of Radiology, Inje University Busan Paik Hospital) ;
  • Hwang, Chul-Hwan (Department of Radiation Oncology, Pusan National University Hospital) ;
  • Ko, Sung-Jin (Department of Radiological Science, College of Health Sciences, Catholic University of Pusan) ;
  • Kim, Chang-Soo (Department of Radiological Science, College of Health Sciences, Catholic University of Pusan)
  • 안현 (인제대학교 부산백병원 영상의학과) ;
  • 황철환 (인제대학교 부산백병원 방사선종양학과) ;
  • 고성진 (부산가톨릭대학교 보건과학대학 방사선학과) ;
  • 김창수 (부산가톨릭대학교 보건과학대학 방사선학과)
  • Received : 2016.08.05
  • Accepted : 2016.08.31
  • Published : 2016.09.30

Abstract

This study were to evaluate risk factors of GB polpy in Busan and Gyeongnam area. This study was performed with patients by abdominal ultrasonography among the patients who came to the P hospital from January to May 2016. Among them, risk factors were analyzed on 399 people at the same time when abdominal ultrasonography and hematological test. The statistical analysis of risk factors related to the GB ployp was performed by independent t-test and chi-square test. In consider of difference verification result for calculations odds ratio about independent variables, multiple logistic regression analysis to conduct verify adequacy by calculating forecasting model from variable. As a result, GB polyp risk factors have relevance to male, HBsAg positive, triglyceride. GB polyp risk factors confirmed to male, HBsAg positive, triglyceride were calculated forecasting model and forecasting probability value. Forecasting probability sensitivity 61.0%, specificity 76.8%, ROC area under curve 0.735 showed, it confirmed validity of forecasting model. When analyzing the GB polyps morphologically, among the GB polyp types observed from abdominal ultrasonography, the hyperechoic and homogeneous pattern with neck was the largest as shown from 27.5% and two GB polyps were shown most from 38%, sizes were shown most by maximum diameter, 5 to 10mm from 53%. As a disease accompany with GB polyp showed mild fatty liver(23%), diffuse hepatopathy(21%).

본 연구는 부산 경남지역에서 담낭용종의 위험인자 및 초음파영상의 형태학적 분포를 알아보고자 하였다. 실험 대상은 2016년 1월~5월까지 부산 P병원 내원환자의 복부초음파 영상을 대상으로 하였다. 그 중 복부초음파와 혈청학적 검사를 동시에 실시한 399명을 대상으로 위험인자를 분석하였다. 담낭용종 위험인자들의 통계분석은 독립표본 t검정(independent t-test)과 카이제곱 검정(chi-square test)을 시행하였다. 차이검정 결과를 고려하여 독립변수에 대한 상대 위험비(odds ratio, OR) 산출을 위해 다중 로지스틱 회귀분석(multiple logistic regression analysis)을 시행하여 변수들로부터 예측모형을 산정하여 타당성을 검정하였다. 그 결과 담낭용종 위험인자로 남성, HBsAg 양성, 중성지방이 관련이 있음을 알 수 있었다. 담낭용종의 위험인자로 확인된 남성, HBsAg 양성, 중성지방으로 예측모형 및 예측 확률값을 산정하였다. 예측확률의 민감도 61.0%, 특이도 76.8%를 보였으며, ROC 곡선의 AUC 결과는 0.735를 보여 예측모형의 타당성을 확인할 수 있었다. 복부 초음파검사 상 관찰되는 담낭용종의 형태학적 분석 결과는 고 에코, 유경, 균질한 형태가 가장 많은 분포(27.5%)를 나타내었으며, 용종 개수는 2개(38%), 크기는 5~10 mm (53%)로 가장 많았다. 담낭용종과 관련된 간질환으로는 mild fatty liver (23%), diffuse hepatopathy (21%)로 나타났다.

Keywords

References

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