Journal of Biosystems Engineering

Korean Society for Agricultural Machinery (한국농업기계학회)
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Iron Oxide Nanoparticle-incorporated Alginate Capsules as Magnetic Field-assisted Potential Delivery Platforms for Agriculture Pesticides and Biocontrol Agents

  • Lee, Dohyeon (Department of Rural and Biosystems Engineering, Chonnam National University) ;
  • Choi, Kyoung Soon (Advanced Nano-Surface Research Group, Korea Basic Science Institute (KBSI)) ;
  • Kim, Daun (Department of Rural and Biosystems Engineering, Chonnam National University) ;
  • Park, Sunho (Department of Rural and Biosystems Engineering, Chonnam National University) ;
  • Kim, Woochan (Department of Rural and Biosystems Engineering, Chonnam National University) ;
  • Jang, Kyoung-Je (Department of Biosystems & Biomaterials Science and Engineering, Seoul National University) ;
  • Lim, Ki-Taek (Department of Biosystems Engineering, Kangwon National University) ;
  • Chung, Jong Hoon (Department of Biosystems & Biomaterials Science and Engineering, Seoul National University) ;
  • Seonwoo, Hoon (Department of Industrial Machinery Engineering, Sunchon National University) ;
  • Kim, Jangho (Department of Rural and Biosystems Engineering, Chonnam National University)
  • Received : 2017.11.08
  • Accepted : 2017.11.27
  • Published : 2017.12.01
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Abstract

Purpose: Biocompatible capsules have recently been highlighted as a novel platform for delivering various components, such as drug, food, and agriculture pesticides, to overcome the current limitations of living systems, such as those in agriculture, biology, the environment, and foods. However, few active targeting systems using biocompatible capsules and physical forces simultaneously have been developed in the agricultural engineering field. Methods: Here, we developed an active targeting delivery platform that uses biocompatible alginate capsules and controls movements by magnetic forces for agricultural and biological engineering applications. We designed and fabricated large-scale biocompatible capsules, using custom-made nozzles ejecting alginate solutions for encapsulation. Results: To develop the active target delivery platforms, we incorporated iron oxide nanoparticles in the large-scale alginate capsules. The sizes of alginate capsules were controlled by regulating the working conditions, such as concentrations of alginate solutions and iron oxide nanoparticles. Conclusions: We confirmed that the iron oxide particle-incorporated large-scale alginate capsules moved actively in response to magnetic fields, which will be a good strategy for active targeted delivery platforms for agriculture and biological engineering applications, such as for the controlled delivery of agriculture pesticides and biocontrol agents.

Keywords

References

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