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Evaluation of the correlation between gross lung score and microscopic diagnosis for swine pneumonia in Korean slaughterhouses

국내 도축돈에서 발생한 폐렴에 대한 실물 폐 병변 지수와 조직병리학적 진단의 상관성 평가

  • Lee, Hong-Seok (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Myung-Chul (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Na-Yon (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Hwang, Sung-Hyun (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Ji, Sumin (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Park, Young Kyung (Department of Veterinary Microbiology, College of Veterinary Medicine, Seoul National University) ;
  • Park, Yong Ho (Department of Veterinary Microbiology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Yongbaek (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University)
  • 이홍석 (서울대학교 수의과대학 임상병리학실) ;
  • 김명철 (서울대학교 수의과대학 임상병리학실) ;
  • 김나연 (서울대학교 수의과대학 임상병리학실) ;
  • 황성현 (서울대학교 수의과대학 임상병리학실) ;
  • 지수민 (서울대학교 수의과대학 임상병리학실) ;
  • 박영경 (서울대학교 수의과대학 수의미생물학실) ;
  • 박용호 (서울대학교 수의과대학 수의미생물학실) ;
  • 김용백 (서울대학교 수의과대학 임상병리학실)
  • Received : 2017.07.01
  • Accepted : 2017.11.01
  • Published : 2017.12.31

Abstract

To reduce swine production costs, a slaughter check system has been developed in countries with an advanced swine industry. Evaluation of lung lesions in carcasses is a critical part of the slaughter check system. This study was performed to collect background information for use in developing a slaughter check system in Korea. Lung tissues and their gross images were collected from slaughterhouses in Gyeonggi-do, Korea. Scoring of the gross lung lesions was performed on the lung images. Histopathologic examination was conducted to classify the pulmonary lesions as bronchopneumonia or interstitial pneumonia. Scores of the gross lung lesions were significantly different between bronchopneumonia and interstitial pneumonia groups (p < 0.001). A 90% confidence interval of gross lung lesion scores was established for the bronchopneumonia group, and the lesion scoring had a sensitivity of 100% and specificity of 77.3%. The gross lung lesion scoring test was subjected to a diagnostic distinction evaluation by examining the receiver operating characteristic curve and was appraised as having good discrimination for bronchopneumonia. Establishment of a gross lung lesion scoring test for the diagnosis of bronchopneumonia could be valuable as a screening test of macroscopic bronchopneumonia in swine slaughter check system.

Keywords

References

  1. Baptista F, Dahl J, Nielsen LR. Factors influencing Salmonella carcass prevalence in Danish pig abattoirs. Prev Vet Med 2010, 95, 231-238. https://doi.org/10.1016/j.prevetmed.2010.04.007
  2. Chae C. A review of porcine circovirus 2-associated syndromes and diseases. Vet J 2005, 169, 326-336. https://doi.org/10.1016/j.tvjl.2004.01.012
  3. Choi YK, Goyal SM, Joo HS. Retrospective analysis of etiologic agents associated with respiratory diseases in pigs. Can Vet J 2003, 44, 735-737.
  4. Christensen J, Ellegaard B, Petersen BK, Willeberg P, Mousing J. Pig health and production surveillance in Denmark: sampling design, data recording, and measures of disease frequency. Prev Vet Med 1994, 20, 47-61. https://doi.org/10.1016/0167-5877(94)90107-4
  5. Davies PR, Bahnson PB, Grass JJ, Marsh WE, Dial GD. Comparison of methods for measurement of enzootic pneumonia lesions in pigs. Am J Vet Res 1995, 56, 9-14.
  6. Feng Z, Shao G, Liu M, Wu X, Zhou Y, Yuan G. Immune responses to the attenuated Mycoplasma hyopneumoniae 168 strain vaccine by intrapulmonic immunization in piglets. Agric Sci China 2010, 9, 423-431. https://doi.org/10.1016/S1671-2927(09)60113-9
  7. Gardner IA, Willeberg P, Mousing J. Empirical and theoretical evidence for herd size as a risk factor for swine diseases. Anim Health Res Rev 2002, 3, 43-55. https://doi.org/10.1079/AHRR200239
  8. Hansen MS, Pors SE, Jensen HE, Bille-Hansen V, Bisgaard M, Flachs EM, Nielsen OL. An investigation of the pathology and pathogens associated with porcine respiratory disease complex in Denmark. J Comp Pathol 2010, 143, 120-131. https://doi.org/10.1016/j.jcpa.2010.01.012
  9. Harms PA, Halbur PG, Sorden SD. Three cases of porcine respiratory disease complex associated with porcine circovirus type 2 infection. J Swine Health Prod 2002, 10, 27-30.
  10. Hosmer DW Jr, Lemeshow S, Sturdivant RX. Applied Logistic Regression. 3rd ed. pp. 177, Wiley, Hoboken, 2013.
  11. Huhn RG. Swine enzootic pneumonia: incidence and effect on rate of body weight gain. Am J Vet Res 1970, 31, 1097-1108.
  12. Hurnik D, Dohoo IR, Bate LA. Types of farm management as risk factors for swine respiratory disease. Prev Vet Med 1994, 20, 147-157. https://doi.org/10.1016/0167-5877(94)90113-9
  13. Hurnik D, Hanna PE, Dohoo IR. Evaluation of rapid gross visual appraisal of swine lungs at slaughter as a diagnostic screen for enzootic pneumonia. Can J Vet Res 1993, 57, 37-41.
  14. Hwang WM, Han JH. Prevalence of endemic diseases and effect on control of respiratory diseases in pig farms through slaughter check and management changes. Korean J Vet Public Health 2006, 30, 27-56.
  15. Kim NH, Hwang WM, Lee JG, Lee SM, Yang DS, Lee CH, Kim SJ, Han JH. Pathological observation of porcine respiratory disease in slaughter pigs. Korean J Vet Serv 2011, 34, 389-395. https://doi.org/10.7853/kjvs.2011.34.4.389
  16. Lee CH, Hwang WM, Lee JG, Lee SM, Kim SJ, Kim NH, Yang DS, Han JH. Study on gross finding of lung lesions and causative pathogens of porcine respiratory disease complex from slaughtered pigs in Incheon. Korean J Vet Serv 2011, 34, 313-320. https://doi.org/10.7853/kjvs.2011.34.4.313
  17. Madec F, Kobisch M. [Injury assessment of the lungs of pork butchers at the slaughterhouse]. J Rech Porcine 1982, 14, 405-412. French.
  18. Meyns T, Van Steelant J, Rolly E, Dewulf J, Haesebrouck F, Maes D. A cross-sectional study of risk factors associated with pulmonary lesions in pigs at slaughter. Vet J 2011, 187, 388-392. https://doi.org/10.1016/j.tvjl.2009.12.027
  19. Mousing J, Jensen PT, Halgaard C, Bager F, Feld N, Nielsen B, Nielsen JP, Bech-Nielsen S. Nation-wide Salmonella enterica surveillance and control in Danish slaughter swine herds. Prev Vet Med 1997, 29, 247-261. https://doi.org/10.1016/S0167-5877(96)01082-3
  20. Neumann EJ, Kliebenstein JB, Johnson CD, Mabry JW, Bush EJ, Seitzinger AH, Green AL, Zimmerman JJ. Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J Am Vet Med Assoc 2005, 227, 385-392. https://doi.org/10.2460/javma.2005.227.385
  21. Pedregosa F, Varoquaux, G, Gramfort A, Michel V, Thirion B, Grisel O, Blondel M, Prettenhofer P, Weiss R, Dubourg V, Vanderplas J, Passos A, Cournapeau D, Brucher M, Perrot M, Duchesnay E. Scikit-learn: machine learning in Python. J Mach Learn Res 2011, 12, 2825-2830.
  22. Redondo E, Masot AJ, Fernandez A, Gazquez A. Histopathological and immunohistochemical findings in the lungs of pigs infected experimentally with Mycoplasma hyopneumoniae. J Comp Pathol 2009, 140, 260-270. https://doi.org/10.1016/j.jcpa.2008.12.008
  23. Robertson J, Wilson D, Smith W. Atrophic rhinitis: the influence of the aerial environment. Anim Sci 1990, 50, 173-182.
  24. Rueda D, Bulnes C, Durand R, Bustamante P. Morphological evaluation of porcine pneumonias in slaughterhouses by using a score method. Rev Salud Anim 2002, 24, 208-212.
  25. Sibila M, Pieters M, Molitor T, Maes D, Haesebrouck F, Segales J. Current perspectives on the diagnosis and epidemiology of Mycoplasma hyopneumoniae infection. Vet J 2009, 181, 221-231. https://doi.org/10.1016/j.tvjl.2008.02.020
  26. Stark KDC. Epidemiological investigation of the influence of environmental risk factors on respiratory diseases in swine-a literature review. Vet J 2000, 159, 37-56. https://doi.org/10.1053/tvjl.1999.0421
  27. Stark KDC, Pfeiffer DU, Morris RS. Risk factors for respiratory diseases in New Zealand pig herds. N Z Vet J 1998, 46, 3-10. https://doi.org/10.1080/00480169.1998.36043
  28. Thacker EL. Diagnosis of Mycoplasma hyopneumoniae. Anim Health Res Rev 2004, 5, 317-320. https://doi.org/10.1079/AHR200491
  29. Thacker EL, Halbur PG, Ross RF, Thanawongnuwech R, Thacker BJ. Mycoplasma hyopneumoniae potentiation of porcine reproductive and respiratory syndrome virus-induced pneumonia. J Clin Microbiol 1999, 37, 620-627.
  30. VanAlstine WG. Respiratory system. In: Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW (eds.). Disease of Swine. 10th ed. pp. 353-355, Wiley Blackwell, Chichester, 2012.
  31. Vicca J, Stakenborg T, Maes D, Butaye P, Peeters J, de Kruif A, Haesebrouck F. Evaluation of virulence of Mycoplasma hyopneumoniae field isolates. Vet Microbiol 2003, 97, 177-190. https://doi.org/10.1016/j.vetmic.2003.08.008
  32. Wilson MR, Takov R, Friendship RM, Martin SW, McMillan I, Hacker RR, Swaminathan S. Prevalence of respiratory diseases and their association with growth rate and space in randomly selected swine herds. Can J Vet Res 1986, 50, 209-216.