DOI QR코드

DOI QR Code

Antimicrobial Activity of High Density Polyethylene Fabric Containing Scutellaria Baicalensis Extract-Loaded Zeolite Microparticles

황금추출물 담지 제올라이트 마이크로입자를 함유한 고밀도 폴리에틸렌 원단의 항균 특성

  • Lee, Sook-Young (Regional Innovation Center for Dental Science and Engineering,Chosun University) ;
  • Jo, Mi-Rae (Regional Innovation Center for Dental Science and Engineering,Chosun University) ;
  • Kim, Hyun-Jin (Institute for Biomaterials Research and Development, Kyungpook National University) ;
  • Kwon, Tae-Yub (Department Dental Biomaterials, Kyungpook National University) ;
  • Han, Hyunjung (Department of Clothing and Textile,University of Ulsan) ;
  • Yoon, Young Il (Korea Textile Development Institute) ;
  • Son, Jun Sik (Korea Textile Development Institute)
  • 이숙영 (조선대학교 치과용정밀장비 및 부품지역혁신센터) ;
  • 조미래 (조선대학교 치과용정밀장비 및 부품지역혁신센터) ;
  • 김현진 (경북대학교 생체재료연구소) ;
  • 권태엽 (경북대학교 치과재료학교실) ;
  • 한현정 (울산대학교 의류학과) ;
  • 윤영일 (한국섬유개발연구원) ;
  • 손준식 (한국섬유개발연구원)
  • Received : 2017.12.05
  • Accepted : 2017.12.19
  • Published : 2017.12.27

Abstract

Scutellaria Baicalensis(SB) is widely used in traditional and modern oriental medicine. It possesses several biology activities such as anti-oxidative, anti-inflammatory, antimicrobial and antiviral activities. In this study, a functional high density polyethylene (HDPE) fabric with antimicrobial properties was developed using zeolite microparticles as a SB extract delivery carrier. Zeolites loaded with SB extract were prepared by immersing in an SB extract aqueous solution. The average size of the SB extract-loaded zeolites was about 0.1 to $2.0{\mu}m$, and the morphology of the zeolites was not altered after SB extract binding. The resulting SB extract-loaded zeolites were then immobilized homogeneously onto the HDPE fabric using acrylic binder. The encapsulation efficiency of SB extract to the zeolite was more than 45%. The in vitro release test of SB extract-loaded zeolites containing HDPE fabrics showed release of 35% of the total SB extract by day 1 in a 24hours immersion study. Moreover, the SB extract-loaded zeolites containing HDPE fabrics showed effective antimicrobial activity against Streptococcus mutans, Staphylococcus aureus, and Klebsiella pneumoniae, indicating that this innovative delivery platform potently imparted antimicrobial activity to the HDPE fabric. In conclusion, the current study suggests that the HDPE fabric containing the SB extract-loaded zeolites microparticle carrier system has potential as an effective antimicrobial textile such as safety gloves, protective gloves etc.

Keywords

References

  1. M. K. Singh, V. K. Varun, and B. K. Behera, Cosmeto-textile: State of Art, Fibers and Textiles in Eastern Europe, 19(4), 27(2011).
  2. T. Kim, N. Cho, H. Ma, C. W. Yang, and Y. H. Rho, A Study on the Effect of Gallotannin Treatment of Ceramid-containing Fibers on Atopic Skin Diseases, Textile Coloration and Finishing, 25(4), 271(2013). https://doi.org/10.5764/TCF.2013.25.4.271
  3. K. S. Kim, S. S. Park, and J. H. Cha, Super Fiber, Ultralight and Ultra-high Strength Polyethylene Fiber, Fiber Technology and Industry, 15(1), 16(2011).
  4. J. Y. Paek, Y. H. Kim, H. J. Kwon, E. N. Kim, W. J. Kim, and M. D. Han, Effects of Antibacteria and Adhesive Inhibition of Scutellaria baicalensis Extract on Streptococcus mutans, J. of Dental Hygiene Science, 8(4), 367(2008).
  5. J. S. Rhee, E. R. Woo, N. H. Kim, E. J. Lee, D. K. An, J. H. Lee, S. K. Park, and H. K. Park, A Study on Qualitative and Quantitative Analysis of Major Ingredients in Scutellariae radix, Analytical Science and Technology, 10(2), 91(1997).
  6. J. H. Bae, M. J. Lee, and S. M. Lee, Antimicrobial Effect of Cutellaria Baicalensis George Extracts on Food-Borne Pathogens, Microbiology and Biotechnology Letters, 33(1), 35(2005).
  7. K. C. Leung, C. J. Senevirtne, X. Li, P. C. Leung, C. B. S. Lau, C. H. Wong, K. Y. Pang, C. W. Wong, E. Wat, and L. Jin, Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms, Nanomaterials, 6, 61(2016). https://doi.org/10.3390/nano6040061
  8. C. Duan, S. Matsumura, N. Kariya, M. Nishimura, and T. Shimono, In Vitro Antibacterials Activities of Scutellaria Baicalensis Georgi against Cariogenic Bacterials, J. of Pediatric Dentistry, 17, 58(2007).
  9. C. K. Lee and J. J. Seo, Antimicrobial Activity of Whangkumtang Extract and Scutellariae Radix Extract on the Food-Borne Pathogens, J. of the Korean Society of Food Science and Nutrition, 34(10), 1606(2005). https://doi.org/10.3746/jkfn.2005.34.10.1606
  10. O. K. Choi, Y. S. Kim, G. S. Cho, and C. K. Sung, Screening for Antimicrobial Activity from Korean Plants, J. of the Korean Society of Food Science and Nutrition, 25(4), 300(2002).
  11. H. S. Shin, M. J. Bae, D. W. Choi, and D. H. Shon, Skullcap(Scutellaria baicalensis) Extract and Its Active Compoun, Wogonin, Inhibit Ovalbumin-Induced Th2-Mediated Response, Molecules, 19(2), 2536(2014). https://doi.org/10.3390/molecules19022536
  12. J. Munoz-Pallares, A. Corma, J. Primo, and E. Primo-Yufera, Zeolites as Pheromone Dispensers, J. of Agricultural and Food Chemistry, 49, 4801(2001). https://doi.org/10.1021/jf010223o
  13. E. Perez, L. Martin, C. Rubio, J. S. Urieta, E. Piera, M. A. Caballero, C. Tellez, and J. Coronas, Encapsulation of ${\alpha}$-Tocopheryl Acetate into Zeolite Y for Textile Application, Industrial and Engineering Chemistry Research, 49, 8495(2010). https://doi.org/10.1021/ie100483v
  14. K. Kawahara, K. Tsuruda, M. Morishita, and M. Uchida, Antibacterial Effect of Silver-Zeolite on Oral Bacterial under Anaerobic Conditions, Dental Materials, 16(6), 452(2000). https://doi.org/10.1016/S0109-5641(00)00050-6
  15. J. Xing, X. Chen, Y. Sun, Y. Luan, and D. Zhong, Interaction of Baicalein with Antibioticsin the Gastrointestinal Tract, J. of Pharmacy and Pharmacology, 57(6), 743(2005). https://doi.org/10.1211/0022357056244
  16. Z. Blach-Olszewska and E. Lamer-Zarawska, Come Back to Root -Therapeutic Activities of Scutellaria baicalensis Root in Aspect of Innate Immunity Regulation-Part 1, Advances in Clinical and Experimental Medicine, 17, 337(2008).
  17. H. J. Kim, J. S. Son, K. H. Kim, and T. Y. Kwon, Antimicrobial Activity of Glass Ionomer Cement Incorporated with Chlorhexidine-Loaded Zeolite Nanoparticles, J. of Nanoscience and Nanotechnology, 16, 1450(2016). https://doi.org/10.1166/jnn.2016.11915
  18. A. M. Grancaric, A. Tarbuk, and I. Kovacek, Nanoparticles of Activated Natural Zeolite on Textiles for Protection and Therapy, Chemical Industry and Chemical Engineering Quarterly, 15(4), 203(2009). https://doi.org/10.2298/CICEQ0904203G