Archives of Craniofacial Surgery (대한두개안면성형외과학회지)

Korean Cleft Palate-Craniofacial Association (대한두개안면성형외과학회)
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Treatment of Tongue Lymphangioma with Intralesional Combination Injection of Steroid, Bleomycin and Bevacizumab

  • Hwang, Jungil (Department of Plastic Surgery, Kyung Hee University College of Medicine) ;
  • Lee, Yung Ki (Department of Plastic Surgery, Graduate School, Kyung Hee University) ;
  • Burm, Jin Sik (Department of Plastic Surgery, Kyung Hee University College of Medicine)
  • Received : 2016.09.02
  • Accepted : 2017.01.02
  • Published : 2017.03.20
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Abstract

Lymphangioma is a congenital malformed lymphatic tumor that rarely involves the tongue. In our clinic, a 10-year-old female presented with lymphangioma circumscriptum involving the right two-thirds of the tongue. We administered an intralesional combination injection of triamcinolone, bleomycin, and bevacizumab as a treatment. Almost complete remission after combination therapy was achieved without complications such as edema, swallowing difficulties or recurrence. Bevacizumab, an inhibitor of vascular endothelial growth factor, was effective for the treatment of lymphangioma of the tongue in this case. No recurrence was noted at the 1-year follow up.

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References

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