Sleep Medicine and Psychophysiology (수면정신생리)

KOREAN ACADEMY OF SLEEP MEDICINE (대한수면의학회)
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Obstructive Sleep Apnea in Interstitial Lung Disease

폐쇄성 수면 무호흡증과 간질성 폐질환

  • Kim, Shin Bum (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Lee, Sang Haak (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kang, Hyeon Hui (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
  • 김신범 (가톨릭대학교 의과대학 내과학교실) ;
  • 이상학 (가톨릭대학교 의과대학 내과학교실) ;
  • 강현희 (가톨릭대학교 의과대학 내과학교실)
  • Received : 2017.05.30
  • Accepted : 2017.06.19
  • Published : 2017.06.30
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Abstract

Obstructive sleep apnea is a common disorder in which respiratory flow decreases or disappears despite respiratory effort due to occlusion of the upper respiratory tract during sleep. Oxidative stress and systemic inflammatory reaction induced by the obstruction cause complications such as hypertension, coronary artery disease, and diabetes and increase cancer incidence. Furthermore, in patients with interstitial lung disease, obstructive sleep apnea has a very high prevalence and is thought to have a close pathophysiological and clinical correlation. In other words, obstructive sleep apnea could be the cause or a complication of interstitial lung disease ; when these two afflictions coexist, the prognosis of the patient is worse. In patients with interstitial lung disease with obstructive sleep apnea, CPAP treatment significantly improved sleep and quality of life, as well as improved morbidity and mortality in a recent study. Therefore, early diagnosis and treatment of obstructive sleep apnea in patients with interstitial lung disease are very important, and additional studies designed to include patients with idiopathic pulmonary fibrosis as well as patients with advanced interstitial lung disease should be performed.

Keywords

References

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