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무릎 골관절염의 봉독 약침 치료에 대한 체계적 문헌 고찰

A Systematic Review of Bee Venom Acupuncture for Knee Osteoarthritis

  • 구지향 (대전대학교 한의과대학 한방재활의학과) ;
  • 김은석 (대전대학교 한의과대학 침구의학과) ;
  • 박양춘 (대전대학교 한의과대학 한방내과) ;
  • 정인철 (대전대학교 한의과대학 한방신경정신과) ;
  • 이은정 (대전대학교 한의과대학 한방재활의학과)
  • Gu, Ji-Hyang (Department of Korean Rehabilitation Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Kim, Eunseok (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Park, Yang-Chun (Department of Internal Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Jung, In Chul (Department of Neuropsychiatry, College of Korean Medicine, Dae-Jeon University) ;
  • Lee, Eun-Jung (Department of Korean Rehabilitation Medicine, College of Korean Medicine, Dae-Jeon University)
  • 투고 : 2017.06.20
  • 심사 : 2017.07.15
  • 발행 : 2017.07.31

초록

Objectives The aim of this research is to assess the effects of bee venom acupuncture for knee osteoarthritis. Methods For a systematic review, we constructed a key question as the effect of bee venom acupuncture for knee osteoarthritis and selected RCTs and nRCTs. We searched the following 15 databases without a language restriction: Pubmed, EMBASE, Cochrane CENTRAL (CENTRAL), CINAHL, AMED, seven Korean medical databases (KoreaMed, Kmbase, KISS, NDSL, KISTI, Koreantk, OASIS) and three Chinese databases including CNKI, Wanfang and VIP database. Results A total of 300 potentially relevant studies were identified; only 13 studies were selected for systematic review. Almost studies showed that bee venom acupuncture has significant effect on knee osteoarthritis. 5 studies comparing bee venom acupuncture with acupuncture were included in the meta-analysis. The effect size of standardized mean difference (SMD) was analyzed as 'small effect' with 0.47 (95% CI: 0.10~0.83, Z=2.49, p=0.01). Conclusions The research showed that bee venom acupuncture can significantly reduce pain, stiffness and improve the quality of life of patients with knee osteoarthritis. However, most of the studies included in the analysis were evaluated as methodologically high risk of bias. This suggests that there is limitation applying this study. In the future, more Randomized Controlled trial should be actively conducted.

키워드

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